{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T05:12:47Z","timestamp":1778303567714,"version":"3.51.4"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"05","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Invasive lobular carcinoma (ILC) is the second most common breast carcinoma, accounting for 10% to 15% of invasive breastcarcinomas. ILC is more difficult to diagnose on breast imaging including mammography, ultrasound, and MRI. We report acase of 39 year old female with newly diagnosed left breast ILC (ER+, PR+, HER2). Mammography revealed a single irregulardense mass in the upper central quadrant. Conventional bone scintigraphy demonstrated no evidence of skeletalmetastases. However, whole-body 68Ga FAPI PET\/CT revealed a markedly different disease burden. This case highlights theadded diagnostic value of 68Ga FAPI PET\/CT in detecting the true extent of ILC, particularly when conventional imagingappears limited.\nKeywords: Lobular breast cancer; 68Ga-FAPI PET\/CT; Fibroblast activation protein; cancer-associated fibroblasts; FAPI PET\/CT;breast cancer<\/jats:p>","DOI":"10.47391\/jpma.26-40","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:10:20Z","timestamp":1777662620000},"page":"795-796","source":"Crossref","is-referenced-by-count":0,"title":["68Ga - FAPI PET\/CT Unmasks Extensive Metastatic Invasive Lobular Breast Cancer when Conventional Imaging Falls Short"],"prefix":"10.47391","volume":"76","author":[{"family":"Sharjeel Usmani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Khulood Al Riyami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Anjali Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Badriya Al-Qassabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Marwa Mamdouh Youssef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2026,5,1]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/41465\/4792","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/download\/41465\/4792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T04:50:51Z","timestamp":1778302251000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpma.org.pk\/index.php\/public_html\/article\/view\/41465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,1]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2026,5,1]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.26-40","relation":{},"ISSN":["0030-9982"],"issn-type":[{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,1]]}}}