{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:08:35Z","timestamp":1790611715075,"version":"4.1.0"},"reference-count":0,"publisher":"Care Comm","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2022,8,31]]},"abstract":"<jats:p>Amniotic fluid embolism (AFE) is a rare and often fatal obstetric complication, characterized by sudden cardiovascular collapse, dyspnea, seizures, mental alteration or coma and laboratory and clinically diagnosed disseminated intravascular coagulation (DIC). Patient\u2019s reaction is typically biphasic with initial pulmonary hypertension and right ventricular failure, followed by left ventricular failure during or immediately right after labor. Early recognition of AFE is critical to a successful survival. Aggressive shock management is needed in collaboration with an anesthesiologist. Several aspects of the condition remain a controversy. This review critically examines, from the best available evidence, the current knowledge regarding the epidemiology, pathophysiology, diagnosis, and available treatment of AFE. This diagnosis still determines perinatal morbidity and mortality and potential permanent neurological symptoms for surviving patients.   Key words: amniotic fluid embolism \u2013 disseminated intravascular coagulation \u2013 meconium \u2013 Zinc-coproporphyrin<\/jats:p>","DOI":"10.48095\/cccg2022261","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T12:56:31Z","timestamp":1662555391000},"page":"261-268","source":"Crossref","is-referenced-by-count":7,"title":["Amniotic fluid embolism \u2013 review and multicentric case analysis"],"prefix":"10.48095","volume":"87","author":[{"name":"Institute for Mother and Child Care, 3rd Medical Faculty, Charles University, Prague, Czech Republic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5732-3159","authenticated-orcid":false,"given":"Hynek","family":"He\u0159man","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1771-8196","authenticated-orcid":false,"given":"Ad\u00e9la","family":"Tefr Faridov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6069-1769","authenticated-orcid":false,"given":"Martina","family":"Volfov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7635-402X","authenticated-orcid":false,"given":"Eli\u0161ka","family":"Hostinsk\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"D\u017euponov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8797-1894","authenticated-orcid":false,"given":"Radovan","family":"Pilka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"28151","published-online":{"date-parts":[[2022,8,31]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":["Amniotic fluid embolism \u2013 review and multicentric case analysis"],"deposited":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T12:56:41Z","timestamp":1662555401000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2022-4-6\/amniotic-fluid-embolism-review-and-multicentric-case-analysis-131662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,31]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,8,31]]},"published-print":{"date-parts":[[2022,8,31]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2022261","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"value":"1210-7832","type":"print"},{"value":"1805-4455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,31]]}}}