{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:03:55Z","timestamp":1777633435607,"version":"3.51.4"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,6,30]],"date-time":"2019-06-30T00:00:00Z","timestamp":1561852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["www.bloodresearch.or.kr"],"crossmark-restriction":true},"short-container-title":["Blood Res"],"published-print":{"date-parts":[[2019,6,30]]},"DOI":"10.5045\/br.2019.54.2.120","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T20:52:03Z","timestamp":1562273523000},"page":"120-124","update-policy":"https:\/\/doi.org\/10.5045\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Determining the risk factors associated with the development of\n                    <i>Clostridium difficile<\/i>\n                    infection in patients with hematological diseases"],"prefix":"10.1007","volume":"54","author":[{"given":"Yu Ling","family":"Lee-Tsai","sequence":"first","affiliation":[{"name":"Department of Hematology and Oncology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Luna-Santiago","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Demichelis-G\u00f3mez","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Ponce-de-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Infectology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Ochoa-Hein","sequence":"additional","affiliation":[{"name":"Departament of Hospital Epidemiology and Quality Control of Medical Care, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla Mar\u00eda","family":"Tamez-Torres","sequence":"additional","affiliation":[{"name":"Department of Infectology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda T","family":"Bourlon","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christianne","family":"Bourlon","sequence":"additional","affiliation":[{"name":"Department of Hematology and Oncology, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"10.5045\/br.2019.54.2.120_ref1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1038\/nrgastro.2016.25","volume":"13","author":"Martin","year":"2016","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.5045\/br.2019.54.2.120_ref2","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/ajg.2013.4","volume":"108","author":"Surawicz","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.5045\/br.2019.54.2.120_ref3","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/S1995-7645(14)60197-8","volume":"7S1","author":"Khan","year":"2014","journal-title":"Asian Pac J Trop Med"},{"key":"10.5045\/br.2019.54.2.120_ref4","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3109\/1040841X.2011.556598","volume":"37","author":"Kachrimanidou","year":"2011","journal-title":"Crit Rev Microbiol"},{"key":"10.5045\/br.2019.54.2.120_ref5","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bjid.2014.07.004","volume":"19","author":"Lopardo","year":"2015","journal-title":"Braz J Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref6","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.bjid.2017.05.007","volume":"21","author":"D\u00e1vila","year":"2017","journal-title":"Braz J Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref7","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.cgh.2013.03.016","volume":"11","author":"Dupont","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.5045\/br.2019.54.2.120_ref8","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1086\/523582","volume":"45","author":"Dubberke","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref9","first-page":"371","volume":"61","author":"Camacho-Ortiz","year":"2009","journal-title":"Rev Invest Clin"},{"key":"10.5045\/br.2019.54.2.120_ref10","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1086\/651706","volume":"31","author":"Cohen","year":"2010","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.5045\/br.2019.54.2.120_ref11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/clinids\/17.1.109","volume":"17","author":"Anand","year":"1993","journal-title":"Clin Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref12","doi-asserted-by":"crossref","first-page":"4442","DOI":"10.2174\/0929867323666161028162018","volume":"23","author":"Peretz","year":"2016","journal-title":"Curr Med Chem"},{"key":"10.5045\/br.2019.54.2.120_ref13","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1099\/jmm.0.000028","volume":"64","author":"Gu","year":"2015","journal-title":"J Med Microbiol"},{"key":"10.5045\/br.2019.54.2.120_ref14","doi-asserted-by":"crossref","first-page":"6602","DOI":"10.3748\/wjg.v20.i21.6602","volume":"20","author":"Gweon","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.5045\/br.2019.54.2.120_ref15","doi-asserted-by":"crossref","first-page":"e0157839","DOI":"10.1371\/journal.pone.0157839","volume":"11","author":"Selvey","year":"2016","journal-title":"PLoS One"},{"key":"10.5045\/br.2019.54.2.120_ref16","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1177\/1078155213490004","volume":"20","author":"Parmar","year":"2014","journal-title":"J Oncol Pharm Pract"},{"key":"10.5045\/br.2019.54.2.120_ref17","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1086\/338721","volume":"34","author":"Altclas","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref18","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00277-009-0772-0","volume":"89","author":"Schalk","year":"2010","journal-title":"Ann Hematol"},{"key":"10.5045\/br.2019.54.2.120_ref19","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1590\/S0036-46652014000400010","volume":"56","author":"Spad\u00e3o","year":"2014","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.5045\/br.2019.54.2.120_ref20","volume-title":"WHO classification of tumours of haematopoietic and lymphoid tissues","author":"Swerdlow","year":"2017","edition":"Revised 4th ed"},{"key":"10.5045\/br.2019.54.2.120_ref21","unstructured":"National Institutes of Health. Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0. Bethesda, MD. National Institutes of Health. 2017. Accessed September 18, 2018.  https:\/\/ctep.cancer.gov\/protocolDevelopment\/electronic_applications\/docs\/CTCAE_v5_Quick_Reference_8.5x11.pdf"},{"key":"10.5045\/br.2019.54.2.120_ref22","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/cid\/cix669","volume":"65","author":"Shane","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref23","first-page":"eP187","author":"Eckert","year":"2013","journal-title":"ECCMID (Annual Congress Abstracts)"},{"key":"10.5045\/br.2019.54.2.120_ref24","unstructured":"CM0601. Clostridium difficile agar base. Basingstoke, UK. Thermo Fisher Scientific Inc. 2013. Accessed September 18, 2018.  http:\/\/www.oxoid.com\/UK\/blue\/prod_detail\/prod_detail.asp?pr=CM0601&org=52&c=UK&lang=EN"},{"key":"10.5045\/br.2019.54.2.120_ref25","unstructured":"Xpert\u00ae C. difficile\/Epi. 45-minute detection & differentiation of clostridium difficile & the Epidemic 027 strain. Sunnyvale, CA. Cepheid. 2018. Accessed September 18, 2018.  http:\/\/www.cepheid.com\/us\/cepheid-solutions\/clinical-ivd-tests\/healthcare-associated-infections\/xpert-c-difficile-epi"},{"key":"10.5045\/br.2019.54.2.120_ref26","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1086\/322616","volume":"33","author":"Gorschl\u00fcter","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref27","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1093\/infdis\/166.3.561","volume":"166","author":"Clabots","year":"1992","journal-title":"J Infect Dis"},{"key":"10.5045\/br.2019.54.2.120_ref28","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.ejon.2010.11.002","volume":"15","author":"Apostolopoulou","year":"2011","journal-title":"Eur J Oncol Nurs"},{"key":"10.5045\/br.2019.54.2.120_ref29","doi-asserted-by":"crossref","first-page":"31498","DOI":"10.1038\/srep31498","volume":"6","author":"Fuereder","year":"2016","journal-title":"Sci Rep"},{"key":"10.5045\/br.2019.54.2.120_ref30","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1007\/s00520-014-2174-7","volume":"22","author":"Yoon","year":"2014","journal-title":"Support Care Cancer"},{"key":"10.5045\/br.2019.54.2.120_ref31","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cix1085","volume":"66","author":"McDonald","year":"2018","journal-title":"Clin Infect Dis"}],"container-title":["BLOOD RESEARCH"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.5045\/br.2019.54.2.120","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5045\/br.2019.54.2.120","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/pdf.medrang.co.kr\/BR\/2019\/054\/br-54-120.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5045\/br.2019.54.2.120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T22:26:56Z","timestamp":1773354416000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.bloodresearch.or.kr\/journal\/view.html?doi=10.5045\/br.2019.54.2.120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,30]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,6,30]]}},"alternative-id":["10.5045\/br.2019.54.2.120"],"URL":"https:\/\/doi.org\/10.5045\/br.2019.54.2.120","relation":{},"ISSN":["2287-979X","2288-0011"],"issn-type":[{"value":"2287-979X","type":"print"},{"value":"2288-0011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,30]]},"assertion":[{"value":"http:\/\/www.bloodresearch.or.kr\/journal\/view.html?doi=10.5045\/br.2019.54.2.120","URL":"http:\/\/www.bloodresearch.or.kr\/journal\/view.html?doi=10.5045\/br.2019.54.2.120","name":"the_journal","label":"Blood Res","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2018-12-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-26","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2019 The Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}