{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:06:28Z","timestamp":1776089188539,"version":"3.50.1"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"12","license":[{"start":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T00:00:00Z","timestamp":1731801600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Objective: To estimate the burden of vitamin D deficiency and its association with chronic diseases in patients visiting a private endocrinology clinic in an urban setting.\nMethod: The retrospective study was conducted at the Medicell Institute of Diabetes Endocrinology &amp; Metabolism, Karachi, and comprised medical records of adult patients of either gender between January 2000 and December 2019.Vitamin D status of the patients and its association with various chronic disorders were investigated. Data was analysed using SPSS 21.\nResults: Of the 2,854 patients with mean age 40.87\u00b115.1 years, 2,302(80.7%) were females, and 552(19.3%) were males. There were 1055(37%) patients with vitamin D deficiency, 1,040(36.7%) with severe deficiency, 462(16.2%) with insufficiency, 295(10.3%) with normal status, and 2(0.1%) with vitamin D toxicity. Vitamin D deficiency was observed more frequently in those aged&lt;40 years, and the deficiency was significantly related to type 2 diabetes, impaired glucose tolerance, dyslipidaemia and autoimmune disorders (p&lt;0.05).\nConclusion: The burden of vitamin Deficiency was found to be alarmingly high at a private endocrine and medicine clinic serving a middle and upper socioeconomic class population in an urban setting.\nKey Words: Vitamin D deficiency, Metabolic disorder, Diabetes mellitus, Hypertension.<\/jats:p>","DOI":"10.47391\/jpma.11117","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T14:20:53Z","timestamp":1732112453000},"page":"2107-2113","source":"Crossref","is-referenced-by-count":1,"title":["Vitamin D status of patients visiting a private endocrinology clinic: a retrospective analysis from Karachi, Pakistan"],"prefix":"10.47391","volume":"74","author":[{"given":"Tasnim","family":"Ahsan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saima","family":"Ghaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erum","family":"Sohail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wasfa","family":"Aijaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Uzma Erum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Samar Abbas Jaffri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2024,11,17]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/11117\/3810","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/11117\/3810","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T14:20:54Z","timestamp":1732112454000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/11117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,17]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,11,20]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.11117","relation":{},"ISSN":["0030-9982","0030-9982"],"issn-type":[{"value":"0030-9982","type":"electronic"},{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,17]]}}}