{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:57:45Z","timestamp":1784944665220,"version":"3.55.0"},"reference-count":76,"publisher":"American Spinal Injury Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"\n Background:<\/jats:title>\n One in two individuals with spinal cord injury (SCI) experiences postprandial hypotension (PPH), a decline (>20 mm Hg) in systolic blood pressure (SBP) within 2 hours after eating. Consuming meals with a low glycemic index (GI) could prevent or lessen PPH.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n To determine the effect of a low-GI diet on PPH and postprandial glucose and insulin in individuals with chronic SCI (>1 year postinjury).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Eleven participants (6 males, 5 females; age 43 \u00b1 11 years) with chronic SCI (C4-C7, 7; T4-T12, 4) took part in a randomized crossover study (low GI vs. high GI). On each occasion, BP, glucose, and insulin were measured in the fasted state and for 2 hours after consuming a breakfast meal (60% carbohydrate, 28% fat, 12% protein) in laboratory-controlled conditions. Participants wore an ambulatory BP monitor and continuous glucose monitor for 3 days at home, and consumed study meals that were macronutrient-matched across conditions.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The maximum decrease in systolic blood pressure (SBP) following the laboratory-controlled breakfast meals tended to be lower in the low-GI (14 \u00b1 12 mm Hg) compared to the high-GI (24 \u00b1 25 mm Hg) diet (\n d<\/jats:italic>\n = 0.52,\n P<\/jats:italic>\n = .056). Serum glucose (\n P<\/jats:italic>\n < .01) and insulin (\n P<\/jats:italic>\n = .026) concentrations were lower at 30 minutes in the low-GI diet. In the home setting, peak glucose concentrations were lower after lunch (\n P<\/jats:italic>\n = .011) and dinner (\n P<\/jats:italic>\n < .01) in the low-GI diet.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n A low-GI meal may be an effective solution to reduce the magnitude of PPH and peak glucose concentrations in individuals with chronic SCI.<\/jats:p>\n <\/jats:sec>","DOI":"10.46292\/sci24-00044","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T11:39:57Z","timestamp":1740051597000},"page":"30-41","source":"Crossref","is-referenced-by-count":2,"title":["The Effect of a Low-Glycemic Index Diet on Postprandial Hypotension in Individuals With Chronic Spinal Cord Injury: Results From a Pilot Study"],"prefix":"10.46292","volume":"31","author":[{"given":"Matthew","family":"Farrow","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"Chahande","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"},{"name":"Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Minarsch","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonya","family":"Orchard","sequence":"additional","affiliation":[{"name":"Department of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Schwab","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"},{"name":"Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceren","family":"Yarar-Fisher","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio"},{"name":"Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"25425","reference":[{"issue":"11","key":"b1","series-title":"Lancet Neurol","first-page":"1026","article-title":"regional, and national burden of spinal cord injury, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019","volume":"22","author":"Global","year":"2023","unstructured":"Global\n , regional, and national burden of spinal cord injury, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019. 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