{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T10:59:08Z","timestamp":1777892348187,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Royal College of Physicians of Edinburgh"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:p>Diagnosis can prove challenging when a patient with a chronic neurological disease presents with acute deterioration. This is especially true in Huntington\u2019s disease, where cognitive impairment is prominent. We present a case of hypercalcaemia causing an acute deterioration in physical and cognitive function in a patient with Huntington\u2019s disease. Similarity in clinical phenotype between hypercalcaemia and Huntington\u2019s disease, as well as failure to appreciate the acute nature of the deterioration resulted in diagnostic delay and prolonged admission. With treatment, the patient improved dramatically. The case highlights key learning points regarding assessment of patients with chronic neurological disease.<\/jats:p>","DOI":"10.4997\/jrcpe.2014.407","type":"journal-article","created":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T10:59:28Z","timestamp":1418813968000},"page":"286-288","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Hypercalcaemia mimicking Huntington\u2019s disease: lessons learned from delayed diagnosis"],"prefix":"10.1177","volume":"44","author":[{"given":"J","family":"Hrastelj","sequence":"first","affiliation":[{"name":"Core Medical Trainee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"McLauchlan","sequence":"additional","affiliation":[{"name":"Neurology Registrar, University Hospital of Wales, Cardiff"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Rosser","sequence":"additional","affiliation":[{"name":"Professor of Neuroscience, Cardiff University, Cardiff;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Clenaghan","sequence":"additional","affiliation":[{"name":"Huntingtons\u2019s disease Specialist Nurse, Cardiff and Vale University Health Board, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,12,1]]},"reference":[{"key":"bibr1-JRCPE.2014.407","first-page":"320","volume":"26","author":"Huntington G.","year":"1872","journal-title":"On chorea"},{"key":"bibr2-JRCPE.2014.407","doi-asserted-by":"crossref","unstructured":"2 Schoenfeld M, Myers RH, Cupples LA  Increased rate of suicide among patients with Huntington\u2019s disease. 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World J Surg 2002; 26: 942\u20139.","DOI":"10.1007\/s00268-002-6623-y"}],"container-title":["Journal of the Royal College of Physicians of Edinburgh"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4997\/JRCPE.2014.407","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.4997\/JRCPE.2014.407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:27:26Z","timestamp":1777616846000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.4997\/JRCPE.2014.407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.4997\/JRCPE.2014.407"],"URL":"https:\/\/doi.org\/10.4997\/jrcpe.2014.407","relation":{},"ISSN":["1478-2715","2042-8189"],"issn-type":[{"value":"1478-2715","type":"print"},{"value":"2042-8189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12]]}}}