{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T03:04:31Z","timestamp":1783998271739,"version":"3.55.0"},"reference-count":104,"publisher":"The Editorial Office of Gut and Liver","issue":"4","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["gutnliver.org"],"crossmark-restriction":true},"short-container-title":["Gut and Liver"],"published-print":{"date-parts":[[2026,7,15]]},"DOI":"10.5009\/gnl260015","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T01:12:02Z","timestamp":1782868322000},"page":"665-680","update-policy":"https:\/\/doi.org\/10.5009\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and Long-Term Outcomes of Direct-Acting Antivirals in Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis"],"prefix":"10.5009","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7802-0381","authenticated-orcid":false,"given":"Jeong-Ju","family":"Yoo","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8294-3517","authenticated-orcid":false,"given":"Seul Ki","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6862-1896","authenticated-orcid":false,"given":"Soon Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6588-9806","authenticated-orcid":false,"given":"Hyun","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Hepatology, Department of Internal Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3620-8175","authenticated-orcid":false,"given":"Eunju","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0783-509X","authenticated-orcid":false,"given":"Seong Hee","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7716-4850","authenticated-orcid":false,"given":"Young Eun","family":"Chon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Gastroenterology, CHA Bundang Hospital, CHA University, Seongnam, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0474-048X","authenticated-orcid":false,"given":"Eileen L.","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9350-1079","authenticated-orcid":false,"given":"Hyun Phil","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7884-1622","authenticated-orcid":false,"given":"Sangheun","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Hepatology, Department of Internal Medicine, International St. Mary\u2019s Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-3439","authenticated-orcid":false,"given":"Do Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7414-0258","authenticated-orcid":false,"given":"Gi Hyeon","family":"Seo","sequence":"additional","affiliation":[{"name":"VUNO Inc., Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1165-948X","authenticated-orcid":false,"given":"Hyung Joon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6958-3035","authenticated-orcid":false,"given":"Hyun Woong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2920","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.17998\/jlc.2024.03.13"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2024.0824"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.06.022"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2020.05.007"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.07.004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/v16121899"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.02.046"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14051505"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14092295"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12973"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.14309\/00000434-201710001-00931"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i13.1478"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2509059"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/lci2.13"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.09.023"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.05.045"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.06.015"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.01.020"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29126"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.02.027"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13456"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24790"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14256"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.07.007"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.08.008"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000923"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4739-z"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.5114\/ceh.2017.71483"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12854"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001082"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29855"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0194704"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14685"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14914"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001152"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.12727"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.09.029"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25352"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.10.038"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.03.040"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-019-09930-x"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12105"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2061"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.03.027"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-019-05641-3"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-026703"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.08.016"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1177\/2050640619841254"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2019.1847"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.07.040"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222605"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1412"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-019-07911-w"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-019-00870-9"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-53051-2"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2019.09.006"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz1160"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12010023"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2019.1956"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003115"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25744"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.3382-19"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2019.297"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2020.03.030"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2019.12.809"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0233212"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13547"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1002\/kjm2.12303"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v12.i9.628"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1159\/000510341"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001972"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-020-01747-y"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1097\/TXD.0000000000001049"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.14968"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.5114\/ceh.2021.104397"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2021.1951230"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13579"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13709"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000005070"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13627"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.12788\/fp.0165"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.1159\/000520721"},{"key":"ref83","unstructured":"Wu KC, Lee IC, Chi CT, et al. Comparable benefits of HCV eradication by direct acting antivirals and interferon-based therapy in patients with hepatocellular carcinoma undergoing surgical resection. Am J Cancer Res 2021;11:5526-5542."},{"key":"ref84","unstructured":"Tsai HY, Chang HP, Chen CJ, Hsu WL, Huang LY, Lee PC. Effects of direct-acting antiviral therapy for patients with advanced hepatocellular carcinoma and concomitant hepatitis C: a population-based cohort study. Eur Rev Med Pharmacol Sci 2021;25:7543-7552."},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58020259"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.13684"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.2010"},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v14.i6.1190"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.3390\/v14112316"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.3390\/v15010137"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.17998\/jlc.2022.05.24"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.16276"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17794"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17863"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1097\/JCMA.0000000000001051"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12725"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.04.017"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15598"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-323663"},{"key":"ref100","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S221187"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10020221"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.04.008"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.05.034"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1002\/cld.781"}],"container-title":["Gut and Liver"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pdf.medrang.co.kr\/GNL\/2026\/020\/GNL020-04-665.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/pdf.medrang.co.kr\/GNL\/2026\/020\/GNL020-04-665.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:19:19Z","timestamp":1783995559000},"score":1,"resource":{"primary":{"URL":"http:\/\/gutnliver.org\/journal\/view.html?doi=10.5009\/gnl260015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":104,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7,15]]}},"alternative-id":["10.5009\/gnl260015"],"URL":"https:\/\/doi.org\/10.5009\/gnl260015","relation":{},"ISSN":["1976-2283","2005-1212"],"issn-type":[{"value":"1976-2283","type":"print"},{"value":"2005-1212","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]},"assertion":[{"value":"http:\/\/gutnliver.org\/journal\/view.html?doi=10.5009\/gnl260015","URL":"http:\/\/gutnliver.org\/journal\/view.html?doi=10.5009\/gnl260015","name":"the_journal","label":"Gut and Liver","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2026-01-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-28","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-30","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-15","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026 The Editorial Office of Gut and Liver","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}