{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:58:11Z","timestamp":1785394691869,"version":"3.55.0"},"reference-count":31,"publisher":"XMLink","issue":"4","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["anndermatol.org"],"crossmark-restriction":false},"short-container-title":["Ann Dermatol"],"published-print":{"date-parts":[[2026]]},"DOI":"10.5021\/ad.25.222","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:16:52Z","timestamp":1778818612000},"page":"320","update-policy":"https:\/\/doi.org\/10.5021\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and Safety of Alitretinoin for Chronic Hand Eczema: A Meta-Analysis"],"prefix":"10.5021","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0677-4560","authenticated-orcid":false,"given":"Yu Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6143-2462","authenticated-orcid":false,"given":"Jung Min","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1118-9113","authenticated-orcid":false,"given":"Yun Jeong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-9635","authenticated-orcid":false,"given":"Tae Young","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1215-7078","authenticated-orcid":false,"given":"Jae Eun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1066-5765","authenticated-orcid":false,"given":"Byeol","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0320-8088","authenticated-orcid":false,"given":"Jung-Soo","family":"Pyo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3133-0478","authenticated-orcid":false,"given":"June Hyunkyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","reference":[{"key":"10.5021\/ad.25.222_ref1","doi-asserted-by":"crossref","first-page":"4198","DOI":"10.3390\/jcm12134198","volume":"12","author":"Zalewski","year":"2023","journal-title":"J Clin Med"},{"key":"10.5021\/ad.25.222_ref2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5021\/ad.2021.33.1.46","volume":"33","author":"Seol","year":"2021","journal-title":"Ann Dermatol"},{"key":"10.5021\/ad.25.222_ref3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.2340\/00015555-1256","volume":"92","author":"Diepgen","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"10.5021\/ad.25.222_ref4","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/j.1365-2133.2008.08487.x","volume":"158","author":"Ruzicka","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.25.222_ref5","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1001\/archderm.140.12.1453","volume":"140","author":"Ruzicka","year":"2004","journal-title":"Arch Dermatol"},{"key":"10.5021\/ad.25.222_ref6","first-page":"70","volume":"12","author":"Al-Dhubaibi","year":"2018","journal-title":"Int J Health Sci (Qassim)"},{"key":"10.5021\/ad.25.222_ref7","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1600-0536.2007.01179.x","volume":"57","author":"Diepgen","year":"2007","journal-title":"Contact Dermat"},{"issue":"Suppl 3","key":"10.5021\/ad.25.222_ref8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1468-3083.2010.03615.x","volume":"24","author":"Bissonnette","year":"2010","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.5021\/ad.25.222_ref9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1600-0536.2008.01362.x","volume":"59","author":"Agner","year":"2008","journal-title":"Contact Dermat"},{"key":"10.5021\/ad.25.222_ref10","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1111\/1346-8138.15071","volume":"46","author":"Cheon","year":"2019","journal-title":"J Dermatol"},{"key":"10.5021\/ad.25.222_ref11","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1177\/12034754211071123","volume":"26","author":"Bednar","year":"2022","journal-title":"J Cutan Med Surg"},{"key":"10.5021\/ad.25.222_ref12","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/09546634.2016.1227422","volume":"27","author":"Tha\u00e7i","year":"2016","journal-title":"J Dermatolog Treat"},{"key":"10.5021\/ad.25.222_ref13","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2230.2010.03955.x","volume":"36","author":"Dirschka","year":"2011","journal-title":"Clin Exp Dermatol"},{"key":"10.5021\/ad.25.222_ref14","doi-asserted-by":"crossref","first-page":"595","DOI":"10.5021\/ad.2019.31.6.595","volume":"31","author":"Jo","year":"2019","journal-title":"Ann Dermatol"},{"key":"10.5021\/ad.25.222_ref15","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/jdv.16088","volume":"34","author":"Luchsinger","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.5021\/ad.25.222_ref16","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/j.1365-2230.2012.04396.x","volume":"37","author":"Lynde","year":"2012","journal-title":"Clin Exp Dermatol"},{"key":"10.5021\/ad.25.222_ref17","first-page":"1261","volume":"14","author":"Augustin","year":"2016","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.5021\/ad.25.222_ref18","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1365-2133.2009.09572.x","volume":"162","author":"Bissonnette","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.5021\/ad.25.222_ref19","doi-asserted-by":"crossref","first-page":"e14911","DOI":"10.1111\/dth.14911","volume":"34","author":"Ferrucci","year":"2021","journal-title":"Dermatol Ther"},{"key":"10.5021\/ad.25.222_ref20","first-page":"1198","volume":"13","author":"Fowler","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"10.5021\/ad.25.222_ref21","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1097\/DER.0b013e3182987773","volume":"24","author":"Gola","year":"2013","journal-title":"Dermatitis"},{"key":"10.5021\/ad.25.222_ref22","first-page":"435","volume":"149","author":"Gola","year":"2014","journal-title":"G Ital Dermatol Venereol"},{"key":"10.5021\/ad.25.222_ref23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1684\/ejd.2018.3484","volume":"29","author":"Halioua","year":"2019","journal-title":"Eur J Dermatol"},{"key":"10.5021\/ad.25.222_ref24","doi-asserted-by":"crossref","first-page":"332","DOI":"10.2310\/7750.2014.13195","volume":"18","author":"Ham","year":"2014","journal-title":"J Cutan Med Surg"},{"key":"10.5021\/ad.25.222_ref25","first-page":"adv00043","volume":"100","author":"Jang","year":"2020","journal-title":"Acta Derm Venereol"},{"key":"10.5021\/ad.25.222_ref26","doi-asserted-by":"crossref","first-page":"e12980","DOI":"10.1111\/dth.12980","volume":"32","author":"Kim","year":"2019","journal-title":"Dermatol Ther"},{"key":"10.5021\/ad.25.222_ref27","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1684\/ejd.2011.1396","volume":"21","author":"Kubica","year":"2011","journal-title":"Eur J Dermatol"},{"key":"10.5021\/ad.25.222_ref28","doi-asserted-by":"crossref","first-page":"364","DOI":"10.5021\/ad.2016.28.3.364","volume":"28","author":"Kwon","year":"2016","journal-title":"Ann Dermatol"},{"key":"10.5021\/ad.25.222_ref29","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/dth.12362","volume":"29","author":"Politiek","year":"2016","journal-title":"Dermatol Ther"},{"issue":"Suppl 2","key":"10.5021\/ad.25.222_ref30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1365-2230.2011.04035.x","volume":"36","author":"Schmitt-Hoffmann","year":"2011","journal-title":"Clin Exp Dermatol"},{"key":"10.5021\/ad.25.222_ref31","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/cod.14161","volume":"87","author":"Voorberg","year":"2022","journal-title":"Contact Dermat"}],"container-title":["Annals of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/anndermatol.org\/pdf\/10.5021\/ad.25.222","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.25.222","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.25.222","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:01:01Z","timestamp":1785391261000},"score":1,"resource":{"primary":{"URL":"https:\/\/anndermatol.org\/DOIx.php?id=10.5021\/ad.25.222"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5021\/ad.25.222","relation":{},"ISSN":["1013-9087","2005-3894"],"issn-type":[{"value":"1013-9087","type":"print"},{"value":"2005-3894","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"2025-11-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-16","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-21","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2026 The Korean Dermatological Association and The Korean Society for Investigative Dermatology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}