{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T02:08:23Z","timestamp":1741313303359,"version":"3.38.0"},"reference-count":0,"publisher":"Galenos Yayinevi","issue":"4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turk J Surg"],"accepted":{"date-parts":[[2024,12,4]]},"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold> Hepatic steatosis and gallstones are common in the general population, with risk factors being multifactorial. Experimental studies have shown that cholecystectomy increases hepatic steatosis and leads to non-alcoholic fatty liver disease (NAFLD). In order to evaluate this, the current study was carried out in the department of general surgery at a medical school, in the north of India.<\/jats:p>\n                    <jats:p><jats:bold>Material and Methods:<\/jats:bold> One hundred and three patients awaiting cholecystectomy were selected after written informed consent. Their baseline characteristics were captured preoperatively and thereafter followed at 3<jats:sup>rd<\/jats:sup> month with liver function test (LFT), lipid profile and ultrasound (USG) abdomen.<\/jats:p>\n                    <jats:p><jats:bold>Results:<\/jats:bold> Average age of the patients enrolled was 41.62 \u00b1 13.62 years and mean body mass index (BMI) was 25.96 \u00b1 1.73 kg\/m<jats:sup>2<\/jats:sup> . Total bilirubin (0.56 vs 0.76, p&lt; 0.0001) and direct bilirubin (0.15 vs 0.27, p&lt; 0.0001) decreased significantly post cholecystectomy as compared to preoperative values. Levels of serum glutamic-oxaloacetic transaminase (SGOT) (49.14 vs 34.98 IU\/dL), serum glutamic-pyruvic transaminase (SGPT) (50.85 vs 35.46 IU\/dL) and alkaline phosphatase (ALP) (101.16 vs 85.97 IU\/dL) increased significantly post-surgery. Cholesterol values (146.28 vs 168.77 mg\/dL), triglycerides (TGs) (119 vs 133.56 mg\/dL), low density lipoprotein (LDL) (93.32 vs 113.05 mg\/dL) and very low density lipoprotein (VLDL) (18.68 vs 27.45 mg\/dL) decreased significantly while high density lipoprotein (HDL) (48.96 vs 42.42 mg\/dL) increased significantly at three month follow-up. Prevalence of fatty liver increased post operatively with a rise in Grade 1 steatosis (75%). Severity of fatty liver increased with (8.73%) Grade 3 steatosis on USG post-surgery. Hence, new patients with formerly normal USG reports developed fatty liver and those with preexisting liver steatosis seemed to worsen.<\/jats:p>\n                    <jats:p><jats:bold>Conclusion:<\/jats:bold> The study concluded that the prevalence of fatty liver increased post-cholecystectomy. Lipid profile parameters improved favorably with a decline in total cholesterol, TG, LDL and VLDL versus increase in HDL. LFT parameters also changed significantly.<\/jats:p>","DOI":"10.47717\/turkjsurg.2024.6593","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T14:36:41Z","timestamp":1735310201000},"page":"320-327","source":"Crossref","is-referenced-by-count":0,"title":["The effect of cholecystectomy for symptomatic gall stone disease on hepatic steatosis using transabdominal ultrasonography: An observational prospective study"],"prefix":"10.47717","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9825-3360","authenticated-orcid":false,"given":"Umang","family":"Dhakaria","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0601-2635","authenticated-orcid":false,"given":"Rajesh","family":"Kumar Bansiwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5013-1063","authenticated-orcid":false,"given":"Agrawal","family":"Kavita Khemchand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4931-0686","authenticated-orcid":false,"given":"Rajeev","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5323-460X","authenticated-orcid":false,"given":"Mandeep","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7374-329X","authenticated-orcid":false,"given":"Narinder","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6814-0726","authenticated-orcid":false,"given":"Seema","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2811","published-online":{"date-parts":[[2024,12,27]]},"container-title":["Turkish Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/turkjsurg.com\/full-text-pdf\/1998\/eng","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/turkjsurg.com\/full-text-pdf\/1998\/eng","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T06:07:57Z","timestamp":1741068477000},"score":1,"resource":{"primary":{"URL":"https:\/\/turkjsurg.com\/articles\/doi\/turkjsurg.2024.6593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,1]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,12,1]]}},"URL":"https:\/\/doi.org\/10.47717\/turkjsurg.2024.6593","relation":{},"ISSN":["2564-6850","2564-7032"],"issn-type":[{"type":"print","value":"2564-6850"},{"type":"electronic","value":"2564-7032"}],"subject":[],"published":{"date-parts":[[2024,12,1]]}}}