{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:05:37Z","timestamp":1792019137862,"version":"4.4.0"},"reference-count":74,"publisher":"American Spinal Injury Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Spinal cord stimulation (SCS) clinical trials are evaluating its efficacy and safety for motor, sensory, and autonomic recovery following spinal cord injury (SCI). The perspectives of people living with SCI are not well known and can inform the planning, delivery, and translation of SCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To obtain input from people living with SCI on the top priorities for recovery, expected meaningful benefits, risk tolerance, clinical trial design, and overall interest in SCS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were collected anonymously from an online survey between February and May 2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 223 respondents living with SCI completed the survey. The majority of respondents identified their gender as male (64%), were 10+ years post SCI (63%), and had a mean age of 50.8 years. Most individuals had a traumatic SCI (81%), and 45% classified themselves as having tetraplegia. Priorities for improved outcome for those with complete or incomplete tetraplegia included fine motor skills and upper body function, whereas priorities for complete or incomplete paraplegia included standing and walking, and bowel function. The meaningful benefits that are important to achieve are bowel and bladder care, less reliance on caregivers, and maintaining physical health. Perceived potential risks include further loss of function, neuropathic pain, and complications. Barriers to participation in clinical trials include inability to relocate, out-of-pocket expenses, and awareness of therapy. Respondents were more interested in transcutaneous SCS than epidural SCS (80% and 61%, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SCS clinical trial design, participant recruitment, and translation of the technology can be improved by better reflecting the priorities and preferences of those living with SCI identified from this study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.46292\/sci22-00057","type":"journal-article","created":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T22:37:33Z","timestamp":1684967853000},"page":"1-11","source":"Crossref","is-referenced-by-count":16,"title":["Spinal Cord Injury Community Personal Opinions and Perspectives on Spinal Cord Stimulation"],"prefix":"10.46292","volume":"29","author":[{"given":"Nancy P.","family":"Thorogood","sequence":"first","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeina","family":"Waheed","sequence":"additional","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Chernesky","sequence":"additional","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Burkhart","sequence":"additional","affiliation":[{"name":"North American Spinal Cord Injury Consortium, Niagara Falls, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Smith","sequence":"additional","affiliation":[{"name":"North American Spinal Cord Injury Consortium, Niagara Falls, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Sweeney","sequence":"additional","affiliation":[{"name":"North American Spinal Cord Injury Consortium, Niagara Falls, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Wudlick","sequence":"additional","affiliation":[{"name":"North American Spinal Cord Injury Consortium, Niagara Falls, New York"},{"name":"Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Douglas","sequence":"additional","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Wang","sequence":"additional","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa K.","family":"Noonan","sequence":"additional","affiliation":[{"name":"Praxis Spinal Cord Institute, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25425","reference":[{"key":"i1945-5763-29-2-1-b1","unstructured":"About neuromodulation. 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A review of spinal cord injury consumer priorities and neuroprosthesis from the 2008 neural interfaces conference","volume":"13","year":"2010","unstructured":"French\n              JS,\n            \n            \n              Anderson-Erisman\n              KD,\n            \n            \n              Sutter\n              M.\n            \n          \n          What do spinal cord injury consumers want? 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Neurol","first-page":"536","article-title":"Historical development and contemporary use of neuromodulation in human spinal cord injury","volume":"35","year":"2022","unstructured":"Harkema\n              S,\n            \n            \n              Angeli\n              C,\n            \n            \n              Gerasimenko\n              Y.\n            \n          \n          Historical development and contemporary use of neuromodulation in human spinal cord injury.\n\t\t\t\t\tCurr Opin Neurol.\n\t\t\t\t\t2022;\n\t\t\t\t\t35(\n\t\t\t\t\t4):\n\t\t\t\t\t536\u2013\n\t\t\t\t\t543."},{"issue":"9781","key":"i1945-5763-29-2-1-b6","series-title":"Lancet (Lond)","first-page":"1938","article-title":"Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: A case study","volume":"377","year":"2011","unstructured":"Harkema\n              S,\n            \n            \n              Gerasimenko\n      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Neurotrauma","first-page":"1787","article-title":"Effects of stand and step training with epidural stimulation on motor function for standing in chronic complete paraplegics","volume":"34","year":"2017","unstructured":"Rejc\n              E,\n            \n            \n              Angeli\n              CA,\n            \n            \n              Bryant\n              N,\n            \n            \n              Harkema\n              SJ.\n            \n          \n          Effects of stand and step training with epidural stimulation on motor function for standing in chronic complete paraplegics.\n\t\t\t\t\tJ Neurotrauma.\n\t\t\t\t\t2017;\n\t\t\t\t\t34(\n\t\t\t\t\t9):\n\t\t\t\t\t1787\u2013\n\t\t\t\t\t1802."},{"issue":"7","key":"i1945-5763-29-2-1-b10","series-title":"PLoS One","first-page":"1","article-title":"Effects of lumbosacral spinal cord epidural stimulation for standing after chronic complete paralysis in humans","volume":"10","year":"2015","unstructured":"Rejc\n          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Neurotrauma","first-page":"2325","article-title":"Epidural spinal cord stimulation facilitates immediate restoration of dormant motor and autonomic supraspinal pathways after chronic neurologically complete spinal cord injury","volume":"36","year":"2019","unstructured":"Darrow\n              D,\n            \n            \n              Balser\n              D,\n            \n            \n              Netoff\n              TI,\n            \n          \n          .\n\t\t\t\t\tEpidural spinal cord stimulation facilitates immediate restoration of dormant motor and autonomic supraspinal pathways after chronic neurologically complete spinal cord injury.\n\t\t\t\t\tJ Neurotrauma.\n\t\t\t\t\t2019;\n\t\t\t\t\t36(\n\t\t\t\t\t15):\n\t\t\t\t\t2325\u2013\n\t\t\t\t\t2336."},{"issue":"10","key":"i1945-5763-29-2-1-b14","series-title":"Artif Organs","first-page":"E176","article-title":"Augmentation of voluntary locomotor activity by transcutaneous spinal cord stimulation in motor-incomplete spinal 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Physiol","first-page":"492","article-title":"Spinal and sensory neuromodulation of spinal neuronal networks in humans","volume":"43","year":"2017","unstructured":"Gerasimenko\n              YP,\n            \n            \n              McKinney\n              Z,\n            \n            \n              Sayenko\n              DG,\n            \n          \n          .\n\t\t\t\t\tSpinal and sensory neuromodulation of spinal neuronal networks in humans.\n\t\t\t\t\tHum Physiol.\n\t\t\t\t\t2017;\n\t\t\t\t\t43(\n\t\t\t\t\t5):\n\t\t\t\t\t492\u2013\n\t\t\t\t\t500."},{"key":"i1945-5763-29-2-1-b18","series-title":"Front Neurosci","first-page":"1","article-title":"Weight bearing over-ground stepping in an exoskeleton with non-invasive spinal cord neuromodulation after motor complete paraplegia","volume":"11","year":"2017","unstructured":"Gad\n              P,\n            \n            \n              Gerasimenko\n              Y,\n            \n            \n              Zdunowski\n          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Neurotrauma","first-page":"446","article-title":"An autonomic neuroprosthesis: Noninvasive electrical spinal cord stimulation restores autonomic cardiovascular function in individuals with spinal cord injury","volume":"35","year":"2018","unstructured":"Phillips\n              AA,\n            \n            \n              Squair\n              JW,\n            \n            \n              Sayenko\n              DG,\n            \n            \n              Edgerton\n              VR,\n            \n            \n              Gerasimenko\n              Y,\n            \n            \n              Krassioukov\n              AV.\n            \n          \n          An autonomic neuroprosthesis: Noninvasive electrical spinal cord stimulation restores autonomic cardiovascular function in individuals with spinal cord injury.\n\t\t\t\t\tJ 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function for individuals living with spinal cord injuries: A scoping review","volume":"103","year":"2022","unstructured":"Laskin\n              JJ,\n            \n            \n              Waheed\n              Z,\n            \n            \n              Thorogood\n              NP,\n            \n            \n              Nightingale\n              TE,\n            \n            \n              Noonan\n              VK.\n            \n          \n          Spinal cord stimulation research in the restoration of motor, sensory, and autonomic function for individuals living with spinal cord injuries: A scoping review.\n\t\t\t\t\tArch Phys Med Rehabil.\n\t\t\t\t\t2022;\n\t\t\t\t\t103(\n\t\t\t\t\t7):\n\t\t\t\t\t1387\u2013\n\t\t\t\t\t1397."},{"issue":"Suppl 1","key":"i1945-5763-29-2-1-b24","series-title":"Biomed Tech (Berl)","article-title":"Mechanisms of rhythm generation of the human lumbar spinal cord in response to tonic stimulation without and with step-related sensory feedback","volume":"58","year":"2013","unstructured":"Minassian\n              K,\n            \n            \n              Hofstoetter\n              US,\n            \n            \n              Danner\n              SM,\n            \n          \n          .\n\t\t\t\t\tMechanisms of rhythm generation of the human lumbar spinal cord in response to tonic stimulation without and with step-related sensory feedback.\n\t\t\t\t\tBiomed Tech (Berl).\n\t\t\t\t\t2013;\n\t\t\t\t\t58(\n\t\t\t\t\tSuppl 1)."},{"issue":"1","key":"i1945-5763-29-2-1-b25","series-title":"Sci Rep","first-page":"8688","article-title":"Lumbosacral spinal cord epidural stimulation improves voiding function after human spinal cord injury","volume":"8","year":"2018","unstructured":"Herrity\n              AN,\n            \n            \n              Williams\n              CS,\n            \n            \n              Angeli\n              CA,\n            \n            \n              Harkema\n              SJ,\n      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Policy","first-page":"187","article-title":"A critical second look at integrated knowledge translation","volume":"109","year":"2013","unstructured":"Kothari\n              A,\n            \n            \n              Wathen\n              CN.\n            \n          \n          A critical second look at integrated knowledge translation.\n\t\t\t\t\tHealth Policy.\n\t\t\t\t\t2013;\n\t\t\t\t\t109(\n\t\t\t\t\t2):\n\t\t\t\t\t187\u2013\n\t\t\t\t\t191."},{"issue":"1","key":"i1945-5763-29-2-1-b28","series-title":"Implement Sci","first-page":"1","article-title":"Moving knowledge into action for more effective practice, programmes and policy: Protocol for a research programme on integrated knowledge translation","volume":"13","year":"2018","unstructured":"Graham\n              ID,\n            \n            \n              Kothari\n              A,\n            \n            \n              McCutcheon\n              C,\n            \n          \n          .\n\t\t\t\t\tMoving knowledge into action for more effective practice, programmes and policy: Protocol for a research programme on integrated knowledge translation.\n\t\t\t\t\tImplement Sci.\n\t\t\t\t\t2018;\n\t\t\t\t\t13(\n\t\t\t\t\t1):\n\t\t\t\t\t1\u2013\n\t\t\t\t\t15."},{"issue":"10","key":"i1945-5763-29-2-1-b29","series-title":"J Neurotrauma","first-page":"1371","article-title":"Targeting recovery: Priorities of the spinal cord-injured population","volume":"21","year":"2004","unstructured":"Anderson\n              KD.\n            \n          \n          Targeting recovery: Priorities of the spinal cord-injured population.\n\t\t\t\t\tJ Neurotrauma.\n\t\t\t\t\t2004;\n\t\t\t\t\t21(\n\t\t\t\t\t10):\n\t\t\t\t\t1371\u2013\n\t\t\t\t\t1383."},{"issue":"6","key":"i1945-5763-29-2-1-b30","series-title":"J Rehabil Res Dev","first-page":"655","article-title":"Neuroprosthesis consumers\u2019 forum: Consumer priorities for research directions","volume":"38","year":"2001","unstructured":"Kilgore\n              KL,\n            \n  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A review of spinal cord injury consumer priorities and neuroprosthesis from the 2008 neural interfaces conference","volume":"13","year":"2010","unstructured":"French\n              JS,\n            \n            \n              Anderson-Erisman\n              KD,\n            \n            \n              Sutter\n              M.\n            \n          \n          What do spinal cord injury consumers want? A review of spinal cord injury consumer priorities and neuroprosthesis from the 2008 neural interfaces conference.\n\t\t\t\t\tNeuromodulation.\n\t\t\t\t\t2010;\n\t\t\t\t\t13(\n\t\t\t\t\t3):\n\t\t\t\t\t229\u2013\n\t\t\t\t\t231."},{"key":"i1945-5763-29-2-1-b32","series-title":"J Neurotrauma","article-title":"The health and life priorities of individuals with spinal cord injury: A systematic review","unstructured":"Simpson\n              LA,\n            \n            \n              Eng\n              JJ,\n            \n            \n              Hsieh\n              JTC,\n            \n            \n              Wolfe\n              DL.\n            \n          \n          The health and life priorities of individuals with spinal cord injury: A systematic review.\n\t\t\t\t\tJ Neurotrauma."},{"issue":"21","key":"i1945-5763-29-2-1-b33","series-title":"J Neurotrauma","first-page":"1958","article-title":"Functional priorities in persons with spinal cord injury: Using discrete choice experiments to determine preferences","volume":"33","year":"2016","unstructured":"Lo\n              C,\n            \n            \n              Tran\n              Y,\n            \n            \n              Anderson\n              K,\n            \n            \n              Craig\n              A,\n            \n            \n              Middleton\n              J.\n            \n          \n          Functional priorities in persons with spinal cord injury: Using discrete choice experiments to determine preferences.\n\t\t\t\t\tJ Neurotrauma.\n\t\t\t\t\t2016;\n\t\t\t\t\t33(\n\t\t\t\t\t21):\n\t\t\t\t\t1958\u2013\n\t\t\t\t\t1968."},{"issue":"9","key":"i1945-5763-29-2-1-b34","series-title":"Spinal Cord","first-page":"998","article-title":"Recovery target priorities of people with spinal cord injuries in Korea compared with other countries: A survey","volume":"58","year":"2020","unstructured":"Huh\n              S,\n            \n            \n              Ko\n              HY.\n 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of epidural stimulation for functional improvement after spinal cord injury","volume":"43","year":"2020","unstructured":"Solinsky\n              R,\n            \n            \n              Specker-Sullivan\n              L,\n            \n            \n              Wexler\n              A.\n            \n          \n          Current barriers and ethical considerations for clinical implementation of epidural stimulation for functional improvement after spinal cord injury.\n\t\t\t\t\tJ Spinal Cord Med.\n\t\t\t\t\t2020;\n\t\t\t\t\t43(\n\t\t\t\t\t5):\n\t\t\t\t\t653\u2013\n\t\t\t\t\t656."}],"container-title":["Topics in Spinal Cord Injury 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