{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T09:55:41Z","timestamp":1723110941102},"reference-count":0,"publisher":"Pakistan Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Abstract&#x0D;\nObjectives: This study was aimed to assess maternal vitamin D status during pregnancy and\u00a0 determine the association between maternal 25(OH) D levels with risk of preeclampsia (PE).&#x0D;\nMethods: A cross-sectional study was conducted with 172 pregnant women recruited from JPMC between January and December 2017 who were divided as normotensive (n=80) and pre-eclamptic (n=92) groups. Blood pressure was recorded at 20 and 32 weeks of gestation. Five ml of blood sample was collected at 20 weeks of gestation to assess the vitamin D levels by commercially available ELISA assay.&#x0D;\nResults: \u00a0PE group had a significantly higher systolic (p&lt;0.001) and diastolic (p&lt;0.001) blood pressure at 20 weeks of gestation. Vitamin D levels were reported to be significantly lower (p&lt;0.001) in the PE group (17.97\u00b19.38 ng\/ml) as compared to normotensive group (42.18\u00b125.17 ng\/ml). A strong negative correlation of Vitamin D levels with systolic blood pressure (r=-0.428; p&lt;0.001) and diastolic blood pressure (r= -0.375; p&lt;0.001) was found.&#x0D;\nConclusion: This study found a strong relationship between low vitamin D levels and pre-eclamptic manifestation.&#x0D;\nKeywords: Vitamin D; Pre-eclampsia; Pregnancy; Hypertension.&#x0D;\nContinuous....<\/jats:p>","DOI":"10.47391\/jpma.414","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T15:25:27Z","timestamp":1602861927000},"source":"Crossref","is-referenced-by-count":1,"title":["Association of vitamin D levels with preeclampsia"],"prefix":"10.47391","author":[{"family":"Sana Shahid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Asma Ladak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Syeda Sadia Fatima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Fatima Abid Zaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Sabah Farhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2020,10,15]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"deposited":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:39:21Z","timestamp":1607625561000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.jpma.org.pk\/index.php\/public_html\/article\/view\/1676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,15]]},"references-count":0,"URL":"https:\/\/doi.org\/10.47391\/jpma.414","relation":{},"ISSN":["0030-9982"],"issn-type":[{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10,15]]}}}