{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T13:41:16Z","timestamp":1776519676932,"version":"3.51.2"},"reference-count":0,"publisher":"Instituto Nacional Cardovascular - Carlos Alberto Peschiera Carrillo","issue":"2","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["APCyCCV"],"abstract":"<jats:p>\r\n\r\n\r\n\r\nObjetivos: Determinar las caracteri\u0301sticas cli\u0301nicas, de ima\u0301genes y laboratoriales asi\u0301 como la sobrevida al an\u0303o del diagno\u0301stico de pacientes con amiloidosis cardi\u0301aca en un hospital de referencia nacional.\r\nMateriales y me\u0301todos: Estudio de serie de casos. Evaluamos las caracteri\u0301sticas cli\u0301nicas, exa\u0301menes complementarios y supervivencia de pacientes con amiloidosis cardi\u0301aca diagnosticados, tratados y seguidos en el servicio de Cardiologi\u0301a Cli\u0301nica del Instituto Nacional Cardiovascular - INCOR EsSalud.\r\nResultados: Se encontraron 8 pacientes con diagno\u0301stico de amiloidosis cardi\u0301aca. La mediana de la edad fue 64.5 an\u0303os y el 75% de sexo masculino. La etiologi\u0301a fue amiloidosis cardi\u0301aca no especificada (25%), amiloidosis cardi\u0301aca transtiretina (37.5%) y amiloidosis cardi\u0301aca de cadenas ligeras (37.5%). La insuficiencia cardi\u0301aca sintoma\u0301tica (NYHA II-III) fue la presentacio\u0301n inicial ma\u0301s comu\u0301n (87.5%). Las manifestaciones extracardi\u0301acas ma\u0301s frecuentes fueron: neuropati\u0301a sensitivo-motora (62.5%), muscu- loesquele\u0301ticas (37.5%), nefropati\u0301a (25%), si\u0301ndrome de tu\u0301nel carpiano bilateral (25%), gammapati\u0301as monoclonales (25%) y efusio\u0301n pleural refractaria (25%). La sobrevida al an\u0303o fue del 75% y la causa de muerte en los 2 fallecidos fue muerte su\u0301bita.\r\nConclusiones: En este estudio sobre amiloidosis cardi\u0301aca en un centro especializado las manifestaciones cli\u0301nicas ma\u0301s frecuentes fueron la insuficiencia cardi\u0301aca y la neuropati\u0301a sensitivo-motora. La mortalidad fue del 25% al an\u0303o, y en todos los casos como muerte su\u0301bita.\r\n\r\n\r\n\r\n<\/jats:p>","DOI":"10.47487\/apcyccv.v1i2.40","type":"journal-article","created":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T17:41:52Z","timestamp":1599241312000},"page":"95-104","source":"Crossref","is-referenced-by-count":2,"title":["Amiloidosis card\u00edaca: Experiencia en un Instituto Cardiovascular de referencia nacionaI"],"prefix":"10.47487","volume":"1","author":[{"given":"Juan Manuel","family":"Mu\u00f1oz Moreno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"A\u00f1orga Ocmin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Espinola Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Alarco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26947","published-online":{"date-parts":[[2020,7,9]]},"container-title":["Archivos Peruanos de Cardiolog\u00eda y Cirug\u00eda Cardiovascular"],"original-title":[],"link":[{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/download\/40\/43","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/download\/40\/43","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,4]],"date-time":"2020-09-04T17:41:57Z","timestamp":1599241317000},"score":1,"resource":{"primary":{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/view\/40"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,9]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,7,13]]}},"URL":"https:\/\/doi.org\/10.47487\/apcyccv.v1i2.40","relation":{},"ISSN":["2708-7212"],"issn-type":[{"value":"2708-7212","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,9]]}}}