{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:46:29Z","timestamp":1765295189994,"version":"3.40.5"},"reference-count":33,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2017R1C1B2005574"],"award-info":[{"award-number":["2017R1C1B2005574"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anndermatol.org"],"crossmark-restriction":false},"short-container-title":["Ann Dermatol"],"published-print":{"date-parts":[[2021]]},"DOI":"10.5021\/ad.2021.33.1.18","type":"journal-article","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T07:35:24Z","timestamp":1610523324000},"page":"18","update-policy":"https:\/\/doi.org\/10.5021\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["<i>PTEN<\/i> Promoter Hypermethylation Is Associated with Breslow Thickness in Acral Melanoma on the Heel, Forefoot, and Hallux"],"prefix":"10.5021","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8825-0877","authenticated-orcid":false,"given":"Hae Seok","family":"Park","sequence":"first","affiliation":[{"name":"Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3385-8180","authenticated-orcid":false,"given":"Jong Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9676-6681","authenticated-orcid":false,"given":"Mi Yeon","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3257-0297","authenticated-orcid":false,"given":"Kee Yang","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6285-2490","authenticated-orcid":false,"given":"Mi Ryung","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.5021\/ad.2021.33.1.18_ref1","doi-asserted-by":"crossref","first-page":"e120","DOI":"10.1371\/journal.pmed.0050120","volume":"5","author":"Viros","year":"2008","journal-title":"PLoS Med"},{"key":"10.5021\/ad.2021.33.1.18_ref2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nature22071","volume":"545","author":"Hayward","year":"2017","journal-title":"Nature"},{"key":"10.5021\/ad.2021.33.1.18_ref3","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/labinvest.2016.147","volume":"97","author":"Merkel","year":"2017","journal-title":"Lab Invest"},{"key":"10.5021\/ad.2021.33.1.18_ref4","doi-asserted-by":"crossref","first-page":"485","DOI":"10.5021\/ad.2014.26.4.485","volume":"26","author":"Jang","year":"2014","journal-title":"Ann Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref5","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1186\/s12885-016-2747-6","volume":"16","author":"Wang","year":"2016","journal-title":"BMC Cancer"},{"key":"10.5021\/ad.2021.33.1.18_ref6","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nature12477","volume":"500","author":"Alexandrov","year":"2013","journal-title":"Nature"},{"key":"10.5021\/ad.2021.33.1.18_ref7","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.jdermsci.2013.07.013","volume":"72","author":"Zebary","year":"2013","journal-title":"J Dermatol Sci"},{"key":"10.5021\/ad.2021.33.1.18_ref8","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/cup.12323","volume":"41","author":"Liau","year":"2014","journal-title":"J Cutan Pathol"},{"key":"10.5021\/ad.2021.33.1.18_ref9","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jid.2017.09.027","volume":"138","author":"Carrera","year":"2018","journal-title":"J Invest Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref10","first-page":"394","volume":"179","author":"de Unamuno Bustos","year":"2018","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref11","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/j.jid.2016.01.024","volume":"136","author":"Roh","year":"2016","journal-title":"J Invest Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref12","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1056\/NEJMc1512354","volume":"374","author":"Minagawa","year":"2016","journal-title":"N Engl J Med"},{"key":"10.5021\/ad.2021.33.1.18_ref13","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMc1706162","volume":"377","author":"Costello","year":"2017","journal-title":"N Engl J Med"},{"key":"10.5021\/ad.2021.33.1.18_ref14","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jaad.2018.07.064","volume":"80","author":"Rambhia","year":"2019","journal-title":"J Am Acad Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1346-8138.1980.tb01957.x","volume":"7","author":"Hosokawa","year":"1980","journal-title":"J Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1365-2133.1993.tb15138.x","volume":"128","author":"Dwyer","year":"1993","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref17","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1001\/jamadermatol.2013.5853","volume":"149","author":"Jung","year":"2013","journal-title":"JAMA Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref18","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jbiomech.2011.11.004","volume":"45","author":"Stucke","year":"2012","journal-title":"J Biomech"},{"key":"10.5021\/ad.2021.33.1.18_ref19","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1757-1146-6-42","volume":"6","author":"Galica","year":"2013","journal-title":"J Foot Ankle Res"},{"key":"10.5021\/ad.2021.33.1.18_ref20","doi-asserted-by":"crossref","first-page":"374","DOI":"10.5455\/aim.2014.22.374-378","volume":"22","author":"Skopljak","year":"2014","journal-title":"Acta Inform Med"},{"key":"10.5021\/ad.2021.33.1.18_ref21","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.4143\/crt.2017.535","volume":"50","author":"Lee","year":"2018","journal-title":"Cancer Res Treat"},{"key":"10.5021\/ad.2021.33.1.18_ref22","first-page":"134","volume":"7","author":"Roh","year":"2017","journal-title":"Am J Cancer Res"},{"key":"10.5021\/ad.2021.33.1.18_ref23","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/CMR.0000000000000222","volume":"26","author":"Vazquez Vde","year":"2016","journal-title":"Melanoma Res"},{"key":"10.5021\/ad.2021.33.1.18_ref24","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.det.2015.08.011","volume":"34","author":"Boer","year":"2016","journal-title":"Dermatol Clin"},{"key":"10.5021\/ad.2021.33.1.18_ref25","doi-asserted-by":"crossref","first-page":"5564","DOI":"10.1038\/s41598-017-05809-9","volume":"7","author":"Sheen","year":"2017","journal-title":"Sci Rep"},{"key":"10.5021\/ad.2021.33.1.18_ref26","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/00129334-200107000-00015","volume":"14","year":"2001","journal-title":"Adv Skin Wound Care"},{"key":"10.5021\/ad.2021.33.1.18_ref27","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1007\/s00421-017-3732-8","volume":"117","author":"Hodges","year":"2017","journal-title":"Eur J Appl Physiol"},{"key":"10.5021\/ad.2021.33.1.18_ref28","doi-asserted-by":"crossref","first-page":"32876","DOI":"10.18632\/oncotarget.8765","volume":"7","author":"Liu","year":"2016","journal-title":"Oncotarget"},{"key":"10.5021\/ad.2021.33.1.18_ref29","doi-asserted-by":"crossref","first-page":"5153","DOI":"10.1158\/1078-0432.CCR-05-0397","volume":"11","author":"Mikhail","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.5021\/ad.2021.33.1.18_ref30","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/S0002-9440(10)64627-5","volume":"157","author":"Zhou","year":"2000","journal-title":"Am J Pathol"},{"key":"10.5021\/ad.2021.33.1.18_ref31","doi-asserted-by":"crossref","first-page":"5527","DOI":"10.1158\/1078-0432.CCR-14-1027","volume":"20","author":"Bucheit","year":"2014","journal-title":"Clin Cancer Res"},{"key":"10.5021\/ad.2021.33.1.18_ref32","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.jid.2018.07.031","volume":"139","author":"Giles","year":"2019","journal-title":"J Invest Dermatol"},{"key":"10.5021\/ad.2021.33.1.18_ref33","doi-asserted-by":"crossref","first-page":"5379","DOI":"10.1158\/1078-0432.CCR-13-2661","volume":"20","author":"Hopkins","year":"2014","journal-title":"Clin Cancer Res"}],"container-title":["Annals of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/anndermatol.org\/pdf\/10.5021\/ad.2021.33.1.18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.2021.33.1.18","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.2021.33.1.18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T23:41:55Z","timestamp":1610581315000},"score":1,"resource":{"primary":{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.2021.33.1.18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.5021\/ad.2021.33.1.18","relation":{},"ISSN":["1013-9087","2005-3894"],"issn-type":[{"type":"print","value":"1013-9087"},{"type":"electronic","value":"2005-3894"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"2019-09-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-13","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-30","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2021 The Korean Dermatological Association and The Korean Society for Investigative Dermatology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}