{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:33:29Z","timestamp":1787312009458,"version":"build-2736575974"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2022,12,7]]},"abstract":"<jats:p>Introduction: In half of the individuals with systemic lupus erythematosus (SLE), over the course  of the disease, pulmonary involvement occurs frequently and is one of the parts in the array  of presenting symptoms. But the published research and information on SLE have historically  concentrated on renal, central nervous system (CNS), and dermatological manifestations, while  the pulmonary effects of SLE have received very less attention. Objective: To know the extent and pattern of pulmonary involvement in SLE patients in a tertiary  care hospital. Materials and methods: A cross-sectional observational study was conducted among  70 diagnosed SLE [who fulfilled the revised American College of Rheumatology (ACR) criteria  for the classification of SLE] patients attending a tertiary care center. Seventy diagnosed SLE  patients who met the updated ACR criteria for the classification of SLE and were enrolled in a  tertiary care facility in West Bengal participated in a cross-sectional observational study. After  informed consent, clinical examinations, general survey, respiratory examination, cardiovascular  examination, and relevant investigations [chest X-ray, pulmonary function test, echocardiography  and electrocardiography, and high-resolution computed tomography (HRCT)\/chest computed  tomography (CT) scan] were performed. Results: The majority of the study subjects belonged to the 21\u201330 years of age-group (45.7%) and  were females. Most of the study subjects were treatment-na\u00efve as they were newly diagnosed.  Among the chief presenting complaints, the most common was cough followed by dyspnea  and pleuritic chest pain. Chest X-rays showed pleural pathology in 37% of study subjects and  pulmonary function tests were found to have a restrictive pattern in 4.3%. Echocardiography  documented that 19.6% had pulmonary artery hypertension. HRCT revealed that 19.4% of subjects  had definitive findings of interstitial lung diseases (ILD). Conclusion: A substantial contributor to morbidity and death, SLE is a potentially fatal, commonly  debilitating autoimmune illness with pulmonary symptoms. Cough was the most common  presenting complaint, and the most common radiological abnormality detected was pleural  effusion. Spirometry revealed, as expected, a restrictive pattern in most of the cases. Around 29%  of cases revealed features suggestive of or confirmatory evidence for intestinal lung disease. As a  whole, the prevalence of lung involvement in SLE in the study was 67%. But this being a study with only 70 participants, a further longitudinal is recommended to study  disease activity correlation with the incidence of early pulmonary involvement in SLE disease  course.<\/jats:p>","DOI":"10.5005\/japi-11001-0148","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T02:31:32Z","timestamp":1681266692000},"page":"58-61","source":"Crossref","is-referenced-by-count":3,"title":["Pulmonary Involvement in Systemic Lupus Erythematosus Patients in a Tertiary Care Hospital"],"prefix":"10.59556","volume":"70","author":[{"given":"Dibyayanam","family":"Sahu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandip","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharmistha","family":"Bhattacherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saikat","family":"Datta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smarajit","family":"Banik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2914","published-online":{"date-parts":[[2022,12,1]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T06:57:24Z","timestamp":1745564244000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/files\/JAPI0148_p58-61.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2022,12,7]]}},"URL":"https:\/\/doi.org\/10.5005\/japi-11001-0148","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12,1]]}}}