{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T13:04:51Z","timestamp":1785157491068,"version":"3.55.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Occupational Therapy"],"published-print":{"date-parts":[[1998,3]]},"abstract":"<jats:p>\n                    Objectives.\n                    <jats:italic toggle=\"yes\">Interrelationships between Rett syndrome scoliosis and symmetric and asymmetric motor pull, ambulation, and advancement of age were investigated in order to provide a treatment rationale for slowing the progression of scoliosis<\/jats:italic>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    Method.\n                    <jats:italic toggle=\"yes\">Questionnaires (<\/jats:italic>\n                    N =\n                    <jats:italic toggle=\"yes\">262) completed by International Rett Syndrome Association families were analyzed with logistic regression, odds ratio, Kruskal-Wallis one-way, and Fisher's exact test analyses<\/jats:italic>\n                    .\n                  <\/jats:p>\n                  <jats:p>\n                    Results.\n                    <jats:italic toggle=\"yes\">Rett syndrome scoliosis was found to be significantly related to orthopedic risk factors of asymmetric movements and positions (odds ratio =4.5,<\/jats:italic>\n                    p &lt;\n                    <jats:italic toggle=\"yes\">.001). The odds ratio for asymmetric upper body positioning (4.4), nonambulation (3.1), and age advancement (14.1) indicated that each was a significant predictor of scoliosis by logistic regression analysis. Univariate Kruskal-Wallis one-way analysis identified a significant relationship between scoliosis and asymmetric higher shoulder positioning (<\/jats:italic>\n                    p &lt;\n                    <jats:italic toggle=\"yes\">.001) and bodyside movements (<\/jats:italic>\n                    p =\n                    <jats:italic toggle=\"yes\">.03). Hemisyndrome aspects of Rett syndrome were identified as the increased prevalence of symptoms in either right or left bodyside.<\/jats:italic>\n                  <\/jats:p>\n                  <jats:p>\n                    Conclusion.\n                    <jats:italic toggle=\"yes\">A significant relationship was found between the prevalence of Rett syndrome scoliosis and orthopedic risk factors. These findings suggest a treatment approach for Rett syndrome scoliosis that focuses on balancing bilateral muscular pull<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.5014\/ajot.52.3.196","type":"journal-article","created":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T14:39:05Z","timestamp":1334587145000},"page":"196-204","source":"Crossref","is-referenced-by-count":7,"title":["The Relationship of Cumulative Motor Asymmetries to Scoliosis in Rett Syndrome"],"prefix":"10.1177","volume":"52","author":[{"given":"Marjorie K.","family":"McClure","sequence":"first","affiliation":[{"name":"Marjorie K. McClure, OTR\/L, is Occupational Therapist, The Medical Center, Beaver, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmela","family":"Battaglia","sequence":"additional","affiliation":[{"name":"Carmela Battaglia, MS, is Assistant Professor, Occupational Therapy Department, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"McClure","sequence":"additional","affiliation":[{"name":"Richard J. McClure, PhD, is Senior Research Principal, Neurophysics Laboratory, University of Pittsburgh Medical Center, 737 Parran Hall\/GSPH, 130 DeSoto Street, Pittsburgh, Pennsylvania 15213"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1998,3,1]]},"container-title":["American Journal of Occupational Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5014\/ajot.52.3.196","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/research.aota.org\/ajot\/article-pdf\/52\/3\/196\/60414\/196.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5014\/ajot.52.3.196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T12:34:11Z","timestamp":1785155651000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5014\/ajot.52.3.196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["10.5014\/ajot.52.3.196"],"URL":"https:\/\/doi.org\/10.5014\/ajot.52.3.196","relation":{},"ISSN":["1943-7676","1943-7676"],"issn-type":[{"value":"1943-7676","type":"print"},{"value":"1943-7676","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3]]}}}