{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,12]],"date-time":"2024-10-12T04:08:56Z","timestamp":1728706136834},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"10 (Supple-08)","license":[{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Objective: To compare the effect of two ovulation induction drugs on anti-Mullerian hormone level in polycystic women.\r\nMethod: The experimental cohort study was done at the infertility outpatient clinics of Al-Yarmouk Teaching Hospital, Baghdad, Iraq, from May 2020 to April 2021, and comprised infertile women aged 18-35 years with confirmed diagnosis of polycystic ovarian syndrome. Baseline blood level of anti-Mullerian hormone was tested in all patients. The patients were divided into two groups. Group A patients received clomid 50mg twice daily to a maximum of 200mg for 5 days starting from the third day of the menstrual cycle. Group B patients received letrozole 2.5mg twice daily for 5 days starting from the third day of the menstrual cycle. After ovulation induction on day 12-14, a second sample of serum anti-Mullerian hormone was tested, and intergroup comparisons were done. Data were analysed by using the available statistical package of SPSS-28 (Statistical Packages for Social Sciences- version 28). Students-t-test , \u00a0Paired-t-test , Pearson correlation , t-test or ANOVA test Statistical significance was considered for P value equal or less than 0.05.\r\nResults: Of the 83 women, 41(49.4%) were in Group A with mean age 26.0\u00b14.9 years, while Group B had 42(50.6%) subjects with mean age 27.0\u00b15.1 years. Post-intervention, the level of anti-Mullerian hormone decreased significantly in both groups (p&lt;0.05). The decrease in Group B was more than Group A, but the difference was not significant (p&gt;0.05).\r\nConclusions: Ovulation induction drugs clomid and leterzole decreased the level of anti-Mullerian hormone significantly.\r\nKey Words: Polycystic Ovary, Anti-Mullerian Hormone, Letrozole, Infertility, Ovulation Induction, Ambulatory Care, Menstrual Cycle, Clomiphene<\/jats:p>","DOI":"10.47391\/jpma-bagh-16-21","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T14:23:08Z","timestamp":1728397388000},"page":"S91-S94","source":"Crossref","is-referenced-by-count":0,"title":["Comparison between the levels of anti mullerian hormone after treatment with clomid versus letrozole in polycystic women: an experimental study"],"prefix":"10.47391","volume":"74","author":[{"family":"Manal Madany Abdel Qader","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Shatha Sami Hussein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Huda Fadhil Jadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2024,9,28]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/21798\/3633","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/21798\/3633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T14:24:03Z","timestamp":1728656643000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/21798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,28]]},"references-count":0,"journal-issue":{"issue":"10 (Supple-08)","published-online":{"date-parts":[[2024,9,28]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma-bagh-16-21","relation":{},"ISSN":["0030-9982","0030-9982"],"issn-type":[{"type":"electronic","value":"0030-9982"},{"type":"print","value":"0030-9982"}],"subject":[],"published":{"date-parts":[[2024,9,28]]}}}