{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T09:01:28Z","timestamp":1764061288549,"version":"3.28.0"},"reference-count":0,"publisher":"Care Comm","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2024,10,25]]},"abstract":"<jats:p>The authors present a case of 1st trimester miscarriage where an early, complete hydatidiform mole was clinically suspected. Histopathological and immunohistochemical analyses excluded a complete mole, but the histomorphological profile was in concordance with a partial hydatidiform mole. Genetic analysis excluded a partial mole based on biparental genome composition, where further genetic analyses detected trisomy of chromosome 16. Trisomy of chromosome 16 is a frequent cause of 1st trimester abortions and may lead to highly abnormal placental histomorphology mimicking a partial mole. Genetic analyses are crucial for proper differential diagnosis and for the determination of adequate follow-up and prognosis for further pregnancies.   Key words: trisomy 16 \u2013 aneuploidy \u2013 DNA analysis \u2013 placental histomorphology\u202f<\/jats:p>","DOI":"10.48095\/cccg2024396","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:40:32Z","timestamp":1731606032000},"page":"396-399","source":"Crossref","is-referenced-by-count":2,"title":["Advantages of next-generation sequencing (NGS) in the molecular classification of endometrial carcinomas \u2013 our experience with 270 cases"],"prefix":"10.48095","volume":"89","author":[{"name":"Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University Bratislava, Bratislava, Slovak Republic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lajos","family":"Gergely","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miroslav","family":"Korbe\u013e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u013dudov\u00edt","family":"Danihel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanda","family":"Repisk\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miroslav","family":"Tomka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liam","family":"McCullough","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Pri\u0161\u010d\u00e1kov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"28151","published-online":{"date-parts":[[2024,10,31]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":["Advantages of next-generation sequencing (NGS) in the molecular &lt;!-- ============== --&gt; &lt;journal_article publication_type='full_text'&gt;   &lt;titles&gt;     &lt;title&gt;Trisomy 16 mimicking hydatidiform mole&lt;\/title&gt;     &lt;original_language_title&gt;Trisomy 16 mimicking hydatidiform mole"],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T17:40:33Z","timestamp":1731606033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2024-5-5\/trisomy-16-mimicking-hydatidiform-mole-139016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,25]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,10,31]]},"published-print":{"date-parts":[[2024,10,25]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2024396","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"value":"1210-7832","type":"print"},{"value":"1805-4455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,25]]}}}