{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:32:13Z","timestamp":1787164333116,"version":"build-2736575974"},"reference-count":40,"publisher":"The Editorial Office of Gut and Liver","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gut Liver"],"published-print":{"date-parts":[[2015,11,23]]},"DOI":"10.5009\/gnl15077","type":"journal-article","created":{"date-parts":[[2015,10,26]],"date-time":"2015-10-26T23:12:29Z","timestamp":1445901149000},"page":"707","source":"Crossref","is-referenced-by-count":13,"title":["The Expanding Role of Contrast-Enhanced Endoscopic Ultrasound in Pancreatobiliary Disease"],"prefix":"10.5009","volume":"9","author":[{"given":"Jun-Ho","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Wan","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2920","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"9976","DOI":"10.3748\/wjg.v20.i29.9976","article-title":"Endoscopic ultrasound in the diagnosis and treatment of pancreatic disease","volume":"20","author":"Teshima, CW","year":"2014","journal-title":"World J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1055\/s-0032-1308909","article-title":"Contrast-enhanced harmonic endoscopic ultrasound","volume":"44","author":"S\u0103ftoiu, A","year":"2012","journal-title":"Endoscopy"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4253\/wjge.v6.i4.121","article-title":"Current status and future applications of contrast-enhanced endoscopic ultrasonography","volume":"6","author":"Yip, HC","year":"2014","journal-title":"World J Gastrointest Endosc"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3748\/wjg.v17.i1.42","article-title":"Contrast-enhanced endoscopic ultrasonography","volume":"17","author":"Reddy, NK","year":"2011","journal-title":"World J Gastroenterol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s00535-012-0662-4","article-title":"Contrast-enhanced endoscopic ultrasonography in digestive diseases","volume":"47","author":"Sumi, H","year":"2012","journal-title":"J Gastroenterol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ultrasmedbio.2005.09.008","article-title":"Disposition of perfluorobutane in rats after intravenous injection of Sonazoid","volume":"32","author":"Toft, KG","year":"2006","journal-title":"Ultrasound Med Biol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1007\/s11517-009-0507-3","article-title":"Safety and bio-effects of ultrasound contrast agents","volume":"47","author":"ter Haar, G","year":"2009","journal-title":"Med Biol Eng Comput"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.ultrasmedbio.2006.05.031","article-title":"The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations","volume":"32","author":"Piscaglia, F","year":"2006","journal-title":"Ultrasound Med Biol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.giec.2012.04.013","article-title":"Endoscopic ultrasound: contrast enhancement","volume":"22","author":"Kitano, M","year":"2012","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1055\/s-2005-858662","article-title":"Contrast-enhanced endoscopic ultrasound with low mechanical index: a new technique","volume":"43","author":"Dietrich, CF","year":"2005","journal-title":"Z Gastroenterol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1055\/s-0031-1281676","article-title":"The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): update 2011 on non-hepatic applications","volume":"33","author":"Piscaglia, F","year":"2012","journal-title":"Ultraschall Med"},{"key":"ref12","first-page":"375","article-title":"Pancreatic cancer: diagnosis and endoscopic staging","volume":"14","author":"Galasso, D","year":"2010","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00535-005-1598-8","article-title":"Contrast-enhanced sonography of pancreatic carcinoma: correlations with pathological findings","volume":"40","author":"Numata, K","year":"2005","journal-title":"J Gastroenterol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"599","DOI":"10.5009\/gnl.2013.7.5.599","article-title":"Clinical role of contrast-enhanced harmonic endoscopic ultrasound in differentiating solid lesions of the pancreas: a single-center experience in Korea","volume":"7","author":"Lee, TY","year":"2013","journal-title":"Gut Liver"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.gie.2007.07.045","article-title":"A novel perfusion imaging technique of the pancreas: contrast-enhanced harmonic EUS (with video)","volume":"67","author":"Kitano, M","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1055\/s-0034-1365425","article-title":"Diagnosis of pancreatic cancer by contrast-harmonic endoscopic ultrasound (EUS): complementary and not competitive with EUS-guided fine-needle aspiration","volume":"46","author":"Fusaroli, P","year":"2014","journal-title":"Endoscopy"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/ajg.2011.354","article-title":"Characterization of small solid tumors in the pancreas: the value of contrast-enhanced harmonic endoscopic ultrasonography","volume":"107","author":"Kitano, M","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.cgh.2008.02.030","article-title":"Improved differentiation of pancreatic tumors using contrast-enhanced endoscopic ultrasound","volume":"6","author":"Dietrich, CF","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.cgh.2010.04.012","article-title":"Contrast harmonic echo-endoscopic ultrasound improves accuracy in diagnosis of solid pancreatic masses","volume":"8","author":"Fusaroli, P","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"246","DOI":"10.3748\/wjg.v12.i2.246","article-title":"Contrast-enhanced endoscopic ultrasound in discrimination between focal pancreatitis and pancreatic cancer","volume":"12","author":"Hocke, M","year":"2006","journal-title":"World J Gastroenterol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1055\/s-0034-1364969","article-title":"Contrast-harmonic endoscopic ultrasound for the diagnosis of pancreatic adenocarcinoma: a prospective multicenter trial","volume":"46","author":"Gincul, R","year":"2014","journal-title":"Endoscopy"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.gie.2012.02.051","article-title":"Contrast-enhanced EUS for differential diagnosis of pancreatic mass lesions: a meta-analysis","volume":"76","author":"Gong, TT","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.giec.2013.08.004","article-title":"Future directions in EUS-guided tissue acquisition","volume":"24","author":"Deprez, PH","year":"2014","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1136\/gut.50.5.599","article-title":"You get what you expect? A critical appraisal of imaging methodology in endosonographic cancer staging","volume":"50","author":"Meining, A","year":"2002","journal-title":"Gut"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"732","DOI":"10.3109\/00365521003690269","article-title":"Contrast-enhanced harmonic EUS with novel ultrasonographic contrast (Sonazoid) in the preoperative T-staging for pancreaticobiliary malignancies","volume":"45","author":"Imazu, H","year":"2010","journal-title":"Scand J Gastroenterol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1572-0241.1998.179_b.x","article-title":"Contrast-enhanced endoscopic ultrasonography in pancreatic diseases: a preliminary study","volume":"93","author":"Hirooka, Y","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1055\/s-2007-966391","article-title":"The utility of contrast-enhanced endoscopic ultrasound in monitoring ethanol-induced pancreatic tissue ablation: a pilot study in a porcine model","volume":"39","author":"Giday, SA","year":"2007","journal-title":"Endoscopy"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"158","DOI":"10.5946\/ce.2015.48.2.158","article-title":"Endoscopic ultrasonography-guided ethanol ablation for small pancreatic neuroendocrine tumors: results of a pilot study","volume":"48","author":"Park do, H","year":"2015","journal-title":"Clin Endosc"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1053\/j.gastro.2010.10.001","article-title":"Endoscopic ultrasonography-guided ethanol lavage with paclitaxel injection treats patients with pancreatic cysts","volume":"140","author":"Oh, HC","year":"2011","journal-title":"Gastroenterology"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1097\/SLA.0b013e3181a189a8","article-title":"Intraductal papillary mucinous neoplasms of the pancreas: differentiation of malignant and benign tumors by endoscopic ultrasound findings of mural nodules","volume":"249","author":"Ohno, E","year":"2009","journal-title":"Ann Surg"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1067\/mge.2000.108041","article-title":"A new strategy to predict the neoplastic polyps of the gallbladder based on a scoring system using EUS","volume":"52","author":"Choi, WB","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.gie.2013.03.1328","article-title":"Utility of contrast-enhanced harmonic EUS in the diagnosis of malignant gallbladder polyps (with videos)","volume":"78","author":"Choi, JH","year":"2013","journal-title":"Gastrointest Endosc"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1007\/s00464-012-2620-x","article-title":"Differential diagnosis between gallbladder adenomas and cholesterol polyps on contrast-enhanced harmonic endoscopic ultrasonography","volume":"27","author":"Park, CH","year":"2013","journal-title":"Surg Endosc"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1007\/s10620-014-3115-5","article-title":"Contrast-enhanced harmonic endoscopic ultrasonography in the differential diagnosis of gall-bladder wall thickening","volume":"59","author":"Imazu, H","year":"2014","journal-title":"Dig Dis Sci"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0016-5107(97)70176-7","article-title":"A comparison of the accuracy of echo features during endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration for diagnosis of malignant lymph node invasion","volume":"45","author":"Bhutani, MS","year":"1997","journal-title":"Gastrointest Endosc"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1572-0241.2006.00394.x","article-title":"Usefulness of contrast-enhanced endoscopic ultrasonography in the differentiation between malignant and benign lymphadenopathy","volume":"101","author":"Kanamori, A","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1097\/MCG.0000000000000032","article-title":"Clinical usefulness with the combination of color Doppler and contrast-enhanced harmonic EUS for the assessment of visceral vascular diseases","volume":"48","author":"Paik, WH","year":"2014","journal-title":"J Clin Gastroenterol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.addr.2008.03.005","article-title":"Microbubbles in ultrasound-triggered drug and gene delivery","volume":"60","author":"Hernot, S","year":"2008","journal-title":"Adv Drug Deliv Rev"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1148\/radiol.10101079","article-title":"Tumor angiogenic marker expression levels during tumor growth: longitudinal assessment with molecularly targeted microbubbles and US imaging","volume":"258","author":"Deshpande, N","year":"2011","journal-title":"Radiology"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1148\/radiol.14140568","article-title":"Vascular endothelial growth factor receptor type 2-targeted contrast-enhanced US of pancreatic cancer neovasculature in a genetically engineered mouse model: potential for earlier detection","volume":"274","author":"Pysz, MA","year":"2015","journal-title":"Radiology"}],"container-title":["Gut and Liver"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pdf.medrang.co.kr\/ekjg\/ekjg009-06-06.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T20:31:31Z","timestamp":1567283491000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.gutnliver.org\/journal\/view.html?doi=10.5009\/gnl15077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,23]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11,23]]}},"alternative-id":["10.5009\/gnl15077"],"URL":"https:\/\/doi.org\/10.5009\/gnl15077","relation":{},"ISSN":["1976-2283","2005-1212"],"issn-type":[{"value":"1976-2283","type":"print"},{"value":"2005-1212","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,23]]}}}