{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:38:12Z","timestamp":1747226292665,"version":"3.40.5"},"reference-count":0,"publisher":"Care Comm","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2022,4,26]]},"abstract":"<jats:p>Objective: The goal of this article is to present the current knowledge of Klinefelter syndrome and its impact on male reproductive function as well as the current treatment options. Methods: PubMed\/Medline, WoS and Scopus were searched for articles indexed until November 2021. Text: Klinefelter syndrome is a chromosomal aberration with an additional X chromosome in males. This may adversely affect testicular growth and spermatogenesis, thus resulting in male infertility. Recently, new knowledge has appeared about the treatment of male infertility. Conclusion: Interdisciplinary approach enables early diagnosis and treatment of patients with Klinefelter syndrome. Assisted reproductive technology is essential for infertility treatment in patients with Klinefelter syndrome.   Key words: disorders of spermatogenesis \u2013 male sterility \u2013 Klinefelter syndrome \u2013 assisted reproduction \u2013 aneuploidy \u2013 genetic testing<\/jats:p>","DOI":"10.48095\/cccg2022133","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T09:14:24Z","timestamp":1654593264000},"page":"133-136","source":"Crossref","is-referenced-by-count":1,"title":["Assisted reproduction in patients with Klinefelter syndrome"],"prefix":"10.48095","volume":"87","author":[{"name":"Department of Obstetrics and Gynecology, Medical Faculty of Masaryk University and University Hospital Brno, Czech Republic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8043-5543","authenticated-orcid":false,"given":"Karel","family":"Crha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1778-3454","authenticated-orcid":false,"given":"Michal","family":"Je\u0161eta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8797-1894","authenticated-orcid":false,"given":"Radovan","family":"Pilka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3064-4072","authenticated-orcid":false,"given":"Marek","family":"Ka\u0161\u00edk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1839-2802","authenticated-orcid":false,"given":"Lenka","family":"Meki\u0148ov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0446-4454","authenticated-orcid":false,"given":"Jan","family":"Vodi\u010dka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0980-8906","authenticated-orcid":false,"given":"Tom\u00e1\u0161","family":"Crha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"28151","published-online":{"date-parts":[[2022,4,26]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":["Assisted reproduction in patients with Klinefelter syndrome"],"deposited":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T09:14:39Z","timestamp":1654593279000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2022-2-5\/assisted-reproduction-in-patients-with-klinefelter-syndrome-130701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,26]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,4,26]]},"published-print":{"date-parts":[[2022,4,26]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2022133","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"type":"print","value":"1210-7832"},{"type":"electronic","value":"1805-4455"}],"subject":[],"published":{"date-parts":[[2022,4,26]]}}}