{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:58:10Z","timestamp":1777892290435,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Royal College of Physicians of Edinburgh"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>Background: Severity of chronic obstructive pulmonary disease (COPD) is based either on symptoms\/disability or lung function, which have no discernible correlation. We hypothesised that impulse oscillometry (IOS), a non-effortdependent measure of central and peripheral airway mechanics, could correlate to dyspnoea in COPD.<\/jats:p>\n                  <jats:p>Methods: We analysed screening data from 57 COPD patients who had spirometry, IOS and Medical Research Council dyspnoea score (MRC) measurements. We searched for predictors or correlations of MRC from IOS, spirometry and demographics.<\/jats:p>\n                  <jats:p>Results: MRC had no significant predictors or correlations from IOS, spirometry or demographics (possibly excepting smoking history, p=0.05). IOS correlated significantly with spirometry: FEV1 and FEF25\u201375 vs. R5\u2013R20 (peripheral airway resistance), r=\u20130.499, p&lt;0.001 and r=\u20130.397, p=0.002 respectively.<\/jats:p>\n                  <jats:p>Conclusion: MRC is not related to IOS or spirometry in COPD. IOS correlates well with spirometry, particularly peripheral airway resistance (R5\u2013R20). IOS is useful, but does not provide a link between symptoms and pulmonary function measurements.<\/jats:p>","DOI":"10.4997\/jrcpe.2012.204","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T06:07:19Z","timestamp":1534140439000},"page":"111-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Relationships between impulse oscillometry, spirometry and dyspnoea in COPD"],"prefix":"10.1177","volume":"42","author":[{"given":"WJ","family":"Anderson","sequence":"first","affiliation":[{"name":"Clinical Research Fellow"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BJ","family":"Lipworth","sequence":"additional","affiliation":[{"name":"Professor of Allergy and Pulmonology; Asthma and Allergy Research Group, University of Dundee, Dundee, Scotland, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,6,1]]},"reference":[{"key":"bibr1-JRCPE.2012.204","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5_suppl.121S"},{"key":"bibr2-JRCPE.2012.204","doi-asserted-by":"crossref","unstructured":"2de Torres JP, Bastarrika G, Zagaceta J  Emphysema presence, severity, and distribution has little impact on the clinical presentation of a cohort of patients with mild to moderate COPD. Chest 2011; 139:36\u201342. http:\/\/dx.doi.org\/10.1378\/chest.10-0984","DOI":"10.1378\/chest.10-0984"},{"key":"bibr3-JRCPE.2012.204","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5213.1665"},{"key":"bibr4-JRCPE.2012.204","unstructured":"4Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of COPD (GOLD) [Internet]. Spain: Global Initiative for Chronic Obstructive Lung Disease; 2010 [cited 2012 May 18]. Available from: http:\/\/www.goldcopd.org\/"},{"key":"bibr5-JRCPE.2012.204","unstructured":"5National Clinical Guidance Centre. Chronic obstructive pulmonary disease: management of chronic obstructive pulmonary disease in adults in primary and secondary care [Internet]. London: National Clinical Guideline Centre; 2010 [cited 2012 May 18]. 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