{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T14:13:03Z","timestamp":1770991983846,"version":"3.50.1"},"reference-count":0,"publisher":"Care Comm","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2021,10,22]]},"abstract":"<jats:p>Objective: Evaluation of perinatal results in a\u202fset of pregnancies complicated by eclampsia. Methods: Analysis of 67,304\u202fbirths performed at the Department of Gynecology and Obstetrics, Masaryk University, Faculty of Medicine and University Hospital, Brno from 2008\u20132018. During the given period, eclampsia was dia gnosed in 16\u202fmothers (0.2\u2030). The during the time of eclampsia (week of gestation, prepartum, intrapartum, postpartum) fetal and neonatal status (signs of intrauterine distress, pH of the umbilical artery, Apgar score, intrauterine fetal death, death in the early neonatal period) were evaluated. Symptoms and course of the eclamptic attack, maternal comorbidities, associated obstetric complications (placental abruption, surgical complications, blood loss, hysterectomy) and non-obstetric complications (coagulopathy, renal and hepatic impairment, neurological complications) were monitored. Results: Out of a\u202ftotal of 16\u202fcases of eclampsia, 13\u202fcases (81.3%) were confi rmed during pregnancy, one case (6.2%) during childbirth, and two cases (12.5%) within 24\u202fhours after childbirth. The mean gestational week of eclampsia was 33\u202fweeks and 3\u202fdays. The typical course of an eclamptic attack characterized by headache and visual disturbances followed by a\u202frapid onset of convulsions was noted in fi ve cases (31%). Fetal hypoxia with a\u202fpH of the umbilical artery less than 7.10\u202foccurred in four cases (25%). The dependence of the decrease in pH value on the time interval from the dia gnosis of eclampsia to the termination of pregnancy was demonstrated. The pH of the umbilical artery decreased on average by 0.054\u202fevery 30\u202fminutes from the onset of the eclamptic attack until the end of pregnancy. There were 3 perinatal deaths in the group (19%). Intrauterine fetal death occurred in one case due to partial abruption of the placenta during an eclamptic attack; two newborns died in the early neonatal period. The cause of death was sepsis in one case and perforation of the intestine in necrotizing enterocolitis in the other. The death of the mother was not recorded in the fi le. The incidence of preeclampsia in subsequent pregnancies reached 18.8%. Non-obstetric and neurological complications (amaurosis, subarachnoid hemorrhage, amnesia) occurred in the group in three cases (18.8%), and renal failure occurred in two cases (12.5%). Conclusion: The incidence of eclampsia at the Department of Gynecology and Obstetrics, Masaryk University, Faculty of Medicine and University Hospital, Brno reached 0.2\u2030 and was stable for a\u202flong time. Associated serious maternal complications occurred in 37.5% of cases and neonatal complications in 31.3% of cases. Early dia gnosis of eclampsia and minimization of the time delay until the end of pregnancy is a\u202fprerequisite for reducing the risk of associated complications. An\u202finterdisciplinary approach is needed. Key words: eclampsia \u2013 convulsions \u2013 urgent conditions in obstetrics \u2013 perinatal outcomes \u2013 hypoxia<\/jats:p>","DOI":"10.48095\/cccg2021297","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T16:56:03Z","timestamp":1636131363000},"page":"297-303","source":"Crossref","is-referenced-by-count":4,"title":["Maternal and neonatal outcomes in pregnancies complicated by eclampsia \u2013 analysis of cases from 2008\u20132018"],"prefix":"10.48095","volume":"86","author":[{"name":"Department of Obstetrics and Gynecology, Medical Faculty of Masaryk University and University Hospital Brno, Czech Republic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Sol\u00e1rov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luk\u00e1\u0161","family":"Hruban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Jank\u016f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romana","family":"Gerychov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Jouzov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"28151","published-online":{"date-parts":[[2021,10,22]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":[],"deposited":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T16:56:04Z","timestamp":1636131364000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2021-5-2\/maternal-and-neonatal-outcomes-in-pregnancies-complicated-by-eclampsia-analysis-of-cases-from-2008-2018-128485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,22]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,10,22]]},"published-print":{"date-parts":[[2021,10,22]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2021297","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"value":"1210-7832","type":"print"},{"value":"1805-4455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,22]]}}}