{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:57:40Z","timestamp":1781207860574,"version":"3.54.1"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"06","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Obesity is a multifactorial endocrine disease. Novelhormone receptor modulators are now available for itstreatment. This does not mean, however, that obesity canbe managed or cured by pharmacotherapy alone.Multidimensional support and scaffolding are required toattain and sustain optimal outcomes with drug therapy. Inthis communication, we provide a systematic coverage ofthe various aspects of support that are needed. We termthem metapharmacologic, as they extend beyond therealm of conventional pharmacology. These includebiomedical (medical, endocrine, pharmacotherapeutic),lifestyle (nutrition, physical activity), and psychosocial(psychological, social, systemic) optimization.Keyword: Holistic care, Lifestyle medicine, nonpharmacologicalcare, overweight, obesity,person-centred care<\/jats:p>","DOI":"10.47391\/jpma.26-45","type":"journal-article","created":{"date-parts":[[2026,5,31]],"date-time":"2026-05-31T19:18:09Z","timestamp":1780255089000},"page":"969-970","source":"Crossref","is-referenced-by-count":0,"title":["Meta-Pharmacologic Support and Scaffolding for Obesity Therapy"],"prefix":"10.47391","volume":"76","author":[{"family":"Sanjay Kalra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Nitin Kapoor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Saurabh Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"26547","published-online":{"date-parts":[[2026,5,28]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/www.jpma.org.pk\/index.php\/public_html\/article\/download\/41865\/4872","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jpma.org.pk\/index.php\/public_html\/article\/download\/41865\/4872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:28:19Z","timestamp":1781206099000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jpma.org.pk\/index.php\/public_html\/article\/view\/41865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.26-45","relation":{},"ISSN":["0030-9982"],"issn-type":[{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,28]]}}}