{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:51:29Z","timestamp":1775148689769,"version":"3.50.1"},"reference-count":0,"publisher":"American Spinal Injury Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Spasticity is a common complication following traumatic spinal cord injury (TSCI) that impacts neurofunctional recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to determine the prevalence of acute and late spasticity and identify clinical predictors associated with spasticity onset within the first year after TSCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective longitudinal cohort study involving 156 adults hospitalized for acute supraconal (C1-T12) TSCI at a level 1 trauma center from April 1, 2010, to December 31, 2021. Independent factors included demographic variables (age, sex, body mass index), trauma-related characteristics, and acute medical complications. Spasticity onset was categorized as acute (during acute hospitalization), late (after acute hospitalization within 1 year), or none. Multinomial logistic regression model was used to identify factors associated with the period of spasticity onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among the patients, 57 (36.5%) developed acute spasticity (mean onset at 24.7 \u00b1 13.7 days after admission), 55 (35.3%) experienced late spasticity, and 44 (28.2%) showed no spasticity within the first year. Higher AIS motor score at admission was associated with greater likelihood of either late or no spasticity (OR 1.05,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001; OR 1.02,\n                      <jats:italic>P<\/jats:italic>\n                      = .04). High-energy trauma increased the risk of developing acute spasticity (OR 0.37,\n                      <jats:italic>P<\/jats:italic>\n                      = .04). An AIS motor score below 50 (most severely impaired) at admission identified individuals at higher risk of acute spasticity, with 85.7% sensitivity and 71% overall accuracy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Greater injury severity and high-energy trauma are associated with early spasticity onset, highlighting the need for early risk stratification and personalized management strategies to optimize patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.46292\/sci25-00032","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T02:19:05Z","timestamp":1769998745000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of Acute and Late Spasticity After Traumatic Spinal Cord Injury: Implications for Recovery"],"prefix":"10.46292","author":[{"given":"Andr\u00e9ane","family":"Richard-Denis","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Centre de Recherche du CIUSSS du-Nord-de-l\u2019\u00cele-de-Montr\u00e9al, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montreal, Quebec, Canada"},{"name":"Centre de Recherche Interdisciplinaire en R\u00e9adaptation du Montr\u00e9al M\u00e9tropolitain (CRIR), Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert Kabeya","family":"Meji","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Centre de Recherche du CIUSSS du-Nord-de-l\u2019\u00cele-de-Montr\u00e9al, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoine","family":"Dionne","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Centre de Recherche du CIUSSS du-Nord-de-l\u2019\u00cele-de-Montr\u00e9al, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal Mputu","family":"Mputu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Centre de Recherche du CIUSSS du-Nord-de-l\u2019\u00cele-de-Montr\u00e9al, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marc","family":"Mac-Thiong","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada"},{"name":"Centre de Recherche du CIUSSS du-Nord-de-l\u2019\u00cele-de-Montr\u00e9al, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montreal, Quebec, Canada"},{"name":"Sainte-Justine University Hospital Research Center, Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"25425","container-title":["Topics in Spinal Cord Injury Rehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/tscir.kglmeridian.com\/view\/journals\/tscr\/aop\/article-10.46292-sci25-00032\/article-10.46292-sci25-00032.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/meridian.allenpress.com\/tscir\/article-pdf\/doi\/10.46292\/sci25-00032\/3549636\/10.46292_sci25-00032.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/tscir.kglmeridian.com\/downloadpdf\/journals\/tscr\/aop\/article-10.46292-sci25-00032\/article-10.46292-sci25-00032.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/tscir.kglmeridian.com\/downloadpdf\/journals\/tscr\/aop\/article-10.46292-sci25-00032\/article-10.46292-sci25-00032.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T15:50:56Z","timestamp":1775145056000},"score":1,"resource":{"primary":{"URL":"https:\/\/tscir.kglmeridian.com\/view\/journals\/tscr\/aop\/article-10.46292-sci25-00032\/article-10.46292-sci25-00032.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.46292\/sci25-00032","relation":{},"ISSN":["1082-0744","1945-5763"],"issn-type":[{"value":"1082-0744","type":"print"},{"value":"1945-5763","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,1]]}}}