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Different explanations for the origin of the accumulating black pigment arose and by the early nineteenth century three hypotheses had emerged: 1) soot inhaled into the lungs from the air; 2) carbon accumulating in the lungs from abnormal pulmonary carbon dioxide metabolism; and, 3) pigment derived from the blood. In 1813 the English physician and chemist George Pearson published a paper in which he described the recovery of the black pigment from lungs and its chemical analysis. Pearson declared the black pigment to be airborne carbon\/soot from the burning of coal and wood. He described these particles depositing in \u2018black spots\u2019 in the terminal airways and accumulating in the peribronchial lymph nodes, forming \u2018black glands'. Despite Pearson's prescient account, debate continued and the true explanation, given in that paper, was not fully accepted until the late nineteenth century.<\/jats:p>","DOI":"10.4997\/jrcpe.2019.219","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T10:51:09Z","timestamp":1560336669000},"page":"165-170","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Black Lungs in the General Population: A New Look at An Old Dispute"],"prefix":"10.1177","volume":"49","author":[{"given":"Ken","family":"Donaldson","sequence":"first","affiliation":[{"name":"Senior Research Fellow, Museums of the Royal College of Surgeons Edinburgh and Emeritus Professor of Respiratory Toxicology, University of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A","family":"Wallace","sequence":"additional","affiliation":[{"name":"Professor and Consultant Pathologist, Royal Infirmary of Edinburgh and Division of Pathology, University of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Henry","sequence":"additional","affiliation":[{"name":"Director of Heritage, Surgeons\u2019 Hall Museums, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Seaton","sequence":"additional","affiliation":[{"name":"Emeritus Professor of Environmental Medicine, University of Aberdeen, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,6,1]]},"reference":[{"key":"bibr1-jrcpe.2019.219","unstructured":"Laennec RTH. 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