{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:08:25Z","timestamp":1785420505504,"version":"3.56.0"},"reference-count":0,"publisher":"Care Comm","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ceska Gynekol"],"published-print":{"date-parts":[[2026,6,26]]},"abstract":"<jats:p>Eclampsia remains one of the most severe obstetric emergencies associated with substantial maternal and perinatal morbidity and mortality. Although classically regarded as a hypertensive complication of pre-eclampsia, atypical presentations without sustained hypertension or severe clinical features may occur, complicating risk prediction and timely intervention. We report a case of atypical eclampsia in a 21-year-old woman hospitalized with a diagnosis of pre-eclampsia without severe features. Despite predominantly normal blood pressure values and initially stable laboratory findings, the sFlt-1\/PlGF ratio and Doppler assessment of the uterine and ophthalmic arteries revealed significant abnormalities. The patient subsequently developed generalized tonic\u2013clonic seizures, requiring urgent obstetric intervention. This case underscores the limitations of conventional diagnostic criteria in identifying patients at risk for sudden neurological deterioration and highlights the potential value of angiogenic biomarkers and targeted Doppler evaluation in refining risk stratification among women with pre-eclampsia. \n\nKey words: eclampsia \u2013 atypical presentation \u2013 sFlt-1\/PlGF ratio \u2013 uterine artery Doppler \u2013 ophthalmic artery Doppler<\/jats:p>","DOI":"10.48095\/cccg2026181","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:05:00Z","timestamp":1785416700000},"page":"181-185","source":"Crossref","is-referenced-by-count":0,"title":["Atypical eclampsia without severe hypertension \u2013 the role of ophthalmic artery Doppler and sFlt-1\/PlGF ratio: a case report"],"prefix":"10.48095","volume":"91","author":[{"given":"Vera","family":"Oom","sequence":"first","affiliation":[{"name":"Service of Gynecology and Obstetrics, Cascais Hospital Dr. Jos\u00e9 de Almeida, Cascais, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constan\u00e7a","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Araujo J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Yano","family":"Callado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Proen\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catarina","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato Augusto","family":"Moreira de S\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filomena","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"28151","published-online":{"date-parts":[[2026,6,26]]},"container-title":["\u010cesk\u00e1 gynekologie"],"original-title":["Atypical eclampsia without severe hypertension \u2013 the role of ophthalmic artery Doppler and sFlt-1\/PlGF ratio: a case report"],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:05:01Z","timestamp":1785416701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cs-gynekologie.cz\/en\/journals\/czech-gynaecology\/2026-3-7\/atypical-eclampsia-without-severe-hypertension-the-role-of-ophthalmic-artery-doppler-and-sflt-1-plgf-ratio-a-case-report-144010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,26]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,6,26]]},"published-print":{"date-parts":[[2026,6,26]]}},"URL":"https:\/\/doi.org\/10.48095\/cccg2026181","relation":{},"ISSN":["1210-7832","1805-4455"],"issn-type":[{"value":"1210-7832","type":"print"},{"value":"1805-4455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,26]]}}}