{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:51:13Z","timestamp":1757778673128,"version":"3.40.4"},"reference-count":18,"publisher":"Jaypee Brothers Medical Publishing","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2022,11,7]]},"abstract":"<jats:p>Background: Temporal lobe epilepsy (TLE) is the most common cause of partial seizures. However,  there is a paucity of data on the correlation of clinical and semiological features of TLE with specific  imaging findings on magnetic resonance imaging (MRI). Objective: In this study, we sought to evaluate the association between the semiology of TLE with  specific etiological findings as identified on MRI. Materials and methods: This was a single-center, observational study in which consecutive patients  presenting with clinical features diagnostic of TLE underwent a brain MRI on a 1.5 T scanner. The  data collected from the various MR parameters were then correlated with history. Results: A total of 90 patients were included in the study. The mean age of the study population  was 29.1 years. Females comprised 45% of the study population. Mesial temporal sclerosis (MTS)  was the most common imaging finding in about 60% of patients. Four out of five patients had  aura whereas 70% had automatisms. The presence of aura in TLE patients was significantly associated with MTS on MRI (p = 0.042).  The presence of automatism and history of childhood febrile seizure did not have a significant  association with any specific etiological findings on MRI (p = 0.254 and 0.731, respectively).  Drug-refractory epilepsy was commonly associated with the presence of MTS on MRI (p = 0.004).  The presence of dual pathology on MRI was associated with drug-refractory epilepsy (p = 0.031). Conclusions: The presence of aura and drug-refractory epilepsy point towards the presence of  MTS. Dual pathology, on MRI, in TLE patients may be a risk factor for drug-refractory epilepsy<\/jats:p>","DOI":"10.5005\/japi-11001-0125","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T08:10:32Z","timestamp":1667376632000},"page":"13-17","source":"Crossref","is-referenced-by-count":1,"title":["Association between Clinical Features and Magnetic Resonance Imaging Findings in Patients with Temporal Lobe Epilepsy"],"prefix":"10.59556","volume":"70","author":[{"given":"Vineeta","family":"Ojha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avinash","family":"Mani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debasis","family":"Basu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Bhadra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2022,11,1]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"Blair RDG. 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J Neurol 2002;249(12):1651-1658.","DOI":"10.1007\/s00415-002-0843-9"}],"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T10:56:44Z","timestamp":1745578604000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/files\/JAPI0125_p13-17_compressed.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":18,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022,11,1]]},"published-print":{"date-parts":[[2022,11,7]]}},"URL":"https:\/\/doi.org\/10.5005\/japi-11001-0125","relation":{},"ISSN":["0004-5772"],"issn-type":[{"type":"print","value":"0004-5772"}],"subject":[],"published":{"date-parts":[[2022,11,1]]}}}