{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:24:01Z","timestamp":1771467841063,"version":"3.50.1"},"reference-count":27,"publisher":"Rambam Health Corporation","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rambam Maimonides Med J"],"abstract":"<jats:p>Objectives: This study aims to investigate the efficacy and outcomes of transurethral resection of the prostate (TURP) in the context of younger male patients.  Methods: Males aged \u226455 who underwent TURP at Rambam Health Care Campus from January 2011 to August 2023 were retrospectively reviewed. Clinicodemographic characteristics, indications for surgery, uroflowmetry, pressure-flow study, and early and late postoperative outcomes were collected. Patients with urethral or bladder abnormalities were excluded. Chi-square and Fisher\u2019s exact tests were employed for bivariate analysis.  Results: Inclusion criteria were met by 58 men who underwent TURP at a median age of 52 years (interquartile range [IQR] 49.5\u201354). Median prostate size was 35 mL (24.5\u201356), with median prostate-specific antigen of 1.4 ng\/mL (0.65\u20133.1). A total of 60% of patients used \u03b1-blockers, and 19% used 5\u03b1-reductase inhibitors pre-surgery. Overall, 54 (93.1%) had severe lower urinary tract symptoms (LUTS), with 34 (59%) being predominantly emptying and 20 (35%) storage. Most surgeries were performed for refractory LUTS in 38 (66%), followed by urinary retention in 16 (28%). At 6 weeks, 57 (98%) patients were catheter-free. The maximum flow rate and residual volume showed significant improvement from 9 mL\/s to 21 mL\/s (P=0.01), and from 171 mL to 61 mL (P=0.006), respectively. Pathology revealed benign prostatic hyperplasia in 53 (91.4%), and inflammation in 5 (8.5%). A total of 13 auxiliary procedures were required in 12 patients (20.7%) during follow-up: 7 transurethral bladder neck incisions, 3 re-TURP, 1 meatus widening, and 1 patient required artificial urinary sphincter implantation followed by simple cystectomy for end-stage bladder.  Conclusions: In young men, TURP showed short-term gains in flowmetry and catheter removal rates, but a sustained need for subsequent procedures in the long run. In this unique population, patients should be carefully selected, and alternative, less aggressive, interventions should be considered.<\/jats:p>","DOI":"10.5041\/rmmj.10520","type":"journal-article","created":{"date-parts":[[2024,4,28]],"date-time":"2024-04-28T06:11:15Z","timestamp":1714284675000},"page":"e0006","source":"Crossref","is-referenced-by-count":1,"title":["Transurethral Resection of the Prostate in Younger Men: Effectiveness and Long-term Outcomes"],"prefix":"10.5041","volume":"15","author":[{"name":"Department of Urology, Rambam Health Care Campus, Haifa, Israel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamil","family":"Malshy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Warren Alpert Medical School of Brown University, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etan","family":"Eigner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Urology, Rambam Health Care Campus, Haifa, Israel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Ochsner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Warren Alpert Medical School of Brown University, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Warren Alpert Medical School of Brown University, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Nsair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Urology, Rambam Health Care Campus, Haifa, Israel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borivoj","family":"Golijanin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Minimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Warren Alpert Medical School of Brown University, Providence, RI, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Mullerad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Urology, Rambam Health Care Campus, Haifa, Israel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2983","published-online":{"date-parts":[[2024,4,28]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"7984","DOI":"10.1038\/s41598-017-06628-8","article-title":"The global burden of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a systematic review and meta-analysis","volume":"7","author":"Lee","year":"2017","unstructured":"1. 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Int J Surg Case Rep 2022;93:107021.","journal-title":"Int J Surg Case Rep"}],"container-title":["Rambam Maimonides Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.rmmj.org.il\/userimages\/1804\/2\/PublishFiles\/1843Article.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T11:25:25Z","timestamp":1724585125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.rmmj.org.il\/issues\/62\/articles\/1843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,28]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,4,28]]}},"URL":"https:\/\/doi.org\/10.5041\/rmmj.10520","relation":{},"ISSN":["2076-9172"],"issn-type":[{"value":"2076-9172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,28]]}}}