{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:57:32Z","timestamp":1790863052443,"version":"4.1.0"},"reference-count":158,"publisher":"American Spinal Injury Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"\n Background:<\/jats:title>\n Spinal cord injuries (SCI) often result in cardiovascular issues, increasing the risk of stroke and cognitive deficits.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n This study assessed cerebrovascular reactivity (CVR) using functional magnetic resonance imaging (fMRI) during a hypercapnic challenge in SCI participants compared to noninjured controls.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n Fourteen participants were analyzed (\n n<\/jats:italic>\n = 8 with SCI [unless otherwise noted], median age = 44 years;\n n<\/jats:italic>\n = 6 controls, median age = 33 years). CVR was calculated through fMRI signal changes.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The results showed a longer CVR component (tau) in the grey matter of SCI participants (\n n<\/jats:italic>\n = 7) compared to controls (median difference = 3.0 s;\n p<\/jats:italic>\n < .05). Time since injury (TSI) correlated negatively with steady-state CVR in the grey matter and brainstem of SCI participants (\n R<\/jats:italic>\n S<\/jats:sub>\n = \u22120.81,\n p<\/jats:italic>\n = .014;\n R<\/jats:italic>\n S<\/jats:sub>\n = \u22120.84,\n p<\/jats:italic>\n = .009, respectively). Lower steady-state CVR in the brainstem of the SCI group (\n n<\/jats:italic>\n = 7) correlated with lower diastolic blood pressure (\n R<\/jats:italic>\n S<\/jats:sub>\n = 0.76,\n p<\/jats:italic>\n = .046). Higher frequency of hypotensive episodes (\n n<\/jats:italic>\n = 7) was linked to lower CVR outcomes in the grey matter (\n R<\/jats:italic>\n S<\/jats:sub>\n = \u22120.86,\n p<\/jats:italic>\n = .014) and brainstem (\n R<\/jats:italic>\n S<\/jats:sub>\n = \u22120.89,\n p<\/jats:italic>\n = .007).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Preliminary findings suggest a difference in the dynamic CVR component, tau, between the SCI and noninjured control groups, potentially explaining the higher cerebrovascular health burden in SCI individuals. Exploratory associations indicate that longer TSI, lower diastolic blood pressure, and more hypotensive episodes may lead to poorer CVR outcomes. However, further research is necessary to establish causality and support these observations.<\/jats:p>\n <\/jats:sec>","DOI":"10.46292\/sci23-00068","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:53:34Z","timestamp":1716512014000},"page":"78-95","source":"Crossref","is-referenced-by-count":6,"title":["Cerebrovascular Reactivity Following Spinal Cord Injury"],"prefix":"10.46292","volume":"30","author":[{"given":"Alexander Mark","family":"Weber","sequence":"first","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada"},{"name":"BC Children's Hospital Research Institute, Vancouver, BC, Canada"},{"name":"School of Biomedical Engineering, University of British Columbia, British Columbia, Canada"},{"name":"Department of Neuroscience, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom E.","family":"Nightingale","sequence":"additional","affiliation":[{"name":"School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK"},{"name":"Centre for Trauma Sciences Research, University of Birmingham, Edgbaston, Birmingham, UK"},{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Jarrett","sequence":"additional","affiliation":[{"name":"MRI Research Centre, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda H. X.","family":"Lee","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia Lauren","family":"Campbell","sequence":"additional","affiliation":[{"name":"BC Children's Hospital Research Institute, Vancouver, BC, Canada"},{"name":"School of Biomedical Engineering, University of British Columbia, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Walter","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada"},{"name":"Department of Urology, University Hospital Basel, University of Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel J. E.","family":"Lucas","sequence":"additional","affiliation":[{"name":"School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK"},{"name":"Centre for Human Brain Health, University of Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"Phillips","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada"},{"name":"Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada"},{"name":"Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada"},{"name":"Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada"},{"name":"RestoreNetwork, Hotchkiss Brain Institute, Libin Cardiovascular Institute, McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Rauscher","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada"},{"name":"BC Children's Hospital Research Institute, Vancouver, BC, Canada"},{"name":"MRI Research Centre, University of British Columbia, Vancouver, Canada"},{"name":"Department of Astronomy and Physics, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei V.","family":"Krassioukov","sequence":"additional","affiliation":[{"name":"International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, Canada"},{"name":"G.F. Strong Rehabilitation Centre, Vancouver, BC, Canada"},{"name":"Division of Physical Medicine and Rehabilitation, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25425","reference":[{"issue":"8","key":"b1","series-title":"Neurology","first-page":"723","article-title":"Cardiovascular disease and spinal cord injury: Results from a national population health survey","volume":"81","author":"Cragg\n JJ","year":"2013","unstructured":"Cragg\n JJ\n , NoonanVK, KrassioukovA, BorisoffJ. Cardiovascular disease and spinal cord injury: Results from a national population health survey. Neurology. 2013;81(8):723-728."},{"issue":"14","key":"b2","series-title":"Neurology","first-page":"1051","article-title":"Increased risk of stroke after spinal cord injury: A nationwide 4-year follow-up cohort study","volume":"78","author":"Wu\n JC","year":"2012","unstructured":"Wu\n JC\n , ChenYC, LiuL, et al.\n Increased risk of stroke after spinal cord injury: A nationwide 4-year follow-up cohort study. Neurology. 2012;78(14):1051-1057."},{"issue":"13","key":"b3","series-title":"Neurology","first-page":"611","article-title":"Cognitive function after spinal cord injury: A systematic review","volume":"91","author":"Sachdeva\n R","year":"2018","unstructured":"Sachdeva\n R\n , GaoF, ChanCCH, KrassioukovAV. Cognitive function after spinal cord injury: A systematic review. Neurology. 2018;91(13):611-621."},{"issue":"10","key":"b4","series-title":"Int J Mol Sci","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20102464","article-title":"The blood pressure pendulum following spinal cord injury: Implications for vascular cognitive impairment","volume":"20","author":"Sachdeva\n R","year":"2019","unstructured":"Sachdeva\n R\n , NightingaleTE, KrassioukovAV. The blood pressure pendulum following spinal cord injury: Implications for vascular cognitive impairment. Int J Mol Sci. 2019;20(10). doi:10.3390\/ijms20102464"},{"key":"b5","series-title":"Auton Neurosci","first-page":"43","article-title":"Alterations in autonomic cerebrovascular control after spinal cord injury","volume":"209","author":"Kim\n DI","year":"2018","unstructured":"Kim\n DI\n , TanCO. Alterations in autonomic cerebrovascular control after spinal cord injury. Auton Neurosci. 2018;209:43-50."},{"issue":"24","key":"b6","series-title":"J Neurotrauma","first-page":"1927","article-title":"Contemporary cardiovascular concerns after spinal cord injury: Mechanisms, maladaptations, and management","volume":"32","author":"Phillips\n AA","year":"2015","unstructured":"Phillips\n AA\n , KrassioukovAV. Contemporary cardiovascular concerns after spinal cord injury: Mechanisms, maladaptations, and management. J Neurotrauma. 2015;32(24):1927-1942."},{"issue":"5","key":"b7","series-title":"Semin Neurol","first-page":"550","article-title":"Cardiovascular autonomic dysfunction in spinal cord injury: Epidemiology, diagnosis, and management","volume":"40","author":"Wecht\n JM","year":"2020","unstructured":"Wecht\n JM\n , HarelNY, GuestJ, et al.\n Cardiovascular autonomic dysfunction in spinal cord injury: Epidemiology, diagnosis, and management. Semin Neurol. 2020;40(5):550-559."},{"issue":"5","key":"b8","series-title":"J Physiol","first-page":"841","article-title":"Integrative regulation of human brain blood flow","volume":"592","author":"Willie\n CK","year":"2014","unstructured":"Willie\n CK\n , TzengYC, FisherJA, AinsliePN. Integrative regulation of human brain blood flow. J Physiol. 2014;592(5):841-859."},{"issue":"3","key":"b9","series-title":"Hypertension","first-page":"698","article-title":"Influence of changes in blood pressure on cerebral perfusion and oxygenation","volume":"55","author":"Lucas\n SJE","year":"2010","unstructured":"Lucas\n SJE\n , TzengYC, GalvinSD, ThomasKN, OgohS, AinsliePN. Influence of changes in blood pressure on cerebral perfusion and oxygenation. Hypertension. 2010;55(3):698-705."},{"issue":"4","key":"b10","series-title":"J Spinal Cord Med","first-page":"606","article-title":"PRES secondary to autonomic dysreflexia: A case series and review of the literature","volume":"44","author":"Hubbard\n ME","year":"2021","unstructured":"Hubbard\n ME\n , PhillipsAA, CharbonneauR, SquairJW, ParrAM, KrassioukovA. PRES secondary to autonomic dysreflexia: A case series and review of the literature. J Spinal Cord Med. 2021;44(4):606-612."},{"issue":"1","key":"b11","series-title":"J Spinal Cord Med","first-page":"2","article-title":"Life-threatening outcomes associated with autonomic dysreflexia: A clinical review","volume":"37","author":"Wan\n D","year":"2014","unstructured":"Wan\n D\n , KrassioukovAV. Life-threatening outcomes associated with autonomic dysreflexia: A clinical review. J Spinal Cord Med. 2014;37(1):2-10."},{"issue":"18","key":"b12","series-title":"J Neurotrauma","first-page":"1963","article-title":"Vascular-cognitive impairment following high-thoracic spinal cord injury is associated with structural and functional maladaptations in cerebrovasculature","volume":"37","author":"Sachdeva\n R","year":"2020","unstructured":"Sachdeva\n R\n , JiaM, WangS, et al.\n Vascular-cognitive impairment following high-thoracic spinal cord injury is associated with structural and functional maladaptations in cerebrovasculature. J Neurotrauma. 2020;37(18):1963-1970."},{"issue":"3","key":"b13","series-title":"J Neurotrauma","first-page":"573","article-title":"Transient hypertension after spinal cord injury leads to cerebrovascular endothelial dysfunction and fibrosis","volume":"35","author":"Phillips\n AA","year":"2018","unstructured":"Phillips\n AA\n , MatinN, JiaM, et al.\n Transient hypertension after spinal cord injury leads to cerebrovascular endothelial dysfunction and fibrosis. J Neurotrauma. 2018;35(3):573-581."},{"issue":"9735","key":"b14","series-title":"Lancet","first-page":"112","article-title":"Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study","volume":"376","author":"O'Donnell\n MJ","year":"2010","unstructured":"O'Donnell\n MJ\n , XavierD, LiuL, et al.\n Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. Lancet. 2010;376(9735):112-123."},{"key":"b15","series-title":"Nat Rev Dis Primers","first-page":"18003","article-title":"Vascular cognitive impairment","volume":"4","author":"van der Flier\n WM","year":"2018","unstructured":"van der Flier\n WM\n , SkoogI, SchneiderJA, et al.\n Vascular cognitive impairment. Nat Rev Dis Primers. 2018;4:18003."},{"issue":"Pt 3","key":"b16","series-title":"Brain","first-page":"457","article-title":"Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion","volume":"124","author":"Markus\n H","year":"2001","unstructured":"Markus\n H\n , CullinaneM. Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion. Brain. 2001;124(Pt 3):457-467."},{"key":"b17","series-title":"J Exp Neurosci","first-page":"1179069518785151","article-title":"Regional cerebrovascular reactivity and cognitive performance in healthy aging","volume":"12","author":"Catchlove\n SJ","year":"2018","unstructured":"Catchlove\n SJ\n , ParrishTB, ChenY, MacphersonH, HughesME, PipingasA. Regional cerebrovascular reactivity and cognitive performance in healthy aging. J Exp Neurosci. 2018;12:1179069518785151."},{"issue":"23","key":"b18","series-title":"J Physiol","first-page":"5809","article-title":"Measuring cerebrovascular reactivity: What stimulus to use?","volume":"591","author":"Fierstra\n J","year":"2013","unstructured":"Fierstra\n J\n , SobczykO, Battisti-CharbonneyA, et al.\n Measuring cerebrovascular reactivity: What stimulus to use?\n J Physiol. 2013;591(23):5809-5821."},{"key":"b19","series-title":"Front Physiol","first-page":"629651","article-title":"Cerebrovascular reactivity: Purpose, optimizing methods, and limitations to interpretation - A personal 20-year odyssey of (re) searching","volume":"12","author":"Fisher\n JA","year":"2021","unstructured":"Fisher\n JA\n , MikulisDJ. Cerebrovascular reactivity: Purpose, optimizing methods, and limitations to interpretation - A personal 20-year odyssey of (re) searching. Front Physiol. 2021;12:629651."},{"issue":"5","key":"b20","series-title":"J Cereb Blood Flow Metab","first-page":"794","article-title":"Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: Improved by alpha-1 agonist midodrine hydrochloride","volume":"34","author":"Phillips\n AA","year":"2014","unstructured":"Phillips\n AA\n , WarburtonDER, AinsliePN, KrassioukovAV. Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: Improved by alpha-1 agonist midodrine hydrochloride. J Cereb Blood Flow Metab. 2014;34(5):794-801."},{"issue":"7775","key":"b21","series-title":"Lancet","first-page":"457","article-title":"Absence of cerebral vasoconstriction with hyperventilation in tetraplegic man. Evidence for neurogenic control of cerebral circulation","volume":"2","author":"Eidelman\n BH","year":"1972","unstructured":"Eidelman\n BH\n , DebargeO, CorbettJL, FrankelH. Absence of cerebral vasoconstriction with hyperventilation in tetraplegic man. Evidence for neurogenic control of cerebral circulation. Lancet. 1972;2(7775):457-460."},{"issue":"1","key":"b22","series-title":"J Neurol Sci","first-page":"129","article-title":"The effect of hypocapnia and change of blood pressure on cerebral blood flow in men with cervical spinal cord transection","volume":"30","author":"Nanda\n RN","year":"1976","unstructured":"Nanda\n RN\n , WyperDJ, JohnsonRH, HarperAM. The effect of hypocapnia and change of blood pressure on cerebral blood flow in men with cervical spinal cord transection. J Neurol Sci. 1976;30(1):129-135."},{"issue":"4","key":"b23","series-title":"Am J Physiol Regul Integr Comp Physiol","first-page":"R1035","article-title":"Cerebrovascular reactivity and dynamic autoregulation in tetraplegia","volume":"298","author":"Wilson\n LC","year":"2010","unstructured":"Wilson\n LC\n , CotterJD, FanJL, LucasRAI, ThomasKN, AinsliePN. Cerebrovascular reactivity and dynamic autoregulation in tetraplegia. Am J Physiol Regul Integr Comp Physiol. 2010;298(4):R1035-R1042."},{"key":"b24","series-title":"Front Physiol","first-page":"656746","article-title":"Contrasting measures of cerebrovascular reactivity between MRI and Doppler: A cross-sectional study of younger and older healthy individuals","volume":"12","author":"Burley\n CV","year":"2021","unstructured":"Burley\n CV\n , FrancisST, ThomasKN, WhittakerAC, LucasSJE, MullingerKJ. Contrasting measures of cerebrovascular reactivity between MRI and Doppler: A cross-sectional study of younger and older healthy individuals. Front Physiol. 2021;12:656746."},{"key":"b25","series-title":"Front Physiol","first-page":"665049","article-title":"Measuring cerebrovascular reactivity: Sixteen avoidable pitfalls","volume":"12","author":"Sobczyk\n O","year":"2021","unstructured":"Sobczyk\n O\n , FierstraJ, VenkatraghavanL, et al.\n Measuring cerebrovascular reactivity: Sixteen avoidable pitfalls. Front Physiol. 2021;12:665049."},{"issue":"8","key":"b26","series-title":"Stroke","first-page":"2011","article-title":"Magnetic resonance imaging-based cerebrovascular reactivity and hemodynamic reserve","volume":"49","author":"Fisher\n JA","year":"2018","unstructured":"Fisher\n JA\n , VenkatraghavanL, MikulisDJ. Magnetic resonance imaging-based cerebrovascular reactivity and hemodynamic reserve. Stroke. 2018;49(8):2011-2018."},{"issue":"3","key":"b27","series-title":"Proc Natl Acad Sci USA","first-page":"1753","article-title":"Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice","volume":"17","author":"Wenzel\n J","year":"2020","unstructured":"Wenzel\n J\n , HansenCE, BettoniC, et al.\n Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice. Proc Natl Acad Sci USA. 2020;117(3):1753-1761."},{"issue":"6","key":"b28","series-title":"J Cereb Blood Flow Metab","first-page":"1004","article-title":"The CO2 stimulus for cerebrovascular reactivity: Fixing inspired concentrations vs. targeting end-tidal partial pressures","volume":"36","author":"Fisher\n JA","year":"2016","unstructured":"Fisher\n JA\n \n . The CO2 stimulus for cerebrovascular reactivity: Fixing inspired concentrations vs. targeting end-tidal partial pressures. J Cereb Blood Flow Metab. 2016;36(6):1004-1011."},{"issue":"9","key":"b29","series-title":"J Cereb Blood Flow Metab","first-page":"1042","article-title":"Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response","volume":"22","author":"Cohen\n ER","year":"2002","unstructured":"Cohen\n ER\n , UgurbilK, KimSG. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J Cereb Blood Flow Metab. 2002;22(9):1042-1053."},{"issue":"4","key":"b30","series-title":"Neuroimage","first-page":"1642","article-title":"Vascular dynamics and BOLD fMRI: CBF level effects and analysis considerations","volume":"32","author":"Vazquez\n AL","year":"2006","unstructured":"Vazquez\n AL\n , CohenER, GulaniV, et al.\n Vascular dynamics and BOLD fMRI: CBF level effects and analysis considerations. Neuroimage. 2006;32(4):1642-1655."},{"issue":"2","key":"b31","series-title":"Neuroimage","first-page":"579","article-title":"Impaired cerebral vasoreactivity to CO2 in Alzheimer's disease using BOLD fMRI","volume":"58","author":"Cantin\n S","year":"2011","unstructured":"Cantin\n S\n , VillienM, MoreaudO, et al.\n Impaired cerebral vasoreactivity to CO2 in Alzheimer's disease using BOLD fMRI. Neuroimage. 2011;58(2):579-587."},{"issue":"6","key":"b32","series-title":"J Spinal Cord Med","first-page":"535","article-title":"International Standards for Neurological Classification of Spinal Cord Injury (revised 2011)","volume":"34","author":"Kirshblum\n SC","year":"2011","unstructured":"Kirshblum\n SC\n , BurnsSP, Biering-SorensenF, et al.\n International Standards for Neurological Classification of Spinal Cord Injury (revised 2011). J Spinal Cord Med. 2011;34(6):535-546."},{"issue":"9","key":"b33","series-title":"Magn Reson Imaging","first-page":"995","article-title":"Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions","volume":"21","author":"Brevard\n ME","year":"2003","unstructured":"Brevard\n ME\n , DuongTQ, KingJA, FerrisCF. Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions. Magn Reson Imaging. 2003;21(9):995-1001."},{"issue":"2","key":"b34","series-title":"Neuroimage","first-page":"87","article-title":"Regional differences in the CBF and BOLD responses to hypercapnia: A combined PET and fMRI study","volume":"11","author":"Rostrup\n E","year":"2000","unstructured":"Rostrup\n E\n , LawI, BlinkenbergM, et al.\n Regional differences in the CBF and BOLD responses to hypercapnia: A combined PET and fMRI study. Neuroimage. 2000;11(2):87-97."},{"issue":"6","key":"b35","series-title":"J Cereb Blood Flow Metab","first-page":"1036","article-title":"Safety of hypercapnic challenge: Cardiovascular and neurologic considerations","volume":"11","author":"Gitelman\n DR","year":"1991","unstructured":"Gitelman\n DR\n , ProhovnikI, TatemichiTK. Safety of hypercapnic challenge: Cardiovascular and neurologic considerations. J Cereb Blood Flow Metab. 1991;11(6):1036-1040."},{"key":"b36","series-title":"Poldracklab\/fmriprep: 1.0.0-rc5","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.996169","author":"Esteban\n O","year":"2017","unstructured":"Esteban\n O\n , BlairR, MarkiewiczCJ, et al.\n Poldracklab\/fmriprep: 1.0.0-rc5. 2017. doi:10.5281\/zenodo.996169"},{"issue":"2","key":"b37","series-title":"Neuroimage","first-page":"782","article-title":"FSL","volume":"62","author":"Jenkinson\n M","year":"2012","unstructured":"Jenkinson\n M\n , BeckmannCF, BehrensTEJ, WoolrichMW, SmithSM. FSL. Neuroimage. 2012;62(2):782-790."},{"key":"b38","series-title":"OR Insight","doi-asserted-by":"publisher","first-page":"1","DOI":"10.54294\/uvnhin","article-title":"Advanced normalization tools (ANTS)","author":"Avants\n BB","year":"2008","unstructured":"Avants\n BB\n , TustisonN, SongG. Advanced normalization tools (ANTS). OR Insight. 2008;1-35. doi:10.54294\/uvnhin"},{"issue":"2","key":"b39","series-title":"Neuroimage","first-page":"179","article-title":"Cortical surface-based analysis. I. Segmentation and surface reconstruction","volume":"9","author":"Dale\n AM","year":"1999","unstructured":"Dale\n AM\n , FischlB, SerenoMI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194."},{"issue":"3","key":"b40","series-title":"Comput Biomed Res","first-page":"162","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox\n RW","year":"1996","unstructured":"Cox\n RW\n \n . AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res. 1996;29(3):162-173."},{"issue":"1","key":"b41","series-title":"Neuroimage","first-page":"63","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve\n DN","year":"2009","unstructured":"Greve\n DN\n , FischlB. Accurate and robust brain image alignment using boundary-based registration. Neuroimage. 2009;48(1):63-72."},{"issue":"2","key":"b42","series-title":"Neuroimage","first-page":"825","article-title":"Improved optimization for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson\n M","year":"2002","unstructured":"Jenkinson\n M\n , BannisterP, BradyM, SmithS. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage. 2002;17(2):825-841."},{"issue":"1","key":"b43","series-title":"J SIAM Numer Anal","first-page":"76","article-title":"Evaluation of noisy data","volume":"1","author":"Lanczos\n C","year":"1964","unstructured":"Lanczos\n C\n \n . Evaluation of noisy data. J SIAM Numer Anal. 1964;1(1):76-85."},{"issue":"11","key":"b44","series-title":"J Cereb Blood Flow Metab","first-page":"1746","article-title":"Measuring cerebrovascular reactivity: The dynamic response to a step hypercapnic stimulus","volume":"35","author":"Poublanc\n J","year":"2015","unstructured":"Poublanc\n J\n , CrawleyAP, SobczykO, et al.\n Measuring cerebrovascular reactivity: The dynamic response to a step hypercapnic stimulus. J Cereb Blood Flow Metab. 2015;35(11):1746-1756."},{"issue":"9","key":"b45","series-title":"J Neurotrauma","first-page":"789","article-title":"Ambulatory blood pressure monitoring in spinal cord injury: Clinical practicability","volume":"31","author":"Hubli\n M","year":"2014","unstructured":"Hubli\n M\n , KrassioukovAV. Ambulatory blood pressure monitoring in spinal cord injury: Clinical practicability. J Neurotrauma. 2014;31(9):789-797."},{"issue":"18","key":"b46","series-title":"J Neurotrauma","first-page":"2023","article-title":"Intradetrusor onabotulinumtoxinA injections ameliorate autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with cervical and upper thoracic spinal cord injury","volume":"37","author":"Walter\n M","year":"2020","unstructured":"Walter\n M\n , KranSL, RamirezAL, et al.\n Intradetrusor onabotulinumtoxinA injections ameliorate autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with cervical and upper thoracic spinal cord injury. J Neurotrauma. 2020;37(18):2023-2027."},{"issue":"11","key":"b47","series-title":"Spinal Cord","first-page":"1030","article-title":"Heart rate changes associated with autonomic dysreflexia in daily life of individuals with chronic spinal cord injury","volume":"60","author":"Yee\n B","year":"2022","unstructured":"Yee\n B\n , NightingaleTE, RamirezAL, WalterM, KrassioukovAV. Heart rate changes associated with autonomic dysreflexia in daily life of individuals with chronic spinal cord injury. Spinal Cord. 2022;60(11):1030-1036."},{"issue":"9-10","key":"b48","series-title":"J Neurotrauma","first-page":"1020","article-title":"Fesoterodine ameliorates autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with spinal cord injury: A prospective Phase IIa study","volume":"40","author":"Walter\n M","year":"2023","unstructured":"Walter\n M\n , RamirezAL, LeeAHX, et al.\n Fesoterodine ameliorates autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with spinal cord injury: A prospective Phase IIa study. J Neurotrauma. 2023;40(9-10):1020-1025."},{"issue":"4","key":"b49","series-title":"J Spinal Cord Med","first-page":"201","article-title":"International Standards to Document Remaining Autonomic Function after Spinal Cord Injury","volume":"35","author":"Krassioukov\n A","year":"2012","unstructured":"Krassioukov\n A\n , Biering-SorensenF, DonovanW, et al.\n International Standards to Document Remaining Autonomic Function after Spinal Cord Injury. J Spinal Cord Med. 2012;35(4):201-210."},{"issue":"10","key":"b50","series-title":"Am J Hypertens","first-page":"938","article-title":"Blood pressure instability in persons with SCI: Evidence from a 30- day home monitoring observation","volume":"32","author":"Katzelnick\n CG","year":"2019","unstructured":"Katzelnick\n CG\n , WeirJP, JonesA, et al.\n Blood pressure instability in persons with SCI: Evidence from a 30- day home monitoring observation. Am J Hypertens. 2019;32(10):938-944."},{"key":"b51","series-title":"Neuroimage Clin","first-page":"796","article-title":"Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities","volume":"11","author":"Sam\n K","year":"2016","unstructured":"Sam\n K\n , ConklinJ, HolmesKR, et al.\n Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities. Neuroimage Clin. 2016;11:796-801."},{"issue":"3","key":"b52","series-title":"Can J Neurol Sci","first-page":"366","article-title":"Slowed temporal and parietal cerebrovascular response in patients with Alzheimer's disease","volume":"47","author":"Holmes\n KR","year":"2020","unstructured":"Holmes\n KR\n , Tang-WaiD, SamK, et al.\n Slowed temporal and parietal cerebrovascular response in patients with Alzheimer's disease. Can J Neurol Sci. 2020;47(3):366-373."},{"key":"b53","series-title":"Neuroimage","first-page":"207","article-title":"The dynamics of cerebrovascular reactivity shown with transfer function analysis","volume":"114","author":"Duffin\n J","year":"2015","unstructured":"Duffin\n J\n , SobczykO, CrawleyAP, PoublancJ, MikulisDJ, FisherJA. The dynamics of cerebrovascular reactivity shown with transfer function analysis. Neuroimage. 2015;114:207-216."},{"issue":"2","key":"b54","series-title":"Cerebrovasc Brain Metab Rev","first-page":"161","article-title":"Cerebral autoregulation","volume":"2","author":"Paulson\n OB","year":"1990","unstructured":"Paulson\n OB\n , StrandgaardS, EdvinssonL. Cerebral autoregulation. Cerebrovasc Brain Metab Rev. 1990;2(2):161-192."},{"issue":"12","key":"b55","series-title":"J Neurotrauma","first-page":"1713","article-title":"Orthostatic hypotension and autonomic pathways after spinal cord injury","volume":"23","author":"Claydon\n VE","year":"2006","unstructured":"Claydon\n VE\n , KrassioukovAV. Orthostatic hypotension and autonomic pathways after spinal cord injury. J Neurotrauma. 2006;23(12):1713-1725."},{"issue":"2","key":"b56","series-title":"Respir Physiol Neurobiol","first-page":"157","article-title":"Autonomic function following cervical spinal cord injury","volume":"169","author":"Krassioukov\n A","year":"2009","unstructured":"Krassioukov\n A\n \n . Autonomic function following cervical spinal cord injury. Respir Physiol Neurobiol. 2009;169(2):157-164."},{"issue":"6","key":"b57","series-title":"J Physiol","first-page":"1385","article-title":"Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide","volume":"600","author":"Hoiland\n RL","year":"2022","unstructured":"Hoiland\n RL\n , CaldwellHG, CarrJMJR, et al.\n Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide. J Physiol. 2022;600(6):1385-1403."},{"key":"b58","series-title":"Neuroimage","first-page":"110","article-title":"Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive reactivity","volume":"110","author":"Halani\n S","year":"2015","unstructured":"Halani\n S\n , KwintaJB, GolestaniAM, KhatamianYB, ChenJJ. Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive reactivity. Neuroimage. 2015;110:110-123."},{"key":"b59","series-title":"Neuroimage","first-page":"296","article-title":"Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo\/hypercapnia at 7T","volume":"98","author":"Bhogal\n AA","year":"2014","unstructured":"Bhogal\n AA\n , SieroJCW, FisherJA, et al.\n Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo\/hypercapnia at 7T. Neuroimage. 2014;98:296-305."},{"issue":"12","key":"b60","series-title":"Spinal Cord","first-page":"1057","article-title":"Associations between arterial stiffness and blood pressure fluctuations after spinal cord injury","volume":"57","author":"Currie\n KD","year":"2019","unstructured":"Currie\n KD\n , HubliM, MacDonaldMJ, KrassioukovAV. Associations between arterial stiffness and blood pressure fluctuations after spinal cord injury. Spinal Cord. 2019;57(12):1057-1063."},{"issue":"13","key":"b61","series-title":"J Am Coll Cardiol","first-page":"1318","article-title":"Prediction of cardiovascular events and all-cause mortality with arterial stiffness: A systematic review and meta-analysis","volume":"55","author":"Vlachopoulos\n C","year":"2010","unstructured":"Vlachopoulos\n C\n , AznaouridisK, StefanadisC. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: A systematic review and meta-analysis. J Am Coll Cardiol. 2010;55(13):1318-1327."},{"key":"b62","series-title":"Eur J Appl Physiol","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-022-04956-w","article-title":"Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment","author":"Bailey\n TG","year":"2022","unstructured":"Bailey\n TG\n , KleinT, MenesesAL, et al.\n Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment. Eur J Appl Physiol. May2022. doi:10.1007\/s00421-022-04956-w"},{"issue":"5","key":"b63","series-title":"Spinal Cord","first-page":"348","article-title":"The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury","volume":"57","author":"Blight\n AR","year":"2019","unstructured":"Blight\n AR\n , HsiehJ, CurtA, et al.\n The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury. Spinal Cord. 2019;57(5):348-359."},{"key":"b64","series-title":"Maturitas","first-page":"14","article-title":"Sex and gender gap in spinal cord injury research: Focus on cardiometabolic diseases. A mini review","volume":"147","author":"Raguindin\n PF","year":"2021","unstructured":"Raguindin\n PF\n , MukaT, GlisicM. Sex and gender gap in spinal cord injury research: Focus on cardiometabolic diseases. A mini review. Maturitas. 2021;147:14-18."},{"issue":"2","key":"b65","series-title":"Arch Neurol","first-page":"211","article-title":"Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system atrophy","volume":"67","author":"Lipp\n A","year":"2010","unstructured":"Lipp\n A\n , SchmelzerJD, LowPA, JohnsonBD, BenarrochEE. Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system atrophy. Arch Neurol. 2010;67(2):211-216."},{"key":"b66","series-title":"Clin J Sport Med","first-page":"1","article-title":"Intentional induction of autonomic dysreflexia among quadriplegic athletes for performance enhancement: efficacy, safety, and mechanism of action","volume":"4","author":"Burnham\n R","year":"1994","unstructured":"Burnham\n R\n , WheelerG, BhambhaniY, BelangerM. Intentional induction of autonomic dysreflexia among quadriplegic athletes for performance enhancement: efficacy, safety, and mechanism of action. Clin J Sport Med. 1994;4:1-1."},{"issue":"6","key":"b67","series-title":"J Appl Physiol","first-page":"645","article-title":"Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: The effect of midodrine","volume":"116","author":"Phillips\n AA","year":"2014","unstructured":"Phillips\n AA\n , KrassioukovAV, AinsliePN, WarburtonDER. Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: The effect of midodrine. J Appl Physiol. 2014;116(6):645-653."},{"key":"b68","series-title":"Neuroimage","first-page":"118771","article-title":"Medullary vein architecture modulates the white matter BOLD cerebrovascular reactivity signal response to CO2: Observations from high-resolution T2* weighted imaging at 7T","volume":"245","author":"Bhogal\n AA","year":"2021","unstructured":"Bhogal\n AA\n \n . Medullary vein architecture modulates the white matter BOLD cerebrovascular reactivity signal response to CO2: Observations from high-resolution T2* weighted imaging at 7T. Neuroimage. 2021;245:118771."},{"issue":"1","key":"b69","series-title":"Sci Rep","first-page":"4405","article-title":"A national survey of physical activity after spinal cord injury","volume":"12","author":"Soriano\n JE","year":"2022","unstructured":"Soriano\n JE\n , SquairJW, CraggJJ, et al.\n A national survey of physical activity after spinal cord injury. Sci Rep. 2022;12(1):4405."},{"issue":"3","key":"b70","series-title":"Top Spinal Cord Inj Rehabil","first-page":"175","article-title":"Exercise and health-related risks of physical deconditioning after spinal cord injury","volume":"23","author":"Maher\n JL","year":"2017","unstructured":"Maher\n JL\n , McMillanDW, NashMS. Exercise and health-related risks of physical deconditioning after spinal cord injury. Top Spinal Cord Inj Rehabil. 2017;23(3):175-187."},{"issue":"1","key":"b71","series-title":"Brain Plast","first-page":"65","article-title":"Exercise improves vascular function, but does this translate to the brain?","volume":"4","author":"Barnes\n JN","year":"2018","unstructured":"Barnes\n JN\n , CorkeryAT. Exercise improves vascular function, but does this translate to the brain?Brain Plast. 2018;4(1):65-79."},{"issue":"21","key":"b72","series-title":"Neurology","first-page":"e2245","article-title":"Aerobic exercise improves cognition and cerebrovascular regulation in older adults","volume":"94","author":"Guadagni\n V","year":"2020","unstructured":"Guadagni\n V\n , DrogosLL, TyndallAV, et al.\n Aerobic exercise improves cognition and cerebrovascular regulation in older adults. Neurology. 2020;94(21):e2245-e2257."},{"key":"b73","series-title":"Front Physiol","first-page":"998380","article-title":"Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies","volume":"13","author":"Daniele\n A","year":"2022","unstructured":"Daniele\n A\n , LucasSJE, RendeiroC. Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies. Front Physiol. 2022;13:998380."},{"issue":"4","key":"b74","series-title":"J Spinal Cord Med","first-page":"374","article-title":"Sleep disordered breathing in spinal cord injury: A systematic review","volume":"39","author":"Chiodo\n AE","year":"2016","unstructured":"Chiodo\n AE\n , SitrinRG, BaumanKA. Sleep disordered breathing in spinal cord injury: A systematic review. J Spinal Cord Med. 2016;39(4):374-382."},{"issue":"5","key":"b75","series-title":"Arch Phys Med Rehabil","first-page":"1034","article-title":"Is sleep disordered breathing confounding rehabilitation outcomes in spinal cord injury research?","volume":"103","author":"Panza\n GS","year":"2022","unstructured":"Panza\n GS\n , SutorT, GeeCM, et al.\n Is sleep disordered breathing confounding rehabilitation outcomes in spinal cord injury research?\n Arch Phys Med Rehabil. 2022;103(5):1034-1045."},{"issue":"24","key":"b76","series-title":"Neurology","first-page":"e2181","article-title":"Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury","volume":"93","author":"Squair\n JW","year":"2019","unstructured":"Squair\n JW\n , LeeAHX, SarafisZK, et al.\n Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury. Neurology. 2019;93(24):e2181-e2191."},{"issue":"6","key":"b77","series-title":"J Cereb Blood Flow Metab","first-page":"1328","article-title":"MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea","volume":"40","author":"Wu\n PH","year":"2020","unstructured":"Wu\n PH\n , Rodriguez-SotoAE, RodgersZB, et al.\n MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea. J Cereb Blood Flow Metab. 2020;40(6):1328-1337."},{"key":"b78","series-title":"Front Physiol","first-page":"668662","article-title":"The reproducibility of cerebrovascular reactivity across MRI scanners","volume":"12","author":"Sobczyk\n O","year":"2021","unstructured":"Sobczyk\n O\n , SayinES, SamK, et al.\n The reproducibility of cerebrovascular reactivity across MRI scanners. Front Physiol. 2021;12:668662."},{"key":"b79","series-title":"Neuroimage","first-page":"118754","article-title":"Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge","volume":"245","author":"Liu\n P","year":"2021","unstructured":"Liu\n P\n , JiangD, AlbertM, et al.\n Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge. Neuroimage. 2021;245:118754."},{"issue":"8","key":"b1","series-title":"Neurology","first-page":"723","article-title":"Cardiovascular disease and spinal cord injury: Results from a national population health survey","volume":"81","author":"Cragg\n JJ","year":"2013","unstructured":"Cragg\n JJ\n , NoonanVK, KrassioukovA, BorisoffJ. Cardiovascular disease and spinal cord injury: Results from a national population health survey. Neurology. 2013;81(8):723-728."},{"issue":"14","key":"b2","series-title":"Neurology","first-page":"1051","article-title":"Increased risk of stroke after spinal cord injury: A nationwide 4-year follow-up cohort study","volume":"78","author":"Wu\n JC","year":"2012","unstructured":"Wu\n JC\n , ChenYC, LiuL, et al.\n Increased risk of stroke after spinal cord injury: A nationwide 4-year follow-up cohort study. Neurology. 2012;78(14):1051-1057."},{"issue":"13","key":"b3","series-title":"Neurology","first-page":"611","article-title":"Cognitive function after spinal cord injury: A systematic review","volume":"91","author":"Sachdeva\n R","year":"2018","unstructured":"Sachdeva\n R\n , GaoF, ChanCCH, KrassioukovAV. Cognitive function after spinal cord injury: A systematic review. Neurology. 2018;91(13):611-621."},{"issue":"10","key":"b4","series-title":"Int J Mol Sci","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20102464","article-title":"The blood pressure pendulum following spinal cord injury: Implications for vascular cognitive impairment","volume":"20","author":"Sachdeva\n R","year":"2019","unstructured":"Sachdeva\n R\n , NightingaleTE, KrassioukovAV. The blood pressure pendulum following spinal cord injury: Implications for vascular cognitive impairment. Int J Mol Sci. 2019;20(10). doi:10.3390\/ijms20102464"},{"key":"b5","series-title":"Auton Neurosci","first-page":"43","article-title":"Alterations in autonomic cerebrovascular control after spinal cord injury","volume":"209","author":"Kim\n DI","year":"2018","unstructured":"Kim\n DI\n , TanCO. Alterations in autonomic cerebrovascular control after spinal cord injury. Auton Neurosci. 2018;209:43-50."},{"issue":"24","key":"b6","series-title":"J Neurotrauma","first-page":"1927","article-title":"Contemporary cardiovascular concerns after spinal cord injury: Mechanisms, maladaptations, and management","volume":"32","author":"Phillips\n AA","year":"2015","unstructured":"Phillips\n AA\n , KrassioukovAV. Contemporary cardiovascular concerns after spinal cord injury: Mechanisms, maladaptations, and management. J Neurotrauma. 2015;32(24):1927-1942."},{"issue":"5","key":"b7","series-title":"Semin Neurol","first-page":"550","article-title":"Cardiovascular autonomic dysfunction in spinal cord injury: Epidemiology, diagnosis, and management","volume":"40","author":"Wecht\n JM","year":"2020","unstructured":"Wecht\n JM\n , HarelNY, GuestJ, et al.\n Cardiovascular autonomic dysfunction in spinal cord injury: Epidemiology, diagnosis, and management. Semin Neurol. 2020;40(5):550-559."},{"issue":"5","key":"b8","series-title":"J Physiol","first-page":"841","article-title":"Integrative regulation of human brain blood flow","volume":"592","author":"Willie\n CK","year":"2014","unstructured":"Willie\n CK\n , TzengYC, FisherJA, AinsliePN. Integrative regulation of human brain blood flow. J Physiol. 2014;592(5):841-859."},{"issue":"3","key":"b9","series-title":"Hypertension","first-page":"698","article-title":"Influence of changes in blood pressure on cerebral perfusion and oxygenation","volume":"55","author":"Lucas\n SJE","year":"2010","unstructured":"Lucas\n SJE\n , TzengYC, GalvinSD, ThomasKN, OgohS, AinsliePN. Influence of changes in blood pressure on cerebral perfusion and oxygenation. Hypertension. 2010;55(3):698-705."},{"issue":"4","key":"b10","series-title":"J Spinal Cord Med","first-page":"606","article-title":"PRES secondary to autonomic dysreflexia: A case series and review of the literature","volume":"44","author":"Hubbard\n ME","year":"2021","unstructured":"Hubbard\n ME\n , PhillipsAA, CharbonneauR, SquairJW, ParrAM, KrassioukovA. PRES secondary to autonomic dysreflexia: A case series and review of the literature. J Spinal Cord Med. 2021;44(4):606-612."},{"issue":"1","key":"b11","series-title":"J Spinal Cord Med","first-page":"2","article-title":"Life-threatening outcomes associated with autonomic dysreflexia: A clinical review","volume":"37","author":"Wan\n D","year":"2014","unstructured":"Wan\n D\n , KrassioukovAV. Life-threatening outcomes associated with autonomic dysreflexia: A clinical review. J Spinal Cord Med. 2014;37(1):2-10."},{"issue":"18","key":"b12","series-title":"J Neurotrauma","first-page":"1963","article-title":"Vascular-cognitive impairment following high-thoracic spinal cord injury is associated with structural and functional maladaptations in cerebrovasculature","volume":"37","author":"Sachdeva\n R","year":"2020","unstructured":"Sachdeva\n R\n , JiaM, WangS, et al.\n Vascular-cognitive impairment following high-thoracic spinal cord injury is associated with structural and functional maladaptations in cerebrovasculature. J Neurotrauma. 2020;37(18):1963-1970."},{"issue":"3","key":"b13","series-title":"J Neurotrauma","first-page":"573","article-title":"Transient hypertension after spinal cord injury leads to cerebrovascular endothelial dysfunction and fibrosis","volume":"35","author":"Phillips\n AA","year":"2018","unstructured":"Phillips\n AA\n , MatinN, JiaM, et al.\n Transient hypertension after spinal cord injury leads to cerebrovascular endothelial dysfunction and fibrosis. J Neurotrauma. 2018;35(3):573-581."},{"issue":"9735","key":"b14","series-title":"Lancet","first-page":"112","article-title":"Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study","volume":"376","author":"O'Donnell\n MJ","year":"2010","unstructured":"O'Donnell\n MJ\n , XavierD, LiuL, et al.\n Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. Lancet. 2010;376(9735):112-123."},{"key":"b15","series-title":"Nat Rev Dis Primers","first-page":"18003","article-title":"Vascular cognitive impairment","volume":"4","author":"van der Flier\n WM","year":"2018","unstructured":"van der Flier\n WM\n , SkoogI, SchneiderJA, et al.\n Vascular cognitive impairment. Nat Rev Dis Primers. 2018;4:18003."},{"issue":"Pt 3","key":"b16","series-title":"Brain","first-page":"457","article-title":"Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion","volume":"124","author":"Markus\n H","year":"2001","unstructured":"Markus\n H\n , CullinaneM. Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion. Brain. 2001;124(Pt 3):457-467."},{"key":"b17","series-title":"J Exp Neurosci","first-page":"1179069518785151","article-title":"Regional cerebrovascular reactivity and cognitive performance in healthy aging","volume":"12","author":"Catchlove\n SJ","year":"2018","unstructured":"Catchlove\n SJ\n , ParrishTB, ChenY, MacphersonH, HughesME, PipingasA. Regional cerebrovascular reactivity and cognitive performance in healthy aging. J Exp Neurosci. 2018;12:1179069518785151."},{"issue":"23","key":"b18","series-title":"J Physiol","first-page":"5809","article-title":"Measuring cerebrovascular reactivity: What stimulus to use?","volume":"591","author":"Fierstra\n J","year":"2013","unstructured":"Fierstra\n J\n , SobczykO, Battisti-CharbonneyA, et al.\n Measuring cerebrovascular reactivity: What stimulus to use?\n J Physiol. 2013;591(23):5809-5821."},{"key":"b19","series-title":"Front Physiol","first-page":"629651","article-title":"Cerebrovascular reactivity: Purpose, optimizing methods, and limitations to interpretation - A personal 20-year odyssey of (re) searching","volume":"12","author":"Fisher\n JA","year":"2021","unstructured":"Fisher\n JA\n , MikulisDJ. Cerebrovascular reactivity: Purpose, optimizing methods, and limitations to interpretation - A personal 20-year odyssey of (re) searching. Front Physiol. 2021;12:629651."},{"issue":"5","key":"b20","series-title":"J Cereb Blood Flow Metab","first-page":"794","article-title":"Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: Improved by alpha-1 agonist midodrine hydrochloride","volume":"34","author":"Phillips\n AA","year":"2014","unstructured":"Phillips\n AA\n , WarburtonDER, AinsliePN, KrassioukovAV. Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: Improved by alpha-1 agonist midodrine hydrochloride. J Cereb Blood Flow Metab. 2014;34(5):794-801."},{"issue":"7775","key":"b21","series-title":"Lancet","first-page":"457","article-title":"Absence of cerebral vasoconstriction with hyperventilation in tetraplegic man. Evidence for neurogenic control of cerebral circulation","volume":"2","author":"Eidelman\n BH","year":"1972","unstructured":"Eidelman\n BH\n , DebargeO, CorbettJL, FrankelH. Absence of cerebral vasoconstriction with hyperventilation in tetraplegic man. Evidence for neurogenic control of cerebral circulation. Lancet. 1972;2(7775):457-460."},{"issue":"1","key":"b22","series-title":"J Neurol Sci","first-page":"129","article-title":"The effect of hypocapnia and change of blood pressure on cerebral blood flow in men with cervical spinal cord transection","volume":"30","author":"Nanda\n RN","year":"1976","unstructured":"Nanda\n RN\n , WyperDJ, JohnsonRH, HarperAM. The effect of hypocapnia and change of blood pressure on cerebral blood flow in men with cervical spinal cord transection. J Neurol Sci. 1976;30(1):129-135."},{"issue":"4","key":"b23","series-title":"Am J Physiol Regul Integr Comp Physiol","first-page":"R1035","article-title":"Cerebrovascular reactivity and dynamic autoregulation in tetraplegia","volume":"298","author":"Wilson\n LC","year":"2010","unstructured":"Wilson\n LC\n , CotterJD, FanJL, LucasRAI, ThomasKN, AinsliePN. Cerebrovascular reactivity and dynamic autoregulation in tetraplegia. Am J Physiol Regul Integr Comp Physiol. 2010;298(4):R1035-R1042."},{"key":"b24","series-title":"Front Physiol","first-page":"656746","article-title":"Contrasting measures of cerebrovascular reactivity between MRI and Doppler: A cross-sectional study of younger and older healthy individuals","volume":"12","author":"Burley\n CV","year":"2021","unstructured":"Burley\n CV\n , FrancisST, ThomasKN, WhittakerAC, LucasSJE, MullingerKJ. Contrasting measures of cerebrovascular reactivity between MRI and Doppler: A cross-sectional study of younger and older healthy individuals. Front Physiol. 2021;12:656746."},{"key":"b25","series-title":"Front Physiol","first-page":"665049","article-title":"Measuring cerebrovascular reactivity: Sixteen avoidable pitfalls","volume":"12","author":"Sobczyk\n O","year":"2021","unstructured":"Sobczyk\n O\n , FierstraJ, VenkatraghavanL, et al.\n Measuring cerebrovascular reactivity: Sixteen avoidable pitfalls. Front Physiol. 2021;12:665049."},{"issue":"8","key":"b26","series-title":"Stroke","first-page":"2011","article-title":"Magnetic resonance imaging-based cerebrovascular reactivity and hemodynamic reserve","volume":"49","author":"Fisher\n JA","year":"2018","unstructured":"Fisher\n JA\n , VenkatraghavanL, MikulisDJ. Magnetic resonance imaging-based cerebrovascular reactivity and hemodynamic reserve. Stroke. 2018;49(8):2011-2018."},{"issue":"3","key":"b27","series-title":"Proc Natl Acad Sci USA","first-page":"1753","article-title":"Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice","volume":"17","author":"Wenzel\n J","year":"2020","unstructured":"Wenzel\n J\n , HansenCE, BettoniC, et al.\n Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice. Proc Natl Acad Sci USA. 2020;117(3):1753-1761."},{"issue":"6","key":"b28","series-title":"J Cereb Blood Flow Metab","first-page":"1004","article-title":"The CO2 stimulus for cerebrovascular reactivity: Fixing inspired concentrations vs. targeting end-tidal partial pressures","volume":"36","author":"Fisher\n JA","year":"2016","unstructured":"Fisher\n JA\n \n . The CO2 stimulus for cerebrovascular reactivity: Fixing inspired concentrations vs. targeting end-tidal partial pressures. J Cereb Blood Flow Metab. 2016;36(6):1004-1011."},{"issue":"9","key":"b29","series-title":"J Cereb Blood Flow Metab","first-page":"1042","article-title":"Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response","volume":"22","author":"Cohen\n ER","year":"2002","unstructured":"Cohen\n ER\n , UgurbilK, KimSG. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J Cereb Blood Flow Metab. 2002;22(9):1042-1053."},{"issue":"4","key":"b30","series-title":"Neuroimage","first-page":"1642","article-title":"Vascular dynamics and BOLD fMRI: CBF level effects and analysis considerations","volume":"32","author":"Vazquez\n AL","year":"2006","unstructured":"Vazquez\n AL\n , CohenER, GulaniV, et al.\n Vascular dynamics and BOLD fMRI: CBF level effects and analysis considerations. Neuroimage. 2006;32(4):1642-1655."},{"issue":"2","key":"b31","series-title":"Neuroimage","first-page":"579","article-title":"Impaired cerebral vasoreactivity to CO2 in Alzheimer's disease using BOLD fMRI","volume":"58","author":"Cantin\n S","year":"2011","unstructured":"Cantin\n S\n , VillienM, MoreaudO, et al.\n Impaired cerebral vasoreactivity to CO2 in Alzheimer's disease using BOLD fMRI. Neuroimage. 2011;58(2):579-587."},{"issue":"6","key":"b32","series-title":"J Spinal Cord Med","first-page":"535","article-title":"International Standards for Neurological Classification of Spinal Cord Injury (revised 2011)","volume":"34","author":"Kirshblum\n SC","year":"2011","unstructured":"Kirshblum\n SC\n , BurnsSP, Biering-SorensenF, et al.\n International Standards for Neurological Classification of Spinal Cord Injury (revised 2011). J Spinal Cord Med. 2011;34(6):535-546."},{"issue":"9","key":"b33","series-title":"Magn Reson Imaging","first-page":"995","article-title":"Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions","volume":"21","author":"Brevard\n ME","year":"2003","unstructured":"Brevard\n ME\n , DuongTQ, KingJA, FerrisCF. Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions. Magn Reson Imaging. 2003;21(9):995-1001."},{"issue":"2","key":"b34","series-title":"Neuroimage","first-page":"87","article-title":"Regional differences in the CBF and BOLD responses to hypercapnia: A combined PET and fMRI study","volume":"11","author":"Rostrup\n E","year":"2000","unstructured":"Rostrup\n E\n , LawI, BlinkenbergM, et al.\n Regional differences in the CBF and BOLD responses to hypercapnia: A combined PET and fMRI study. Neuroimage. 2000;11(2):87-97."},{"issue":"6","key":"b35","series-title":"J Cereb Blood Flow Metab","first-page":"1036","article-title":"Safety of hypercapnic challenge: Cardiovascular and neurologic considerations","volume":"11","author":"Gitelman\n DR","year":"1991","unstructured":"Gitelman\n DR\n , ProhovnikI, TatemichiTK. Safety of hypercapnic challenge: Cardiovascular and neurologic considerations. J Cereb Blood Flow Metab. 1991;11(6):1036-1040."},{"key":"b36","series-title":"Poldracklab\/fmriprep: 1.0.0-rc5","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.996169","author":"Esteban\n O","year":"2017","unstructured":"Esteban\n O\n , BlairR, MarkiewiczCJ, et al.\n Poldracklab\/fmriprep: 1.0.0-rc5. 2017. doi:10.5281\/zenodo.996169"},{"issue":"2","key":"b37","series-title":"Neuroimage","first-page":"782","article-title":"FSL","volume":"62","author":"Jenkinson\n M","year":"2012","unstructured":"Jenkinson\n M\n , BeckmannCF, BehrensTEJ, WoolrichMW, SmithSM. FSL. Neuroimage. 2012;62(2):782-790."},{"key":"b38","series-title":"OR Insight","doi-asserted-by":"publisher","first-page":"1","DOI":"10.54294\/uvnhin","article-title":"Advanced normalization tools (ANTS)","author":"Avants\n BB","year":"2008","unstructured":"Avants\n BB\n , TustisonN, SongG. Advanced normalization tools (ANTS). OR Insight. 2008;1-35. doi:10.54294\/uvnhin"},{"issue":"2","key":"b39","series-title":"Neuroimage","first-page":"179","article-title":"Cortical surface-based analysis. I. Segmentation and surface reconstruction","volume":"9","author":"Dale\n AM","year":"1999","unstructured":"Dale\n AM\n , FischlB, SerenoMI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage. 1999;9(2):179-194."},{"issue":"3","key":"b40","series-title":"Comput Biomed Res","first-page":"162","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox\n RW","year":"1996","unstructured":"Cox\n RW\n \n . AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res. 1996;29(3):162-173."},{"issue":"1","key":"b41","series-title":"Neuroimage","first-page":"63","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"Greve\n DN","year":"2009","unstructured":"Greve\n DN\n , FischlB. Accurate and robust brain image alignment using boundary-based registration. Neuroimage. 2009;48(1):63-72."},{"issue":"2","key":"b42","series-title":"Neuroimage","first-page":"825","article-title":"Improved optimization for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson\n M","year":"2002","unstructured":"Jenkinson\n M\n , BannisterP, BradyM, SmithS. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage. 2002;17(2):825-841."},{"issue":"1","key":"b43","series-title":"J SIAM Numer Anal","first-page":"76","article-title":"Evaluation of noisy data","volume":"1","author":"Lanczos\n C","year":"1964","unstructured":"Lanczos\n C\n \n . Evaluation of noisy data. J SIAM Numer Anal. 1964;1(1):76-85."},{"issue":"11","key":"b44","series-title":"J Cereb Blood Flow Metab","first-page":"1746","article-title":"Measuring cerebrovascular reactivity: The dynamic response to a step hypercapnic stimulus","volume":"35","author":"Poublanc\n J","year":"2015","unstructured":"Poublanc\n J\n , CrawleyAP, SobczykO, et al.\n Measuring cerebrovascular reactivity: The dynamic response to a step hypercapnic stimulus. J Cereb Blood Flow Metab. 2015;35(11):1746-1756."},{"issue":"9","key":"b45","series-title":"J Neurotrauma","first-page":"789","article-title":"Ambulatory blood pressure monitoring in spinal cord injury: Clinical practicability","volume":"31","author":"Hubli\n M","year":"2014","unstructured":"Hubli\n M\n , KrassioukovAV. Ambulatory blood pressure monitoring in spinal cord injury: Clinical practicability. J Neurotrauma. 2014;31(9):789-797."},{"issue":"18","key":"b46","series-title":"J Neurotrauma","first-page":"2023","article-title":"Intradetrusor onabotulinumtoxinA injections ameliorate autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with cervical and upper thoracic spinal cord injury","volume":"37","author":"Walter\n M","year":"2020","unstructured":"Walter\n M\n , KranSL, RamirezAL, et al.\n Intradetrusor onabotulinumtoxinA injections ameliorate autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with cervical and upper thoracic spinal cord injury. J Neurotrauma. 2020;37(18):2023-2027."},{"issue":"11","key":"b47","series-title":"Spinal Cord","first-page":"1030","article-title":"Heart rate changes associated with autonomic dysreflexia in daily life of individuals with chronic spinal cord injury","volume":"60","author":"Yee\n B","year":"2022","unstructured":"Yee\n B\n , NightingaleTE, RamirezAL, WalterM, KrassioukovAV. Heart rate changes associated with autonomic dysreflexia in daily life of individuals with chronic spinal cord injury. Spinal Cord. 2022;60(11):1030-1036."},{"issue":"9-10","key":"b48","series-title":"J Neurotrauma","first-page":"1020","article-title":"Fesoterodine ameliorates autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with spinal cord injury: A prospective Phase IIa study","volume":"40","author":"Walter\n M","year":"2023","unstructured":"Walter\n M\n , RamirezAL, LeeAHX, et al.\n Fesoterodine ameliorates autonomic dysreflexia while improving lower urinary tract function and urinary incontinence-related quality of life in individuals with spinal cord injury: A prospective Phase IIa study. J Neurotrauma. 2023;40(9-10):1020-1025."},{"issue":"4","key":"b49","series-title":"J Spinal Cord Med","first-page":"201","article-title":"International Standards to Document Remaining Autonomic Function after Spinal Cord Injury","volume":"35","author":"Krassioukov\n A","year":"2012","unstructured":"Krassioukov\n A\n , Biering-SorensenF, DonovanW, et al.\n International Standards to Document Remaining Autonomic Function after Spinal Cord Injury. J Spinal Cord Med. 2012;35(4):201-210."},{"issue":"10","key":"b50","series-title":"Am J Hypertens","first-page":"938","article-title":"Blood pressure instability in persons with SCI: Evidence from a 30- day home monitoring observation","volume":"32","author":"Katzelnick\n CG","year":"2019","unstructured":"Katzelnick\n CG\n , WeirJP, JonesA, et al.\n Blood pressure instability in persons with SCI: Evidence from a 30- day home monitoring observation. Am J Hypertens. 2019;32(10):938-944."},{"key":"b51","series-title":"Neuroimage Clin","first-page":"796","article-title":"Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities","volume":"11","author":"Sam\n K","year":"2016","unstructured":"Sam\n K\n , ConklinJ, HolmesKR, et al.\n Impaired dynamic cerebrovascular response to hypercapnia predicts development of white matter hyperintensities. Neuroimage Clin. 2016;11:796-801."},{"issue":"3","key":"b52","series-title":"Can J Neurol Sci","first-page":"366","article-title":"Slowed temporal and parietal cerebrovascular response in patients with Alzheimer's disease","volume":"47","author":"Holmes\n KR","year":"2020","unstructured":"Holmes\n KR\n , Tang-WaiD, SamK, et al.\n Slowed temporal and parietal cerebrovascular response in patients with Alzheimer's disease. Can J Neurol Sci. 2020;47(3):366-373."},{"key":"b53","series-title":"Neuroimage","first-page":"207","article-title":"The dynamics of cerebrovascular reactivity shown with transfer function analysis","volume":"114","author":"Duffin\n J","year":"2015","unstructured":"Duffin\n J\n , SobczykO, CrawleyAP, PoublancJ, MikulisDJ, FisherJA. The dynamics of cerebrovascular reactivity shown with transfer function analysis. Neuroimage. 2015;114:207-216."},{"issue":"2","key":"b54","series-title":"Cerebrovasc Brain Metab Rev","first-page":"161","article-title":"Cerebral autoregulation","volume":"2","author":"Paulson\n OB","year":"1990","unstructured":"Paulson\n OB\n , StrandgaardS, EdvinssonL. Cerebral autoregulation. Cerebrovasc Brain Metab Rev. 1990;2(2):161-192."},{"issue":"12","key":"b55","series-title":"J Neurotrauma","first-page":"1713","article-title":"Orthostatic hypotension and autonomic pathways after spinal cord injury","volume":"23","author":"Claydon\n VE","year":"2006","unstructured":"Claydon\n VE\n , KrassioukovAV. Orthostatic hypotension and autonomic pathways after spinal cord injury. J Neurotrauma. 2006;23(12):1713-1725."},{"issue":"2","key":"b56","series-title":"Respir Physiol Neurobiol","first-page":"157","article-title":"Autonomic function following cervical spinal cord injury","volume":"169","author":"Krassioukov\n A","year":"2009","unstructured":"Krassioukov\n A\n \n . Autonomic function following cervical spinal cord injury. Respir Physiol Neurobiol. 2009;169(2):157-164."},{"issue":"6","key":"b57","series-title":"J Physiol","first-page":"1385","article-title":"Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide","volume":"600","author":"Hoiland\n RL","year":"2022","unstructured":"Hoiland\n RL\n , CaldwellHG, CarrJMJR, et al.\n Nitric oxide contributes to cerebrovascular shear-mediated dilatation but not steady-state cerebrovascular reactivity to carbon dioxide. J Physiol. 2022;600(6):1385-1403."},{"key":"b58","series-title":"Neuroimage","first-page":"110","article-title":"Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive reactivity","volume":"110","author":"Halani\n S","year":"2015","unstructured":"Halani\n S\n , KwintaJB, GolestaniAM, KhatamianYB, ChenJJ. Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive reactivity. Neuroimage. 2015;110:110-123."},{"key":"b59","series-title":"Neuroimage","first-page":"296","article-title":"Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo\/hypercapnia at 7T","volume":"98","author":"Bhogal\n AA","year":"2014","unstructured":"Bhogal\n AA\n , SieroJCW, FisherJA, et al.\n Investigating the non-linearity of the BOLD cerebrovascular reactivity response to targeted hypo\/hypercapnia at 7T. Neuroimage. 2014;98:296-305."},{"issue":"12","key":"b60","series-title":"Spinal Cord","first-page":"1057","article-title":"Associations between arterial stiffness and blood pressure fluctuations after spinal cord injury","volume":"57","author":"Currie\n KD","year":"2019","unstructured":"Currie\n KD\n , HubliM, MacDonaldMJ, KrassioukovAV. Associations between arterial stiffness and blood pressure fluctuations after spinal cord injury. Spinal Cord. 2019;57(12):1057-1063."},{"issue":"13","key":"b61","series-title":"J Am Coll Cardiol","first-page":"1318","article-title":"Prediction of cardiovascular events and all-cause mortality with arterial stiffness: A systematic review and meta-analysis","volume":"55","author":"Vlachopoulos\n C","year":"2010","unstructured":"Vlachopoulos\n C\n , AznaouridisK, StefanadisC. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: A systematic review and meta-analysis. J Am Coll Cardiol. 2010;55(13):1318-1327."},{"key":"b62","series-title":"Eur J Appl Physiol","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-022-04956-w","article-title":"Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment","author":"Bailey\n TG","year":"2022","unstructured":"Bailey\n TG\n , KleinT, MenesesAL, et al.\n Cerebrovascular function and its association with systemic artery function and stiffness in older adults with and without mild cognitive impairment. Eur J Appl Physiol. May2022. doi:10.1007\/s00421-022-04956-w"},{"issue":"5","key":"b63","series-title":"Spinal Cord","first-page":"348","article-title":"The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury","volume":"57","author":"Blight\n AR","year":"2019","unstructured":"Blight\n AR\n , HsiehJ, CurtA, et al.\n The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury. Spinal Cord. 2019;57(5):348-359."},{"key":"b64","series-title":"Maturitas","first-page":"14","article-title":"Sex and gender gap in spinal cord injury research: Focus on cardiometabolic diseases. A mini review","volume":"147","author":"Raguindin\n PF","year":"2021","unstructured":"Raguindin\n PF\n , MukaT, GlisicM. Sex and gender gap in spinal cord injury research: Focus on cardiometabolic diseases. A mini review. Maturitas. 2021;147:14-18."},{"issue":"2","key":"b65","series-title":"Arch Neurol","first-page":"211","article-title":"Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system atrophy","volume":"67","author":"Lipp\n A","year":"2010","unstructured":"Lipp\n A\n , SchmelzerJD, LowPA, JohnsonBD, BenarrochEE. Ventilatory and cardiovascular responses to hypercapnia and hypoxia in multiple-system atrophy. Arch Neurol. 2010;67(2):211-216."},{"key":"b66","series-title":"Clin J Sport Med","first-page":"1","article-title":"Intentional induction of autonomic dysreflexia among quadriplegic athletes for performance enhancement: efficacy, safety, and mechanism of action","volume":"4","author":"Burnham\n R","year":"1994","unstructured":"Burnham\n R\n , WheelerG, BhambhaniY, BelangerM. Intentional induction of autonomic dysreflexia among quadriplegic athletes for performance enhancement: efficacy, safety, and mechanism of action. Clin J Sport Med. 1994;4:1-1."},{"issue":"6","key":"b67","series-title":"J Appl Physiol","first-page":"645","article-title":"Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: The effect of midodrine","volume":"116","author":"Phillips\n AA","year":"2014","unstructured":"Phillips\n AA\n , KrassioukovAV, AinsliePN, WarburtonDER. Perturbed and spontaneous regional cerebral blood flow responses to changes in blood pressure after high-level spinal cord injury: The effect of midodrine. J Appl Physiol. 2014;116(6):645-653."},{"key":"b68","series-title":"Neuroimage","first-page":"118771","article-title":"Medullary vein architecture modulates the white matter BOLD cerebrovascular reactivity signal response to CO2: Observations from high-resolution T2* weighted imaging at 7T","volume":"245","author":"Bhogal\n AA","year":"2021","unstructured":"Bhogal\n AA\n \n . Medullary vein architecture modulates the white matter BOLD cerebrovascular reactivity signal response to CO2: Observations from high-resolution T2* weighted imaging at 7T. Neuroimage. 2021;245:118771."},{"issue":"1","key":"b69","series-title":"Sci Rep","first-page":"4405","article-title":"A national survey of physical activity after spinal cord injury","volume":"12","author":"Soriano\n JE","year":"2022","unstructured":"Soriano\n JE\n , SquairJW, CraggJJ, et al.\n A national survey of physical activity after spinal cord injury. Sci Rep. 2022;12(1):4405."},{"issue":"3","key":"b70","series-title":"Top Spinal Cord Inj Rehabil","first-page":"175","article-title":"Exercise and health-related risks of physical deconditioning after spinal cord injury","volume":"23","author":"Maher\n JL","year":"2017","unstructured":"Maher\n JL\n , McMillanDW, NashMS. Exercise and health-related risks of physical deconditioning after spinal cord injury. Top Spinal Cord Inj Rehabil. 2017;23(3):175-187."},{"issue":"1","key":"b71","series-title":"Brain Plast","first-page":"65","article-title":"Exercise improves vascular function, but does this translate to the brain?","volume":"4","author":"Barnes\n JN","year":"2018","unstructured":"Barnes\n JN\n , CorkeryAT. Exercise improves vascular function, but does this translate to the brain?Brain Plast. 2018;4(1):65-79."},{"issue":"21","key":"b72","series-title":"Neurology","first-page":"e2245","article-title":"Aerobic exercise improves cognition and cerebrovascular regulation in older adults","volume":"94","author":"Guadagni\n V","year":"2020","unstructured":"Guadagni\n V\n , DrogosLL, TyndallAV, et al.\n Aerobic exercise improves cognition and cerebrovascular regulation in older adults. Neurology. 2020;94(21):e2245-e2257."},{"key":"b73","series-title":"Front Physiol","first-page":"998380","article-title":"Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies","volume":"13","author":"Daniele\n A","year":"2022","unstructured":"Daniele\n A\n , LucasSJE, RendeiroC. Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies. Front Physiol. 2022;13:998380."},{"issue":"4","key":"b74","series-title":"J Spinal Cord Med","first-page":"374","article-title":"Sleep disordered breathing in spinal cord injury: A systematic review","volume":"39","author":"Chiodo\n AE","year":"2016","unstructured":"Chiodo\n AE\n , SitrinRG, BaumanKA. Sleep disordered breathing in spinal cord injury: A systematic review. J Spinal Cord Med. 2016;39(4):374-382."},{"issue":"5","key":"b75","series-title":"Arch Phys Med Rehabil","first-page":"1034","article-title":"Is sleep disordered breathing confounding rehabilitation outcomes in spinal cord injury research?","volume":"103","author":"Panza\n GS","year":"2022","unstructured":"Panza\n GS\n , SutorT, GeeCM, et al.\n Is sleep disordered breathing confounding rehabilitation outcomes in spinal cord injury research?\n Arch Phys Med Rehabil. 2022;103(5):1034-1045."},{"issue":"24","key":"b76","series-title":"Neurology","first-page":"e2181","article-title":"Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury","volume":"93","author":"Squair\n JW","year":"2019","unstructured":"Squair\n JW\n , LeeAHX, SarafisZK, et al.\n Sleep-disordered breathing is associated with brain vascular reactivity in spinal cord injury. Neurology. 2019;93(24):e2181-e2191."},{"issue":"6","key":"b77","series-title":"J Cereb Blood Flow Metab","first-page":"1328","article-title":"MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea","volume":"40","author":"Wu\n PH","year":"2020","unstructured":"Wu\n PH\n , Rodriguez-SotoAE, RodgersZB, et al.\n MRI evaluation of cerebrovascular reactivity in obstructive sleep apnea. J Cereb Blood Flow Metab. 2020;40(6):1328-1337."},{"key":"b78","series-title":"Front Physiol","first-page":"668662","article-title":"The reproducibility of cerebrovascular reactivity across MRI scanners","volume":"12","author":"Sobczyk\n O","year":"2021","unstructured":"Sobczyk\n O\n , SayinES, SamK, et al.\n The reproducibility of cerebrovascular reactivity across MRI scanners. Front Physiol. 2021;12:668662."},{"key":"b79","series-title":"Neuroimage","first-page":"118754","article-title":"Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge","volume":"245","author":"Liu\n P","year":"2021","unstructured":"Liu\n P\n , JiangD, AlbertM, et al.\n Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge. Neuroimage. 2021;245:118754."}],"container-title":["Topics in Spinal Cord Injury Rehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/tscir.kglmeridian.com\/view\/journals\/tscr\/30\/2\/article-p78.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/meridian.allenpress.com\/tscir\/article-pdf\/30\/2\/78\/3377054\/i1537-2073-30-2-78.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/tscir.kglmeridian.com\/downloadpdf\/journals\/tscr\/30\/2\/article-p78.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/tscir.kglmeridian.com\/downloadpdf\/journals\/tscr\/30\/2\/article-p78.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T15:51:03Z","timestamp":1775145063000},"score":1,"resource":{"primary":{"URL":"https:\/\/tscir.kglmeridian.com\/view\/journals\/tscr\/30\/2\/article-p78.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":158,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.46292\/sci23-00068","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.06.28.22276567","asserted-by":"object"}]},"ISSN":["1082-0744","1945-5763"],"issn-type":[{"value":"1082-0744","type":"print"},{"value":"1945-5763","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]}}}