{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:34:23Z","timestamp":1747226063626,"version":"3.40.5"},"reference-count":0,"publisher":"Instituto Nacional Cardovascular - Carlos Alberto Peschiera Carrillo","issue":"2","license":[{"start":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T00:00:00Z","timestamp":1656547200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Peru Cardiol Cir Cardiovasc"],"abstract":"<jats:p>La amiloidosis es una enfermedad multisist\u00e9mica por infiltraci\u00f3n de prote\u00ednas mal plegadas, la afectaci\u00f3n card\u00edaca determina su pron\u00f3stico. Existen varios tipos de prote\u00ednas precursoras capaces de causar la enfermedad; sin embargo, solo dos afectan al coraz\u00f3n, por cadenas ligeras de inmunoglobulina clonales (AL) y prote\u00edna tetram\u00e9rica transtiretina (TTR). Es una enfermedad subdiagnosticada y que, en etapas tard\u00edas, es de mal pron\u00f3stico. Se presenta el caso de un paciente adulto mayor con manifestaciones card\u00edacas y extracard\u00edacas progresivas, as\u00ed como criterios laboratoriales y ecocardiogr\u00e1ficos que nos acercaron al diagn\u00f3stico de amiloidosis card\u00edaca y que adem\u00e1s permiti\u00f3 valorar el pron\u00f3stico. Tuvo una evoluci\u00f3n t\u00f3rpida y con desenlace mortal. Los estudios de anatom\u00eda patol\u00f3gica permitieron confirmar la presunci\u00f3n diagn\u00f3stica.<\/jats:p>","DOI":"10.47487\/apcyccv.v3i2.207","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T18:36:00Z","timestamp":1657564560000},"source":"Crossref","is-referenced-by-count":0,"title":["Amiloidosis card\u00edaca: reporte de caso"],"prefix":"10.47487","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1018-8695","authenticated-orcid":false,"given":"Adriana E.","family":"Vi\u00f1as-Mendieta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3534-5119","authenticated-orcid":false,"given":"Mario B.","family":"Garc\u00eda-Saavedra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"26947","published-online":{"date-parts":[[2022,6,30]]},"container-title":["Archivos Peruanos de Cardiolog\u00eda y Cirug\u00eda Cardiovascular"],"original-title":[],"link":[{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/download\/207\/346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/download\/207\/346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T18:36:12Z","timestamp":1657564572000},"score":1,"resource":{"primary":{"URL":"https:\/\/apcyccv.org.pe\/index.php\/apccc\/article\/view\/207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,6,27]]}},"URL":"https:\/\/doi.org\/10.47487\/apcyccv.v3i2.207","relation":{},"ISSN":["2708-7212"],"issn-type":[{"type":"electronic","value":"2708-7212"}],"subject":[],"published":{"date-parts":[[2022,6,30]]}}}