{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:49:21Z","timestamp":1791679761482,"version":"4.3.4"},"reference-count":17,"publisher":"SAABRON PRESS","issue":"2","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:sec id=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multiple myeloma (MM) is an incurable hematological malignancy with increasing prevalence. While randomized controlled trials have demonstrated survival improvements, they underrepresent older and comorbid patients. Real-world data from observational cohorts are therefore essential.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the comparability of patient, hospitalization and center characteristics for patients treated in centers included in the French Epidemiology of Multiple MYeloma (EmmY) cohort with those treated in centers of the French-speaking Intergroupe Francophone du My\u00e9lome (IFM) network (including EmmY) and those treated in all centers treating MM in France between 2017\u20132023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed French national hospital discharge data (PMSI) to identify adults hospitalized with MM (ICD-10 C90) between August 2017 and December 2023. Patient demographics, comorbidities, hospitalization characteristics, and center profiles were compared between the three cohorts using standardized differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 69,276 patients (including 50,243 IFM and 33,785 EmmY), 1,871,369 hospitalizations (including 1,484,288 IFM and 1,022,462 EmmY), and 323 centers (including 118 IFM and 70 EmmY). EmmY centers were larger and treated a higher mean proportion of MM patients (2.7%) per center than IFM (2.4%) and all MM centers (1.3%). No clinically meaningful differences were observed between EmmY and IFM centers regarding patient age, sex, comorbidities, treatment patterns, or hospitalization outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The EmmY cohort is highly comparable to patients treated in specialized MM centers and those within the broader French MM population, supporting its validity as a robust real-world data source. It is well-suited for evaluating treatment pathways and outcomes in real-world MM populations, including patients underrepresented in randomized controlled trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.46989\/001c.161361","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T22:03:25Z","timestamp":1779833005000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparison of patient, hospitalization and center characteristics from the EMMY centers, IFM centers, and all multiple myeloma centers in France"],"prefix":"10.46989","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2361-9669","authenticated-orcid":false,"given":"Decaux","family":"Olivier","sequence":"first","affiliation":[{"name":"Service d\u2019h\u00e9matologie clinique, CHU de Rennes, Rennes, France"},{"name":"MOBIDIC - Microenvironment and B-cells: Immunopathology, Cell Differentiation, and Cancer, CHU Rennes, Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronan","family":"GARLANTEZEC","sequence":"additional","affiliation":[{"name":"Sant\u00e9 publique et \u00e9pid\u00e9miologie, CHU de Rennes, Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurore","family":"PERROT","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/014hxhm89","id-type":"ROR","asserted-by":"publisher"}],"name":"Service d'h\u00e9matologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulous, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"MACRO","sequence":"additional","affiliation":[{"name":"Service d'h\u00e9matologie, CHU Caen, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"ROYER","sequence":"additional","affiliation":[{"name":"Service d'Immuno-h\u00e9matologie, H\u00f4pital Saint Louis, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"BELHADJ MERZOUG","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04m61mj84","id-type":"ROR","asserted-by":"publisher"}],"name":"Unit\u00e9 Fonctionnelle H\u00e9mopathies Lympho\u00efdes CHU. Henri Mondor, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"VINCENT","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mthsf17","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Clinical Hematology, Montpellier University Hospital Center, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"CHALOPIN","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00jpq0w62","id-type":"ROR","asserted-by":"publisher"}],"name":"Service d'h\u00e9matologie et Th\u00e9rapie Cellulaire, Centre Hospitalier Universitaire (CHU) Tours, H\u00f4pital Bretonneau, Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"FRENZEL","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05tr67282","id-type":"ROR","asserted-by":"publisher"}],"name":"Service d'h\u00e9matologie adulte - Responsable centre r\u00e9gional de traitement de l'h\u00e9mophilie CRTH - Centre national de r\u00e9f\u00e9rence des mastocytoses CEREMAST, H\u00f4pital Necker-Enfant Malade, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"BOBIN","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/029s6hd13","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Hematology, University of Poitiers, Poitiers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"MOHTY","sequence":"additional","affiliation":[{"name":"Department of Haematology, Saint Antoine Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrille","family":"TOUZEAU","sequence":"additional","affiliation":[{"name":"Hematology Department, University Hospital H\u00f4tel-Dieu, Nantes, 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Gil","year":"2022","journal-title":"Clinical Hematology International"},{"issue":"4","key":"ref12","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1002\/jha2.802","article-title":"Real-world experience of novel multiple myeloma treatments in a large, single-center cohort in Finland","volume":"4","author":"H. Loponen","year":"2023","journal-title":"eJHaem"},{"issue":"4","key":"ref13","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1213\/ANE.0000000000002920","article-title":"Propensity Score Methods: Theory and Practice for Anesthesia Research","volume":"127","author":"P. J. Schulte","year":"2018","journal-title":"Anesthesia and Analgesia"},{"issue":"11","key":"ref14","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.2217\/fon-2020-0946","article-title":"Health-related quality of life and utility outcomes with selinexor in relapsed\/refractory diffuse large B-cell lymphoma","volume":"17","author":"J. Shah","year":"2021","journal-title":"Future Oncology (London, England)"},{"issue":"2","key":"ref15","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1038\/s41408-021-00432-4","article-title":"Management of patients with multiple myeloma beyond the clinical-trial setting: Understanding the balance between efficacy, safety and tolerability, and quality of life","volume":"11","author":"E. Terpos","year":"2021","journal-title":"Blood Cancer Journal"},{"issue":"5","key":"ref16","doi-asserted-by":"publisher","first-page":"e0322474","DOI":"10.1371\/journal.pone.0322474","article-title":"Epidemiology of patients treated for multiple myeloma using a new algorithm in the French national health insurance database (SNDS): Results from the MYLORD study","volume":"20","author":"C. Touzeau","year":"2025","journal-title":"PloS One"},{"issue":"6","key":"ref17","doi-asserted-by":"publisher","first-page":"e70619","DOI":"10.1002\/cam4.70619","article-title":"Real-World Outcomes of Newly Diagnosed Multiple Myeloma Patients Treated Before the Era of Anti-CD38 Antibodies: The EMMY Cohort From 2017 to 2020","volume":"14","author":"L. Vincent","year":"2025","journal-title":"Cancer Medicine"}],"container-title":["Clinical Hematology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chi.scholasticahq.com\/article\/161361-comparison-of-patient-hospitalization-and-center-characteristics-from-the-emmy-centers-ifm-centers-and-all-multiple-myeloma-centers-in-france","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:37:52Z","timestamp":1791679072000},"score":1,"resource":{"primary":{"URL":"https:\/\/chi.scholasticahq.com\/article\/161361-comparison-of-patient-hospitalization-and-center-characteristics-from-the-emmy-centers-ifm-centers-and-all-multiple-myeloma-centers-in-france"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":17,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.46989\/001c.161361","relation":{},"ISSN":["2590-0048"],"issn-type":[{"value":"2590-0048","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]}}}