{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T03:17:53Z","timestamp":1752549473068,"version":"3.40.4"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2022,12,7]]},"abstract":"<jats:p>infections and the emergence of bacterial resistance is common among patients in the intensive  care units (ICUs). The aim of the study is to identify the common bacterial pathogen isolated from  an endotracheal (ET) aspirate and its antibiotic susceptibility pattern. Materials and methods: A prospective analytical study was carried out in a tertiary care hospital  for a period of 1 year. All ET aspirate sample sent to the microbiology laboratory was processed and  identified by standard biochemical tests and antibiotic sensitivity was by disk diffusion method  as per Clinical and Laboratory Standards Institute (CLSI) guidelines. Results: Of the total 217 samples studied, 85 (39.17.1%) were culture sterile and 132 (60.82%)  showed culture positive. Among 132 isolates, the predominant organism was Acinetobacter baumannii (36.36%) followed by Klebsiella pneumoniae (24.24%) and Pseudomonas aeruginosa (20.45%). We have reported a higher percentage of resistance among the isolated gram-negative  bacilli to carbapenems, aminoglycosides, and third-generation cephalosporins, with increased  sensitivity to piperacillin-tazobactam and cefoperazone-sulbactam. Conclusion: In our study, A. baumannii was the predominantly isolated gram-negative bacilli  followed by K. pneumoniae and P. aeruginosa. One of the rising concerns to hospital-acquired  respiratory pathogens is the surge of multidrug resistance patterns. Hence, strict adherence to  antibiotic policy and appropriate use according to the guidelines will save the use of drugs in the  future in life-threatening conditions.<\/jats:p>","DOI":"10.5005\/japi-11001-0143","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T06:31:32Z","timestamp":1681281092000},"page":"13-15","source":"Crossref","is-referenced-by-count":1,"title":["Antibiotic Susceptibility Pattern of Aerobic Bacterial Pathogen Isolated from Endotracheal Aspirate"],"prefix":"10.59556","volume":"70","author":[{"given":"Swetha","family":"S","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramodhini","family":"S","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umadevi","family":"S","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshy M","family":"Easow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2022,12,1]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T10:57:23Z","timestamp":1745578643000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/files\/JAPI0143_p13-15.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2022,12,7]]}},"URL":"https:\/\/doi.org\/10.5005\/japi-11001-0143","relation":{},"ISSN":["0004-5772"],"issn-type":[{"type":"print","value":"0004-5772"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}