{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:31:10Z","timestamp":1747225870991,"version":"3.40.5"},"reference-count":0,"publisher":"Pakistan Medical Association","issue":"10","license":[{"start":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:00Z","timestamp":1694563200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Pak Med Assoc"],"abstract":"<jats:p>Respected Editor, Beta thalassaemia is an autosomal recessive disorder that leads to abnormal production of functional adult haemoglobin because of either inadequate or absent production of the B globin chain (beta+\/beta0).1 Transfusion-dependent thalassemia (TDT) is a rare and most severe form requiring life-long blood transfusions. To mitigate the effects of TDT, life-long blood transfusions every 2-5 weeks are required, which can elicit transfusion-based reactions and lead to an iron overload state, which can further cause widespread organ damage despite the use of iron chelation therapy.2\nContinue...<\/jats:p>","DOI":"10.47391\/jpma.9532","type":"journal-article","created":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T04:54:48Z","timestamp":1694667288000},"page":"2129-2130","source":"Crossref","is-referenced-by-count":0,"title":["Betibeglogene Autotemcel; A new hope for transfusion dependent beta-thalassaemia"],"prefix":"10.47391","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8765-4776","authenticated-orcid":false,"given":"Hiba Tariq","family":"Wally","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Hassan","family":"Zulfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elahi Sana","family":"Jilani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26547","published-online":{"date-parts":[[2023,9,13]]},"container-title":["Journal of the Pakistan Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/ojs.jpma.org.pk\/index.php\/public_html\/article\/download\/9532\/2685","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ojs.jpma.org.pk\/index.php\/public_html\/article\/download\/9532\/2685","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T04:55:27Z","timestamp":1694926527000},"score":1,"resource":{"primary":{"URL":"https:\/\/ojs.jpma.org.pk\/index.php\/public_html\/article\/view\/9532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,13]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,9,13]]}},"URL":"https:\/\/doi.org\/10.47391\/jpma.9532","relation":{},"ISSN":["0030-9982"],"issn-type":[{"type":"print","value":"0030-9982"}],"subject":[],"published":{"date-parts":[[2023,9,13]]}}}