{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T15:59:07Z","timestamp":1775059147166,"version":"3.50.1"},"reference-count":0,"publisher":"Pakistan Medical Association","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>The study was designed to compare Rosuvastatin with Atorvastatin in terms of their efficacy to reduce low-density lipoproteins (LDL-C) in patients with type 2 diabetes mellitus. For this purpose, a cross-sectional analytical study was conducted in the OPD of Nishtar Medical Hospital, Multan, for six months. The study enrolled 66 patients who were consecutively allocated for double-blind therapy with 10mg Atorvastatin (n = 33) and 10mg Rosuvastatin (n = 33) for one month. The doses titration was carried up to four months in certain patients who failed to achieve 1998 European LDL-C level in the first month. A significant number of patients who were given 10mg Rosuvastatin matched the 1998 LDL-C goal in compared to the patients with 10mg dose of atorvastatin at one month (51% vs 46%, p&lt; 0.0001) and at four months (94% vs 88%, p&lt;0.05). Conclusively, Rosuvastatin was significantly more efficacious than Atorvastatin in its ability to reduce LDL-C.\nKeywords: LDL-C, Rosuvastatin, Atorvastatin, T2DM, statins.<\/jats:p>","DOI":"10.47391\/jpma.4823","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T17:37:33Z","timestamp":1656351453000},"source":"Crossref","is-referenced-by-count":2,"title":["Comparison of efficiency between Rosuvastatin and Atorvastatin in reducing low-density lipoprotein (LDL-C) in patients with diabetes mellitus"],"prefix":"10.47391","author":[{"given":"Saad","family":"Ahmed Khokhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Rai Muhammad Farooq ur Rehman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Seemal Masood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2022,6,27]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"deposited":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T17:37:33Z","timestamp":1656351453000},"score":1,"resource":{"primary":{"URL":"https:\/\/23.88.38.159:443\/index.php\/public_html\/article\/view\/4823"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.47391\/jpma.4823","relation":{},"ISSN":["0030-9982"],"issn-type":[{"value":"0030-9982","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,27]]}}}