{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T08:44:44Z","timestamp":1759826684369,"version":"3.41.0"},"reference-count":0,"publisher":"Care Comm","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2025,4,30]]},"abstract":"<jats:p>Due to the implementation of sentinel lymph node ultrastaging, the prevalence of isolated tumor cells and micrometastases have increased. This literature review comprises of articles published between January 2019 and September 2024 aiming at low-volume metastases in regional lymph nodes, their prognosis, and links to molecular classification. Micrometastases are currently considered as having metastatic lymph node involvement; however, they have a better prognosis than macrometastases. Accordingly, therapy is tailored. In contrast, isolated tumor cell presence is not considered metastatic involvement according to International Federation of Gynecology and Obstetrics (FIGO) 2023 staging and does not affect the therapeutic procedure because their significant prognostic importance has not been proven so far. \n\nKey words: low-volume metastasis \u2013 endometrial cancer \u2013 ultrastaging \u2013 isolated tumor cells \u2013 micrometastases \u2013 sentinel lymph node<\/jats:p>","DOI":"10.48095\/cccg2025158","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T07:06:41Z","timestamp":1747984001000},"page":"158-162","source":"Crossref","is-referenced-by-count":1,"title":["Low-volume regional lymph node metastasis in endometrial cancer \u2013 2024 update"],"prefix":"10.48095","volume":"90","author":[{"name":"Department of Obstetrics and Gynecology, Medical Faculty of Masaryk University and University Hospital Brno, Czech Republic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dita","family":"M\u00fcnzov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Bretov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitka","family":"Hausnerov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark\u00e9ta","family":"Bedna\u0159\u00edkov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lubo\u0161","family":"Min\u00e1\u0159","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edt","family":"Weinberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"28151","published-online":{"date-parts":[[2025,4,30]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":[],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T07:06:44Z","timestamp":1747984004000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2025-2-6\/low-volume-regional-lymph-node-metastasis-in-endometrial-cancer-2024-update-140558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,4,30]]},"published-print":{"date-parts":[[2025,4,30]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2025158","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"value":"1210-7832","type":"print"},{"value":"1805-4455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]}}}