{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T15:47:09Z","timestamp":1770738429252,"version":"3.49.0"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"02","license":[{"start":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>The flavonoids are polyphenolic plant products,characterized by a 15-carbon skeleton which includes twobenzene rings. Two active flavonoids, diosmin andhesperidin, are used as venotonic and vasculoprotectiveagents in clinical practice. They are indicated for themanagement of varicose veins, chronic venousinsufficiency and haemorrhoids. They help improvecirculatory tone, reduce inflammation, strengthen venouswalls, and alleviate symptoms such as discomfort, pain andswelling. In this communication, we explore their potentialuse in obesity, especially obesity related oedema(obestasis).Keywords: Daflon, lymphatic, obesity, oedema,overweight, venous disorders<\/jats:p>","DOI":"10.47391\/jpma.26-12","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T18:36:53Z","timestamp":1769711813000},"page":"267-268","source":"Crossref","is-referenced-by-count":0,"title":["The Flavonoids Hesperidin and Diosmin: Adjuvant Therapy for Obesity"],"prefix":"10.47391","volume":"76","author":[{"family":"Sanjay Kalra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Atul Dhingra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Suneet Kumar Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Nitin Kapoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2026,1,27]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/40350\/4625","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/40350\/4625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T18:39:59Z","timestamp":1770575999000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/40350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,27]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2026,1,29]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.26-12","relation":{},"ISSN":["0030-9982","0030-9982"],"issn-type":[{"value":"0030-9982","type":"electronic"},{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,27]]}}}