{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:05:30Z","timestamp":1785420330036,"version":"3.56.0"},"reference-count":16,"publisher":"SAABRON PRESS","issue":"1","license":[{"start":{"date-parts":[[2024,3,3]],"date-time":"2024-03-03T00:00:00Z","timestamp":1709424000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>A lack of factor VIII (FVIII) or factor IX (FIX) results in hemophilia, a blood-clotting illness. The mode of inheritance is chromosome X-linked and recessive. The primary symptom of severe hemophilia is spontaneous and recurrent bleeding into joints, muscles, and soft tissues. Unpreventable bleeding may cause arthropathy, chronic discomfort, and muscular atrophy. Therefore, joints\u2019 functional loss affects the functional and walking ability. The aim of this study was to determine the walking ability by measuring the 50-m walk test time in severe hemophilic patients, as compared to the normal population. Sixty subjects (males) in the 18-30 year age group were selected and comprised 30 hemophiliacs and 30 in a control group. The 50-m walking ability was measured in seconds. The results showed a normative value of 36.6 sec in the control and 67.2 sec in the hemophilic group. Statistical analysis of the data showed that the walking ability was significantly reduced in the hemophilic group. These normative values illustrate a useful, simple, reproducible, rapid assessment of walking disability in adults with hemophilic arthropathy, and also aid the planning of treatment.<\/jats:p>","DOI":"10.46989\/001c.94374","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T23:58:02Z","timestamp":1709423882000},"source":"Crossref","is-referenced-by-count":3,"title":["Walking ability in adults with severe hemophilia: A cross-sectional study"],"prefix":"10.46989","volume":"6","author":[{"given":"Malika","family":"Jhandai","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xpvwe80","id-type":"ROR","asserted-by":"publisher"}],"name":"Pandit Bhagwat Dayal Sharma University of Health Sciences","department":["College of Physiotherapy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1337-9940","authenticated-orcid":false,"given":"Dimple","family":"Choudhry","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xpvwe80","id-type":"ROR","asserted-by":"publisher"}],"name":"Pandit Bhagwat Dayal Sharma University of Health Sciences","department":["College of Physiotherapy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5863-2392","authenticated-orcid":false,"given":"Sudhir Kumar","family":"Atri","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xpvwe80","id-type":"ROR","asserted-by":"publisher"}],"name":"Pandit Bhagwat Dayal Sharma University of Health Sciences","department":["Medicine Department"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0910-4303","authenticated-orcid":false,"given":"Pankaj","family":"Bhardwaj","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03xpvwe80","id-type":"ROR","asserted-by":"publisher"}],"name":"Pandit Bhagwat Dayal Sharma University of Health Sciences","department":["College of Physiotherapy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6368-804X","authenticated-orcid":false,"given":"Kusum","family":"Yadav","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0582p8j71","id-type":"ROR","asserted-by":"publisher"}],"name":"Jagannath University","department":["Department of Physiotherapy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"26435","published-online":{"date-parts":[[2024,3,3]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"publisher","first-page":"307","DOI":"10.3233\/bmr-130448","article-title":"Evaluation of joint findings with gait analysis in children with hemophilia","volume":"27","author":"Atilla Cayir","year":"2014","journal-title":"Journal of Back and Musculoskeletal Rehabilitation","ISSN":"https:\/\/id.crossref.org\/issn\/1878-6324","issn-type":"print"},{"issue":"3","key":"ref2","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1002\/pbc.22291","article-title":"Functional independence score in hemophilia: A cross-sectional study assessment of Mexican children","volume":"54","author":"Alberto Tlacuilo-Parra","year":"2010","journal-title":"Pediatric Blood & Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1545-5009","issn-type":"print"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"209","DOI":"10.2147\/jbm.s304597","article-title":"Asymptomatic joint bleeding and joint health in hemophilia: a review of variables, methods, and biomarkers","volume":"12","author":"Richard Gooding","year":"2021","journal-title":"Journal of Blood Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1179-2736","issn-type":"print"},{"issue":"6","key":"ref4","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/j.jpeds.2007.12.016","article-title":"Aerobic capacity in children with hemophilia","volume":"152","author":"Raoul H Engelbert","year":"2008","journal-title":"The Journal of Pediatrics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3476","issn-type":"print"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1002\/9781118398258.ch64","article-title":"Quality of life in hemophilia","author":"Sylvia von Mackensen","year":"2014","journal-title":"Textbook of hemophilia"},{"issue":"8","key":"ref6","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1093\/jpepsy\/25.8.545","article-title":"HIV-associated changes in adaptive, emotional, and behavioral functioning in children and adolescents with hemophilia: Results from the Hemophilia Growth and Development Study","volume":"25","author":"S. 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