{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:14:34Z","timestamp":1789578874696,"version":"build-2803163510"},"reference-count":35,"publisher":"Societatea Romana de Morfologie","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rom J Morphol Embryol"],"published-print":{"date-parts":[[2025,8,27]]},"abstract":"<jats:p>Background: External root resorption (ERR) represents a pathological condition of uncertain etiology and variable clinical presentation that can jeopardize the long-term prognosis of affected teeth. Aim: This study aimed to correlate radiological (cone-beam computed tomography \u2013 CBCT) and histological findings in three teeth affected by ERR with different localization (apical, middle or cervical), with a focus on the structural changes of the dental hard and soft tissues. Materials and Methods: Two monoradicular and one pluriradicular teeth diagnosed with ERR and external cervical resorption (ECR) based on initial periapical radiography were analyzed using CBCT and lesions were measured in all three planes and described after Patel\u2019s classification; after extraction\/root amputation, samples were decalcified and processed using standard histological techniques (Hematoxylin\u2013Eosin, van Gieson, Masson\u2019s trichrome). Results: Several key features were noticed at the site of resorptive areas: osteoclasts, large multinucleated cells responsible for the resorption of mineralized tissues positioned along the root surface, resulting in the formation of resorption lacunae. Adjacent to the resorptive areas, granulation tissue, with a dense network of capillaries and inflammatory cells, including fibroblasts. Extensive destruction of dentin, cementum, and enamel, presence of fibrous repair, osteoid formation, and dystrophic calcifications were noticed. Conclusions: The combined radiological\u2013histological evaluation enhances diagnostic accuracy and may guide therapeutic strategies.<\/jats:p>","DOI":"10.47162\/rjme.66.2.13","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T12:31:18Z","timestamp":1756729878000},"page":"391-398","source":"Crossref","is-referenced-by-count":4,"title":["External root resorptions: cone-beam computed tomography assessment and histopathological characterization"],"prefix":"10.47162","volume":"66","author":[{"name":"Discipline of Restorative Dentistry and Endodontics, Digital and Advanced Technique for Endodontic, \nRestorative and Prosthetic Treatment (TADERP) Research Center, Faculty of Dental Medicine, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Ro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana-Maria","family":"Talpo\u015f-Niculescu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lumini\u0163a Maria","family":"Nica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Restorative and Prosthetic Treatment (TADERP) Research Center, Faculty of Dental Medicine, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Cristina","family":"Rusu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Discipline of Oral Pathology, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, Faculty of Dental Medicine, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca Maria","family":"Clo\u015fca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pathology, Emergency City Hospital, Timi\u015foara, Romania; Department of Microscopic Morphology, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Zar\u0103","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pathology, Emergency City Hospital, Timi\u015foara, Romania; Department of Microscopic Morphology, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103lina","family":"Popa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Discipline of Pedodontics, Pediatric Dentistry Research Center, Faculty of Dental Medicine, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eerban","family":"Talpo\u015f-Niculescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Discipline of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, Victor Babe\u015f University of Medicine and Pharmacy, Timi\u015foara, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"26736","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"\"[1] Patel S, Krastl G, Weiger R, Lambrechts P, Tj\u00e4derhane L, Gambarini G, Teng PH. 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External cervical resorption: an analysis using cone beam and microfocus computed tomography and scanning electron microscopy. Int Endod J, 2013, 46(9):877-887. https:\/\/doi.org\/10.1111\/iej.12073","DOI":"10.1111\/iej.12073"},{"key":"ref33","doi-asserted-by":"publisher","unstructured":"[34] European Society of Endodontology; Patel S, Durack C, Abella F, Roig M, Shemesh H, Lambrechts P, Lemberg K. European Society of Endodontology Position Statement: the use of CBCT in endodontics. Int Endod J, 2014, 47(6):502-504. https:\/\/doi.org\/10.1111\/iej.12267","DOI":"10.1111\/iej.12267"},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"[35] Special Committee to Revise the Joint AAE\/AAOMR Position Statement on use of CBCT in Endodontics. AAE and AAOMR Joint Position Statement: use of cone beam computed tomography in endodontics 2015 update. 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