{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T18:36:07Z","timestamp":1766687767741,"version":"3.48.0"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"01","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Objective: To assess the effect of iron therapy on fatigue symptoms in non-anaemic iron-deficient women of reproductive age.\nMethod: The double-blind placebo-controlled randomised trial was conducted at the department of Obstetrics &amp; Gynaecology Central Park Teaching Hospital, Lahore from March 2023 to February 2024 and comprised women aged 18-45 years who were non-anaemic, had haemoglobin level &gt;11g\/dl a fatigue score of at least 36, and a low serum ferritin level. Socio-demographic data was recorded. The subjects were randomised into Group 1 receiving iron therapy and group 2 receiving placebo. After 2 months of intervention, the fatigue scores, haemoglobin and serum ferritin levels were assessed again, and compared with baseline values. Data was analysed using SPSS 26.\nResults: Of the 164 subjects, 86(52.4%) were in Group 1 with mean age 30.70+18.123 years, and 78(47.6%) were in Group 2 with mean age 29.46+7.99 years (p=0.325). In Group 1, significant decrease in fatigue score and significant increase in ferritin and haemoglobin levels were noted post-intervention (p=0.05).\nConclusion: Iron supplementation alleviated fatigue and enhanced serum ferritin concentration in non-anaemic, iron-deficient women of childbearing age.\nKey Words: Fatigue, Iron deficiency, Reproductive age, Haemoglobin, Iron therapy.<\/jats:p>","DOI":"10.47391\/jpma.22068","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T18:32:51Z","timestamp":1766687571000},"page":"4-7","source":"Crossref","is-referenced-by-count":0,"title":["Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age"],"prefix":"10.47391","volume":"76","author":[{"family":"Nayyer Sultana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Fariha Aslam Bajwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Mirza Zeeshan Sikandar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Muhammad Mahtab Haider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Tayyaba Majeed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2025,12,20]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/22068\/4538","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/22068\/4538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T18:32:51Z","timestamp":1766687571000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/22068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,20]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,12,25]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.22068","relation":{},"ISSN":["0030-9982","0030-9982"],"issn-type":[{"value":"0030-9982","type":"electronic"},{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,20]]}}}