{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T09:11:05Z","timestamp":1761210665974,"version":"build-2065373602"},"reference-count":9,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","license":[{"start":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T00:00:00Z","timestamp":1640908800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Rheumatology"],"abstract":"<jats:p>Adult-onset Still's disease (AOSD) is a rare multisystem autoinflammatory condition of unknown etiology, that may affect the heart, liver, reticuloendothelial system, and lungs.[1] Pleuritis and pleural effusion are the most common respiratory manifestations, occurring in 30 to 40% of cases.[2] The pleural features are usually mild and easily treated with non-steroidal anti-inflammatory drugs or glucocorticoid. However, there are severe cases requiring biological therapy.[3] Intriguingly, a description of a patient with AOSD requiring pleurodesis to stop pleural effusion flow has never been previously described in the literature.\r\nA 49-year-old female patient was admitted with recurrent episodes of fever (39.4\u00b0C), transient rash, weight loss, sore throats, and polyarthritis of wrists, knees, metacarpophalangeal and proximal interphalangeal joints in November 2012. No splenomegaly, hepatomegaly or lymphadenopathy was detected. Laboratory tests revealed a hemoglobin of 11.9 g\/dL (12-16 g\/dL), white blood cell count of 12,800 cells\/mm3 (4,000-10,000 cells\/mm3), platelets of 798,000\/\u03bcL (150,000-450,000\/\u03bcL), aspartate aminotransferase of 62 U\/L, alanine aminotransferase of 86 U\/L, C-reactive protein (CRP) of 44.1 mg\/dL (<\/jats:p>","DOI":"10.46497\/archrheumatol.2022.8630","type":"journal-article","created":{"date-parts":[[2021,8,6]],"date-time":"2021-08-06T06:14:29Z","timestamp":1628230469000},"page":"623-625","source":"Crossref","is-referenced-by-count":0,"title":["Still\u2019s disease with pleural effusion submitted to a pleurodesis"],"prefix":"10.5152","volume":"36","author":[{"family":"Joz\u00e9lio Carvalho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Aaron Lerner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2021,12,31]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"Feist E, Mitrovic S, Fautrel B. Mechanisms, biomarkers and targets for adult-onset Still's disease. Nat Rev Rheumatol 2018;14:603-18.","DOI":"10.1038\/s41584-018-0081-x"},{"key":"ref-2","doi-asserted-by":"crossref","unstructured":"Cheema GS, Quismorio FP Jr. Pulmonary involvement in adult-onset Still\u2019s disease. Curr Opin Pulm Med 1999;5:305-9.","DOI":"10.1097\/00063198-199909000-00007"},{"key":"ref-3","unstructured":"Quartuccio L, Salvin S, Zuliani F, Mansutti E, De Vita S. Pleuritis is a red flag for adult-onset Still's disease which may require biologic therapies. Clin Exp Rheumatol 2012;30:807."},{"key":"ref-4","unstructured":"Masson C, Le Loet X, Liote F, Dubost JJ, Boissier MC, Perroux-Goumy L, et al. Comparative study of 6 types of criteria in adult Still's disease. J Rheumatol 1996;23:495-7."},{"key":"ref-5","doi-asserted-by":"crossref","unstructured":"Senthilvel E, Papadakis A, McNamara M, Adebambo I. Adult-Onset Still Disease (AOSD). J Am Board Fam Med 2010;23:418-22.","DOI":"10.3122\/jabfm.2010.03.090157"},{"key":"ref-6","doi-asserted-by":"crossref","unstructured":"Uppal SS, Al-Mutairi M, Hayat S, Abraham M, Malaviya A. Ten years of clinical experience with adult onset Still's disease: Is the outcome improving? Clin Rheumatol 2007;26:1055-60.","DOI":"10.1007\/s10067-006-0440-x"},{"key":"ref-7","doi-asserted-by":"crossref","unstructured":"Kawaguchi H, Tsuboi H, Yagishita M, Terasaki T, Terasaki M, Shimizu M, et al. Severe adult-onset still disease with constrictive pericarditis and pleuritis that was successfully treated with tocilizumab in addition to corticosteroids and Cyclosporin A. Intern Med 2018;57:1033-8.","DOI":"10.2169\/internalmedicine.9809-17"},{"key":"ref-8","unstructured":"Efthimiou P, Flavell RA, Furlan A, Gasbarrini G, Gava A, Kon\u00e9-Paut I, et al. Autoinflammatory syndromes and infections: Pathogenetic and clinical implications. Clin Exp Rheumatol 2008;26(1 Suppl 48):S53-61."},{"key":"ref-9","doi-asserted-by":"crossref","unstructured":"Zeng T, Zou YQ, Wu MF, Yang CD. Clinical features and prognosis of adult-onset still's disease: 61 cases from China. J Rheumatol 2009;36:1026-31.","DOI":"10.3899\/jrheum.080365"}],"container-title":["Archives of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1228\/2149","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1228\/2150","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/1228\/2149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T09:05:37Z","timestamp":1761210337000},"score":1,"resource":{"primary":{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/view\/1228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":9,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12,31]]}},"URL":"https:\/\/doi.org\/10.46497\/archrheumatol.2022.8630","relation":{},"ISSN":["2618-6500"],"issn-type":[{"type":"electronic","value":"2618-6500"}],"subject":[],"published":{"date-parts":[[2021,12,31]]}}}