{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T06:47:34Z","timestamp":1776235654417,"version":"3.50.1"},"reference-count":40,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100014717","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103760"],"award-info":[{"award-number":["82103760"]}],"id":[{"id":"10.13039\/100014717","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["anndermatol.org"],"crossmark-restriction":false},"short-container-title":["Ann Dermatol"],"published-print":{"date-parts":[[2023]]},"DOI":"10.5021\/ad.22.126","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T02:48:30Z","timestamp":1675046910000},"page":"46","update-policy":"https:\/\/doi.org\/10.5021\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata"],"prefix":"10.5021","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7377-7000","authenticated-orcid":false,"given":"Si-si","family":"Qi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4371-2617","authenticated-orcid":false,"given":"Ying","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8312-9018","authenticated-orcid":false,"given":"You-yu","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0523-1778","authenticated-orcid":false,"given":"Rui-ming","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7322-0803","authenticated-orcid":false,"given":"Jun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1328-9769","authenticated-orcid":false,"given":"Qin-ping","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.5021\/ad.22.126_ref1","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1038\/jid.2010.260","volume":"130","author":"Gilhar","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.5021\/ad.22.126_ref2","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1111\/1346-8138.12976","volume":"42","author":"Tan","year":"2015","journal-title":"J Dermatol"},{"key":"10.5021\/ad.22.126_ref3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/13548506.2014.894641","volume":"20","author":"Qi","year":"2015","journal-title":"Psychol Health Med"},{"key":"10.5021\/ad.22.126_ref4","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1111\/j.1365-2133.2012.10955.x","volume":"166","author":"Messenger","year":"2012","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.22.126_ref5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00109-013-1043-z","volume":"91","author":"Zhu","year":"2013","journal-title":"J Mol Med (Berl)"},{"key":"10.5021\/ad.22.126_ref6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.canlet.2019.04.015","volume":"454","author":"Wang","year":"2019","journal-title":"Cancer Lett"},{"key":"10.5021\/ad.22.126_ref7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/intimm\/dxx019","volume":"29","author":"Park","year":"2017","journal-title":"Int Immunol"},{"key":"10.5021\/ad.22.126_ref8","doi-asserted-by":"crossref","first-page":"61","DOI":"10.5021\/ad.2012.24.1.61","volume":"24","author":"Lew","year":"2012","journal-title":"Ann Dermatol"},{"key":"10.5021\/ad.22.126_ref9","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1111\/1346-8138.12978","volume":"42","author":"Han","year":"2015","journal-title":"J Dermatol"},{"key":"10.5021\/ad.22.126_ref10","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1159\/000350933","volume":"226","author":"Tanemura","year":"2013","journal-title":"Dermatology"},{"key":"10.5021\/ad.22.126_ref11","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/jdv.14775","volume":"32","author":"Loh","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.5021\/ad.22.126_ref12","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1111\/ijd.12808","volume":"55","author":"Atwa","year":"2016","journal-title":"Int J Dermatol"},{"key":"10.5021\/ad.22.126_ref13","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/ijd.12994","volume":"55","author":"El-Morsy","year":"2016","journal-title":"Int J Dermatol"},{"key":"10.5021\/ad.22.126_ref14","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/jocd.12664","volume":"17","author":"Morsy","year":"2018","journal-title":"J Cosmet Dermatol"},{"key":"10.5021\/ad.22.126_ref15","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/bjd.13469","volume":"172","author":"Langley","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.22.126_ref16","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jaci.2015.11.001","volume":"137","author":"Guttman-Yassky","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"10.5021\/ad.22.126_ref17","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1111\/pde.13699","volume":"36","author":"Aleisa","year":"2019","journal-title":"Pediatr Dermatol"},{"key":"10.5021\/ad.22.126_ref18","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s00403-018-1853-5","volume":"310","author":"Guttman-Yassky","year":"2018","journal-title":"Arch Dermatol Res"},{"key":"10.5021\/ad.22.126_ref19","doi-asserted-by":"crossref","first-page":"14421","DOI":"10.1002\/jcb.28700","volume":"120","author":"Sheng","year":"2019","journal-title":"J Cell Biochem"},{"key":"10.5021\/ad.22.126_ref20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10147-019-01532-9","volume":"25","author":"Shi","year":"2020","journal-title":"Int J Clin Oncol"},{"key":"10.5021\/ad.22.126_ref21","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.7150\/jca.38048","volume":"11","author":"Wei","year":"2020","journal-title":"J Cancer"},{"key":"10.5021\/ad.22.126_ref22","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.jfma.2019.02.014","volume":"118","author":"Liu","year":"2019","journal-title":"J Formos Med Assoc"},{"key":"10.5021\/ad.22.126_ref23","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.4143\/crt.2018.638","volume":"51","author":"Yang","year":"2019","journal-title":"Cancer Res Treat"},{"key":"10.5021\/ad.22.126_ref24","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.4161\/cc.20809","volume":"11","author":"Liao","year":"2012","journal-title":"Cell Cycle"},{"key":"10.5021\/ad.22.126_ref25","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/embor.2011.98","volume":"12","author":"Zhang","year":"2011","journal-title":"EMBO Rep"},{"key":"10.5021\/ad.22.126_ref26","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1002\/iub.2147","volume":"71","author":"Xie","year":"2019","journal-title":"IUBMB Life"},{"key":"10.5021\/ad.22.126_ref27","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/s41467-018-03224-w","volume":"9","author":"Cooks","year":"2018","journal-title":"Nat Commun"},{"key":"10.5021\/ad.22.126_ref28","doi-asserted-by":"crossref","first-page":"52762","DOI":"10.1074\/jbc.M405764200","volume":"279","author":"Liu","year":"2004","journal-title":"J Biol Chem"},{"key":"10.5021\/ad.22.126_ref29","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1002\/eji.201445150","volume":"45","author":"Reppert","year":"2015","journal-title":"Eur J Immunol"},{"key":"10.5021\/ad.22.126_ref30","first-page":"176","volume":"2","author":"Al-Daraji","year":"2009","journal-title":"Int J Clin Exp Med"},{"key":"10.5021\/ad.22.126_ref31","doi-asserted-by":"crossref","first-page":"11724","DOI":"10.1038\/ncomms11724","volume":"7","author":"Alrefai","year":"2016","journal-title":"Nat Commun"},{"key":"10.5021\/ad.22.126_ref32","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cell.2013.08.057","volume":"155","author":"Wilson","year":"2013","journal-title":"Cell"},{"key":"10.5021\/ad.22.126_ref33","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.clim.2006.01.001","volume":"119","author":"Fujii","year":"2006","journal-title":"Clin Immunol"},{"key":"10.5021\/ad.22.126_ref34","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s13148-015-0063-7","volume":"7","author":"Luo","year":"2015","journal-title":"Clin Epigenetics"},{"key":"10.5021\/ad.22.126_ref35","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.immuni.2009.07.009","volume":"31","author":"Gomez-Rodriguez","year":"2009","journal-title":"Immunity"},{"key":"10.5021\/ad.22.126_ref36","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1111\/cea.12493","volume":"45","author":"Koch","year":"2015","journal-title":"Clin Exp Allergy"},{"key":"10.5021\/ad.22.126_ref37","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/imm.12994","volume":"155","author":"Liu","year":"2018","journal-title":"Immunology"},{"key":"10.5021\/ad.22.126_ref38","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1111\/apa.15789","volume":"110","author":"Li","year":"2021","journal-title":"Acta Paediatr"},{"key":"10.5021\/ad.22.126_ref39","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/gene.2013.69","volume":"15","author":"Smigielska-Czepiel","year":"2014","journal-title":"Genes Immun"},{"key":"10.5021\/ad.22.126_ref40","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.3892\/ijo.2015.2941","volume":"46","author":"Fujita","year":"2015","journal-title":"Int J Oncol"}],"container-title":["Annals of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/anndermatol.org\/pdf\/10.5021\/ad.22.126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.22.126","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.22.126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T02:39:53Z","timestamp":1675305593000},"score":1,"resource":{"primary":{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.22.126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.5021\/ad.22.126","relation":{},"ISSN":["1013-9087","2005-3894"],"issn-type":[{"value":"1013-9087","type":"print"},{"value":"2005-3894","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"2022-07-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-29","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-20","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 The Korean Dermatological Association and The Korean Society for Investigative Dermatology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}