{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:06:21Z","timestamp":1761897981947},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"10 (Supple-08)","license":[{"start":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T00:00:00Z","timestamp":1727481600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Objective: To assess the role of inflammatory markers ferritin and C- reactive protein as indicators of preeclampsia severity.\r\nMethod: The case-control study was conducted at Al-Yarmouk Teaching Hospital, Baghdad, Iraq, from November 2021 to May 2022, and comprised pregnant women from the obstetrics ward and outpatient clinics aged 16-40 years having a viable singleton pregnancy and gestational age &gt;32 weeks. They were divided into severe preeclampsia group A, non-severe preeclampsia group B and control group C. Serum ferritin and C-reactive protein levels were measured for all the subjects, and compared. Data was analysed using SPSS 26.\r\nResults: Of the 87 pregnant women, 27(31%) were in group A with mean age 29.76\u00b17.53 years and mean gestational age 35.63\u00b11.92 weeks, 29(33.33%) were in group B with mean age 26.83\u00b16.30 years and mean gestational age 36.24\u00b11.72 weeks, and 31(35.63%) were in group C with mean age 26.00\u00b15.73 years and mean gestational age 36.52\u00b11.61 weeks. Ferritin levels in patient groups were significantly higher than in the control group (p&lt;0.05), but it was not significantly different between the patient groups (p&gt;0.05). C-reactive protein levels in the patient groups were significantly higher than in the control group (p&lt;0.05), and they were also significantly higher in group A than in group B (p&lt;0.05). At a cut-off value &gt;101.8 ferritin had sensitivity 92.59% but specificity 20.69%, whereas C- reactive protein at a cut-off value &gt;17.1 had sensitivity 66.67% but specificity 75.86%. \u00a0\r\nConclusion: Serum C- reactive protein level was significantly associated with severity of preeclampsia with an acceptable grade of discriminative ability between severe preeclampsia and non-severe preeclampsia patients.\r\nKey Words: Eclampsia, Protein, Gestational, Ambulatory, Ferritins<\/jats:p>","DOI":"10.47391\/jpma-bagh-16-62","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T14:15:23Z","timestamp":1728396923000},"page":"S274-S277","source":"Crossref","is-referenced-by-count":1,"title":["Serum ferritin and C- reactive protein levels as indicators of severity of preeclampsia"],"prefix":"10.47391","volume":"74","author":[{"family":"Hanan Asaad Ismael","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Abdulkareem Hamady Issa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ban Hadi Hameed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2024,9,28]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/21878\/3726","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/21878\/3726","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T14:15:28Z","timestamp":1728656128000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/21878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,28]]},"references-count":0,"journal-issue":{"issue":"10 (Supple-08)","published-online":{"date-parts":[[2024,9,28]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma-bagh-16-62","relation":{},"ISSN":["0030-9982","0030-9982"],"issn-type":[{"type":"electronic","value":"0030-9982"},{"type":"print","value":"0030-9982"}],"subject":[],"published":{"date-parts":[[2024,9,28]]}}}