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Epstein-Barr virus (EBV) is a pathogen capable of triggering a systemic immune response and is involved in the occurrence of a wide range of B-cell lymphoproliferative disorders. In systemic autoimmune diseases, EBV infection is suspected to play a central role in pathogenesis. Here, we present a case that was thought to be a systemic autoimmune disease and CNS vasculitis that developed after EBV infection, demonstrating that rituximab is effective for the treatment.<\/jats:p>","DOI":"10.47936\/encephalitis.2021.00143","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T05:43:21Z","timestamp":1636955001000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.47936\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Successful treatment with rituximab for central nervous system vasculitis caused by Epstein-Barr virus-associated lymphoproliferative disorder with immunoglobulin M gammopathy"],"prefix":"10.47936","volume":"2","author":[{"given":"Juhee","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han Sang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-0302","authenticated-orcid":true,"given":"Kon","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27912","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4065\/81.5.693"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1709974"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbacli.2016.05.004"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/535738"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.29.3.719"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.02.017"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.587380"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60069-5"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00211"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.47936\/encephalitis.2021.00066"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1556\/eujmi.1.2011.4.2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24050997"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-014-8496-1"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00109"},{"first-page":"749","volume-title":"Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group","year":"2003","key":"ref15"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2020.08.027"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3233\/ch-131691"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2015-0580"}],"container-title":["encephalitis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/encephalitisjournal.org\/upload\/pdf\/encephalitis-2021-00143.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/encephalitisjournal.org\/journal\/view.php?doi=10.47936\/encephalitis.2021.00143","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/encephalitisjournal.org\/upload\/pdf\/encephalitis-2021-00143.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T23:48:26Z","timestamp":1641772106000},"score":1,"resource":{"primary":{"URL":"http:\/\/encephalitisjournal.org\/journal\/view.php?doi=10.47936\/encephalitis.2021.00143"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,10]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.47936\/encephalitis.2021.00143","relation":{},"ISSN":["2765-4559","2734-1461"],"issn-type":[{"type":"print","value":"2765-4559"},{"type":"electronic","value":"2734-1461"}],"subject":[],"published":{"date-parts":[[2022,1,10]]},"assertion":[{"value":"2021-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-10","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}