{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T09:06:15Z","timestamp":1761210375007,"version":"build-2065373602"},"reference-count":39,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"4","license":[{"start":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T00:00:00Z","timestamp":1703980800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Rheumatology"],"abstract":"<jats:p>Objectives: This study focused on the symptomatic and the functional evaluation in correlations to median nerve elasticity, its ultrasound parameters, and the electrodiagnostic grading of primary carpal tunnel syndrome (CTS) patients.\r\nPatients and methods: In the case-control study, 100 wrists of 57 CTS patients (54 females, 3 males; mean age: 39\u00b19.8 years; range, 20 to 60 years) clinically diagnosed according to the American Academy of Neurology Clinical Diagnostic Criteria were evaluated between December 2019 and December 2020. The control group included 110 nondiseased wrists of 55 sex- and age-matched healthy subjects (males 7, females 48; mean age: 35.7\u00b110.3 years; range 20 to 58 years). Functional assessment using Hi-Ob-Db clinical scale, electrodiagnosis, ultrasonographic screening, and elasticity evaluation were done for all patients.\r\nResults: CTS patients had an increased stiffness of the median nerve compared to controls. Functional stages were positively correlated with the ultrasonographic parameters and the electrodiagnostic stages of CTS. The elastogram of clinically diagnosed patients was revealed more stiffness of the MN, with negative electrodiagnosis results.\r\nConclusion: Clinically diagnosed CTS could be missed by the electrodiagnosis but then properly figured by ultrasonography and potentially graded by sonoelastography. Sonoelastography may be an effective method for early diagnosis and appropriate grading of CTS.<\/jats:p>","DOI":"10.46497\/archrheumatol.2023.10022","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T06:11:37Z","timestamp":1701756697000},"page":"620-632","source":"Crossref","is-referenced-by-count":1,"title":["Elastosonography and electrodiagnosis in relation to symptomatic and functional grading of carpal tunnel syndrome"],"prefix":"10.5152","volume":"38","author":[{"family":"Marwa Yahia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ahmed El Shambaky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Doaa Lasheen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2023,12,31]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"Atroshi I, Gummesson C, Johnsson R, Ornstein E, Ranstam J, Ros\u00e9n I. Prevalence of carpal tunnel syndrome in a general population. JAMA 1999;282:153-8. doi: 10.1001\/jama.282.2.153.","DOI":"10.1001\/jama.282.2.153"},{"key":"ref-2","doi-asserted-by":"crossref","unstructured":"de Krom MC, Knipschild PG, Kester AD, Thijs CT, Boekkooi PF, Spaans F. Carpal tunnel syndrome: Prevalence in the general population. J Clin Epidemiol 1992;45:373-6. doi: 10.1016\/0895- 4356(92)90038-o.","DOI":"10.1016\/0895-4356(92)90038-O"},{"key":"ref-3","doi-asserted-by":"crossref","unstructured":"Nam K, Peterson SM, Wessner CE, Machado P, Forsberg F. Diagnosis of carpal tunnel syndrome using shear wave elastography and high-frequency ultrasound imaging. Acad Radiol 2021;28:e278-87. doi: 10.1016\/j.acra.2020.08.011.","DOI":"10.1016\/j.acra.2020.08.011"},{"key":"ref-4","doi-asserted-by":"crossref","unstructured":"Snoj \u017d, Wu CH, Taljanovic MS, Dumi\u0107-\u010cule I, Drakonaki EE, Klauser AS. Ultrasound elastography in musculoskeletal radiology: Past, present, and future. Semin Musculoskelet Radiol 2020;24:156-66. doi: 10.1055\/s-0039-3402746.","DOI":"10.1055\/s-0039-3402746"},{"key":"ref-5","doi-asserted-by":"crossref","unstructured":"Miyamoto H, Morizaki Y, Kashiyama T, Tanaka S. Grey-scale sonography and sonoelastography for  diagnosing carpal tunnel syndrome. World J Radiol 2016;8:281-7. doi: 10.4329\/wjr.v8.i3.281.","DOI":"10.4329\/wjr.v8.i3.281"},{"key":"ref-6","doi-asserted-by":"crossref","unstructured":"Taljanovic MS, Gimber LH, Becker GW, Latt LD, Klauser AS, Melville DM, et al. Shear-wave elastography: Basic physics and musculoskeletal applications. Radiographics 2017;37:855-70. doi: 10.1148\/rg.2017160116.","DOI":"10.1148\/rg.2017160116"},{"key":"ref-7","doi-asserted-by":"crossref","unstructured":"Elsayed M, Saber Mohamed MA, Afifi LM, Wafaie AM. The role of sonoelastography in diagnosis and grading of patients with carpal tunnel syndrome. Med J Cairo Univ 2021;89:2203-11. doi: 10.21608\/ mjcu.2021.203691.","DOI":"10.21608\/mjcu.2021.203691"},{"key":"ref-8","unstructured":"Ogur T, Yakut ZI, Teber MA, Alp F, Turan A, Tural A, et al. Ultrasound elastographic evaluation of the median nerve in pregnant women with carpal tunnel syndrome. Eur Rev Med Pharmacol Sci 2015;19:23-30."},{"key":"ref-9","doi-asserted-by":"crossref","unstructured":"Nam K, Peterson SM, Wessner CE, Machado P, Forsberg F. Diagnostic performance of shear wave elastography for carpal tunnel syndrome combined with high frequency ultrasound imaging. 2020 IEEE International Ultrasonics Symposium (IUS), Las Vegas, NV, USA, 2020. p. 1-4, doi: 10.1109\/ IUS46767.2020.9251485.","DOI":"10.1109\/IUS46767.2020.9251485"},{"key":"ref-10","doi-asserted-by":"crossref","unstructured":"Mohammadi A, Afshar A, Mirza-Aghazadeh-Attari M, Mokhtari SAS. Application of shear wave elastography and median nerve cross-section area in the diagnosis and staging of carpal tunnel syndrome: A case-control study. Pol J Radiol 2021;86:e638-43. doi: 10.5114\/ pjr.2021.111437.","DOI":"10.5114\/pjr.2021.111437"},{"key":"ref-11","doi-asserted-by":"crossref","unstructured":"Lasheen DR, Abdelmoneam SM, El Shambaky AY, Mahgoub MY. Sonoelastography of the median nerve in carpal tunnel syndrome in correlation with nerve conduction studies. BJAS 2021;6:357-63.","DOI":"10.21608\/bjas.2021.214839"},{"key":"ref-12","doi-asserted-by":"crossref","unstructured":"Caliandro P, Giannini F, Pazzaglia C, Aprile I, Minciotti I, Granata G, et al. A new clinical scale to grade the impairment of median nerve in carpal tunnel syndrome. Clin Neurophysiol 2010;121:1066- 71. doi: 10.1016\/j.clinph.2010.02.002.","DOI":"10.1016\/j.clinph.2010.02.002"},{"key":"ref-13","doi-asserted-by":"crossref","unstructured":"American Association of Electrodiagnostic Medicine, American Academy of Neurology, and American Academy of Physical Medicine and Rehabilitation. Practice parameter for electrodiagnostic studies in carpal tunnel syndrome: Summary statement. Muscle Nerve 2002;25:918-22. doi: 10.1002\/ mus.10185.","DOI":"10.1002\/mus.10185"},{"key":"ref-14","doi-asserted-by":"crossref","unstructured":"Bland JD. A neurophysiological grading scale for carpal tunnel syndrome. Muscle Nerve 2000;23:1280- 3. doi: 10.1002\/1097-4598(200008)23:83.0.co;2-y.","DOI":"10.1002\/1097-4598(200008)23:8<1280::AID-MUS20>3.0.CO;2-Y"},{"key":"ref-15","doi-asserted-by":"crossref","unstructured":"Tatar IG, Kurt A, Yavasoglu NG, Hekimoglu B. Carpal tunnel syndrome: Elastosonographic strain ratio and cross-sectional area evaluation for the diagnosis and disease severity. Med Ultrason 2016;18:305-11. doi: 10.11152\/mu.2013.2066.183.tat.","DOI":"10.11152\/mu.2013.2066.183.tat"},{"key":"ref-16","doi-asserted-by":"crossref","unstructured":"Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39:175-91. doi: 10.3758\/ bf03193146.","DOI":"10.3758\/BF03193146"},{"key":"ref-17","doi-asserted-by":"crossref","unstructured":"Ibrahim HR. Diagnostic value of median nerve shear wave ultrasound elastography in diagnosis and differentiation of carpal tunnel syndrome severity. Egypt J Radiol Nucl Med 2021;52:187. doi: 10.1186\/ s43055-021-00573-3.","DOI":"10.1186\/s43055-021-00573-3"},{"key":"ref-18","doi-asserted-by":"crossref","unstructured":"Genova A, Dix O, Saefan A, Thakur M, Hassan A. Carpal tunnel syndrome: A review of literature. Cureus 2020;12:e7333. doi: 10.7759\/cureus.7333.","DOI":"10.7759\/cureus.7333"},{"key":"ref-19","doi-asserted-by":"crossref","unstructured":"Ciloglu O, G\u00f6rg\u00fcl\u00fc FF. Which ultrasound parameter is more accurate in the diagnosis of carpal tunnel syndrome: Cross-sectional area, resistive index, or strain ratio? Am J Phys Med Rehabil 2020;99:842-6. doi: 10.1097\/PHM.0000000000001464.","DOI":"10.1097\/PHM.0000000000001464"},{"key":"ref-20","doi-asserted-by":"crossref","unstructured":"Lin CP, Chen IJ, Chang KV, Wu WT, \u00d6z\u00e7akar L. Utility of ultrasound elastography in evaluation of carpal tunnel syndrome: A systematic review and meta-analysis. Ultrasound Med Biol 2019;45:2855- 65. doi: 10.1016\/j.ultrasmedbio.2019.07.409.","DOI":"10.1016\/j.ultrasmedbio.2019.07.409"},{"key":"ref-21","doi-asserted-by":"crossref","unstructured":"van Holsbeeck M, Soliman S, Van Kerkhove F, Craig J. Advanced musculoskeletal ultrasound techniques: What are the applications? AJR Am J Roentgenol 2021;216:436-45. doi: 10.2214\/AJR.20.22840.","DOI":"10.2214\/AJR.20.22840"},{"key":"ref-22","doi-asserted-by":"crossref","unstructured":"Sartorio F, Dal Negro F, Bravini E, Ferriero G, Corna S, Invernizzi M, et al. Relationship between nerve conduction studies and the Functional Dexterity Test in workers with carpal tunnel syndrome. BMC Musculoskelet Disord 2020;21:679. doi: 10.1186\/ s12891-020-03651-1.","DOI":"10.1186\/s12891-020-03651-1"},{"key":"ref-23","doi-asserted-by":"crossref","unstructured":"Karatay E, T\u00fcrko\u00a4lu \u00d6, Mans\u0131z Kaplan B. Assessment of diagnostic efficiency of real-time strain elastography by using the median nerve stiffness at females with carpal tunnel syndrome. Cukurova Med J 2020;45:1276-82. doi: 10.17826\/cumj.745698.","DOI":"10.17826\/cumj.745698"},{"key":"ref-24","doi-asserted-by":"crossref","unstructured":"Martin MJ, Cartwright MS. A pilot study of strain elastography in the diagnosis of carpal tunnel syndrome. J Clin Neurophysiol 2017;34:114-8. doi: 10.1097\/WNP.0000000000000334.","DOI":"10.1097\/WNP.0000000000000334"},{"key":"ref-25","doi-asserted-by":"crossref","unstructured":"Cingoz M, Kandemirli SG, Alis DC, Samanci C, Kandemirli GC, Adatepe NU. Evaluation of median nerve by shear wave elastography and diffusion tensor imaging in carpal tunnel syndrome. Eur J Radiol 2018;101:59-64. doi: 10.1016\/j. ejrad.2018.02.005.","DOI":"10.1016\/j.ejrad.2018.02.005"},{"key":"ref-26","doi-asserted-by":"crossref","unstructured":"Orman G, Ozben S, Huseyinoglu N, Duymus M, Orman KG. Ultrasound elastographic evaluation in the diagnosis of carpal tunnel syndrome: Initial findings. Ultrasound Med Biol 2013;39:1184-9. doi: 10.1016\/j.ultrasmedbio.2013.02.016.","DOI":"10.1016\/j.ultrasmedbio.2013.02.016"},{"key":"ref-27","doi-asserted-by":"crossref","unstructured":"Atroshi I, Gummesson C, Johnsson R, Ornstein E. Diagnostic properties of nerve conduction tests in population-based carpal tunnel syndrome. BMC Musculoskelet Disord 2003;4:9. doi: 10.1186\/1471- 2474-4-9.","DOI":"10.1186\/1471-2474-4-9"},{"key":"ref-28","doi-asserted-by":"crossref","unstructured":"Witt JC, Hentz JG, Stevens JC. Carpal tunnel syndrome with normal nerve conduction studies. Muscle Nerve 2004;29:515-22. doi: 10.1002\/mus.20019.","DOI":"10.1002\/mus.20019"},{"key":"ref-29","doi-asserted-by":"crossref","unstructured":"Emara DM, El Shafei MM, Abdel Naby HM. Utility of ultrasound elastography in a cohort of patients with idiopathic carpal tunnel syndrome. EJRNM 2018;49:408-14.","DOI":"10.1016\/j.ejrnm.2018.02.001"},{"key":"ref-30","doi-asserted-by":"crossref","unstructured":"Park EJ, Hahn S, Yi J, Shin KJ, Lee Y, Lee HJ. Comparison of the diagnostic performance of strain elastography and shear wave elastography for the diagnosis of carpal tunnel syndrome. J Ultrasound Med 2021;40:1011-21. doi: 10.1002\/jum.15478.","DOI":"10.1002\/jum.15478"},{"key":"ref-31","doi-asserted-by":"crossref","unstructured":"Miyamoto H, Halpern EJ, Kastlunger M, Gabl M, Arora R, Bellmann-Weiler R, et al. Carpal tunnel syndrome: Diagnosis by means of median nerve elasticity--improved diagnostic accuracy of US with sonoelastography. Radiology 2014;270:481-6. doi: 10.1148\/radiol.13122901.","DOI":"10.1148\/radiol.13122901"},{"key":"ref-32","doi-asserted-by":"crossref","unstructured":"Asadov R, Erdal A, Bu\u00a4dayc\u0131 O, G\u00fcnd\u00fcz OH, Ekinci G. The effectiveness of ultrasonography and ultrasonographic elastography in the diagnosis of carpal tunnel syndrome and evaluation of treatment response after steroid injection. Eur J Radiol 2018;108:172-6. doi: 10.1016\/j.ejrad.2018.09.027.","DOI":"10.1016\/j.ejrad.2018.09.027"},{"key":"ref-33","doi-asserted-by":"crossref","unstructured":"Tezcan S, Ulu Ozturk F, Uslu N, Nalbant M, Umit Yemisci O. Carpal tunnel syndrome: Evaluation of the effects of low-level laser therapy with ultrasound strain imaging. J Ultrasound Med 2019;38:113-22. doi: 10.1002\/jum.14669.","DOI":"10.1002\/jum.14669"},{"key":"ref-34","doi-asserted-by":"crossref","unstructured":"Yoshii Y, Tung WL, Yuine H, Ishii T. Postoperative diagnostic potentials of median nerve strain and applied pressure measurement after carpal tunnel release. BMC Musculoskelet Disord 2020;21:22. doi: 10.1186\/s12891-019-3033-y.","DOI":"10.1186\/s12891-019-3033-y"},{"key":"ref-35","doi-asserted-by":"crossref","unstructured":"Jablecki CK, Andary MT, So YT, Wilkins DE, Williams FH. Literature review of the usefulness of nerve conduction studies and electromyography for the evaluation of patients with carpal tunnel syndrome. AAEM Quality Assurance Committee. Muscle Nerve 1993;16:1392-414. doi: 10.1002\/ mus.880161220.","DOI":"10.1002\/mus.880161220"},{"key":"ref-36","doi-asserted-by":"crossref","unstructured":"Aseem F, Williams JW, Walker FO, Cartwright MS. Neuromuscular ultrasound in patients with carpal tunnel syndrome and normal nerve conduction studies. Muscle Nerve 2017;55:913-5. doi: 10.1002\/mus.25462.","DOI":"10.1002\/mus.25462"},{"key":"ref-37","doi-asserted-by":"crossref","unstructured":"Moran L, Perez M, Esteban A, Bellon J, Arranz B, del Cerro M. Sonographic measurement of crosssectional area of the median nerve in the diagnosis of carpal tunnel syndrome: Correlation with nerve conduction studies. J Clin Ultrasound 2009;37:125- 31. doi: 10.1002\/jcu.20551.","DOI":"10.1002\/jcu.20551"},{"key":"ref-38","doi-asserted-by":"crossref","unstructured":"Ratasvuori M, Sormaala M, Kinnunen A, Lindfors N. Ultrasonography for the diagnosis of carpal tunnel syndrome: Correlation of clinical symptoms, cross-sectional areas and electroneuromyography. J Hand Surg Eur Vol 2022;47:369-74. doi: 10.1177\/17531934211059808.","DOI":"10.1177\/17531934211059808"},{"key":"ref-39","doi-asserted-by":"crossref","unstructured":"Moran L, Royuela A, de Vargas AP, Lopez A, Cepeda Y, Martinelli G. Carpal tunnel syndrome: Diagnostic usefulness of ultrasound measurement of the median nerve area and quantitative elastographic measurement of the median nerve stiffness. 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