{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:18:39Z","timestamp":1780471119059,"version":"3.54.1"},"reference-count":0,"publisher":"University of the Philippines Manila","issue":"10","license":[{"start":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:00:00Z","timestamp":1780099200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Med Philipp"],"abstract":"<jats:p>Background. The Philippine Guidelines on Periodic Health Examination (PHEX) support the Universal Health Care Act by providing guidance on quality, accessible, and affordable screening services for Filipinos. Conditions that develop in the prenatal period are a major cause of neonatal deaths in the Philippines and account for 14% of deaths in children under five.\nObjectives. This guideline aims to provide evidencebased recommendations for screening prenatal disorders among asymptomatic, pregnant Filipino women. It also aims to equip general practitioners, obstetricsgynecology specialists, allied health professionals, patients, policymakers, regulatory agencies, and healthcare institutions with tools and guidance that facilitate informed, evidence-based healthcare decisions\u00a0for pregnant women.\nMethods. The development of this CPG followed the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to CPG development recommended in the Department of Health (DOH) Manual. Recommendations were finalized using the Evidence-to-Decision (EtD) framework. Evidence Review Experts conducted a systematic literature search and critically appraised recent local and international clinical guidelines. When necessary, they conducted de novo systematic reviews. Information on the benefits and harms of screening, cost-effectiveness, patient values and preferences, acceptability, feasibility, and its impact on equity was obtained. A multisectoral consensus panel reviewed the evidence and developed recommendations. A user-friendly web application and engagement with stakeholders for promotion and implementation were among the dissemination strategies. Experts conducted an external review to provide feedback on the methodology and recommendations.\nResults. Eleven recommendations for different screening\u00a0strategies to improve the health outcomes of pregnant\u00a0women and neonates were developed. This CPG\u00a0contains recommendations for the screening for maternal\u00a0thyroid disease, gestational diabetes mellitus, group\u00a0B Streptococcus infection, fetal aneuploidy, risk for preeclampsia,\u00a0iron deficiency anemia, and undernutrition,\u00a0and conducting cervical length measurements, first-trimester\u00a0ultrasound, and second-trimester ultrasound.\nConclusion. This CPG provides 11 evidence-based recommendations. Applicability in the local setting was carefully considered through the involvement of different stakeholders. The recommendations herein shall hold until new evidence on screening, diagnosing, or managing various risk factors and diseases emerges, or contingencies dictate updating this CPG. This guideline will be updated after three (3) years.<\/jats:p>","DOI":"10.47895\/amp.v60i10.13595","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:46:37Z","timestamp":1780469197000},"source":"Crossref","is-referenced-by-count":0,"title":["Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Prenatal Disorders"],"prefix":"10.47895","volume":"60","author":[{"given":"Maria Julieta Corazon V.","family":"Germar, MD, DHPEd","sequence":"first","affiliation":[{"name":"College of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea Roselle O.","family":"De Castro, MD","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma. Sergia Fatima C.","family":"Sucaldito, MD","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso Syoei R.","family":"Yoshida, MD","sequence":"additional","affiliation":[{"name":"AMOSUP Seamen\u2019s Hospital \u2013 Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lester Sam A.","family":"Geroy, MD, MPH, MSc","sequence":"additional","affiliation":[{"name":"Philippine Society of Public Health Physicians (PSPHP), Inc., Para\u00f1aque City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvie","family":"Udaundo Estrada, RM, BSN, BSM, MPH","sequence":"additional","affiliation":[{"name":"Integrated Midwives Association of the Philippines, Pangasinan, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisy Evangeline C.","family":"Garcia, MD","sequence":"additional","affiliation":[{"name":"Ilocos Training and Regional Medical Center, La Union, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand B.","family":"Sta. Ana, Jr., MD, MPH","sequence":"additional","affiliation":[{"name":"Municipal Health Office, Narra, Palawan, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine Therese R.","family":"Elises-Molon, MD","sequence":"additional","affiliation":[{"name":"Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla Kristine","family":"Silverio-Fernando, MD","sequence":"additional","affiliation":[{"name":"Manila Doctors Hospital, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa L.","family":"Velayo, MD, PhD","sequence":"additional","affiliation":[{"name":"College of Medicine, University of the Philippines Manila, Manila, Philippines"},{"name":"Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara Marie","family":"David\u2013Bustamante, MD","sequence":"additional","affiliation":[{"name":"Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo-Ann L.","family":"Diosana","sequence":"additional","affiliation":[{"name":"Action for Economic Reforms (AER), Quezon City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Asuncion A.","family":"Silvestre, MD","sequence":"additional","affiliation":[{"name":"Kalusugan ng Mag-Ina, Inc., (KMI), Quezon City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Gene D.","family":"Cruz MD","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes Paolo B.","family":"Cerrado, MD, MSc","sequence":"additional","affiliation":[{"name":"Policy and Practice Research Group, Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew Rufino C.","family":"Villafuerte, MD","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lia M.","family":"Palileo-Villanueva, MD, MSc","sequence":"additional","affiliation":[{"name":"College of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherri Ann L.","family":"Suplido, MD","sequence":"additional","affiliation":[{"name":"Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma. Susan B.","family":"Villaluz, MD","sequence":"additional","affiliation":[{"name":"Cebu Puericulture Center and Maternity House, Inc., Cebu, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike Justin A.","family":"Gianan, MD, MPH","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endrik H.","family":"Sy, MD","sequence":"additional","affiliation":[{"name":"Baguio General Hospital and Medical Center, Benguet, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betha Fe M. Castillo, MD","family":"Betha Fe M. Castillo, MD","sequence":"additional","affiliation":[{"name":"Dagupan Doctors Villaflor Memorial Hospital, Pangasinan, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Potre Mairasna P.","family":"Boransing, MD","sequence":"additional","affiliation":[{"name":"Amai Pakpak Medical Center, Marawi City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen B.","family":"De Peralta-Yambao, MD","sequence":"additional","affiliation":[{"name":"Cotabato Regional and Medical Center, Cotabato City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Theresa G.","family":"Cacas, MD","sequence":"additional","affiliation":[{"name":"University of the East Ramon Magsaysay Medical Center, Quezon City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Jefferson V.","family":"Besa, MD, MPH","sequence":"additional","affiliation":[{"name":"College of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella Mae I.","family":"Masamayor, RN, MD","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greco Mark B.","family":"Malijan, MD, MSc","sequence":"additional","affiliation":[{"name":"Clinical Trial Service and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cary Amiel G.","family":"Villanueva, MD, MPH","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myzelle Anne J.","family":"Infantado-Alejandro, PTRP","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of the Philippines Manila, Manila, Philippines"},{"name":"De La Salle Medical and Health Sciences Institute, Dasmari\u00f1as City, Cavite, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27557","published-online":{"date-parts":[[2026,5,30]]},"container-title":["Acta Medica Philippina"],"original-title":[],"link":[{"URL":"https:\/\/actamedicaphilippina.upm.edu.ph\/index.php\/acta\/article\/download\/13595\/7152","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actamedicaphilippina.upm.edu.ph\/index.php\/acta\/article\/download\/13595\/7152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:46:37Z","timestamp":1780469197000},"score":1,"resource":{"primary":{"URL":"https:\/\/actamedicaphilippina.upm.edu.ph\/index.php\/acta\/article\/view\/13595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,30]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,5,30]]}},"URL":"https:\/\/doi.org\/10.47895\/amp.v60i10.13595","relation":{},"ISSN":["2094-9278","0001-6071"],"issn-type":[{"value":"2094-9278","type":"electronic"},{"value":"0001-6071","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5,30]]}}}