{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:32:28Z","timestamp":1778873548987,"version":"3.51.4"},"reference-count":21,"publisher":"XMLink","issue":"5","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100009624","name":"Yonsei University College of Dentistry","doi-asserted-by":"publisher","award":["6-2014-0084"],"award-info":[{"award-number":["6-2014-0084"]}],"id":[{"id":"10.13039\/501100009624","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Periodontal Implant Sci"],"published-print":{"date-parts":[[2016]]},"DOI":"10.5051\/jpis.2016.46.5.350","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T02:47:33Z","timestamp":1477536453000},"page":"350","update-policy":"https:\/\/doi.org\/10.5051\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Increased osteoinductivity and mineralization by minimal concentration of bone morphogenetic protein-2 loaded onto biphasic calcium phosphate in a rabbit sinus"],"prefix":"10.5051","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2238-2965","authenticated-orcid":false,"given":"Jae-Shin","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-7209","authenticated-orcid":false,"given":"Jae-Kook","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1276-5978","authenticated-orcid":false,"given":"Jung-Seok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6704-6124","authenticated-orcid":false,"given":"Seong-Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6777-5287","authenticated-orcid":false,"given":"Kyoo-Sung","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","reference":[{"key":"10.5051\/jpis.2016.46.5.350_ref1","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1111\/cid.12223","volume":"17","author":"Kim","year":"2015","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref2","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1023\/A:1022872421333","volume":"14","author":"LeGeros","year":"2003","journal-title":"J Mater Sci Mater Med"},{"key":"10.5051\/jpis.2016.46.5.350_ref3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.11607\/jomi.3709","volume":"30","author":"Lim","year":"2015","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.5051\/jpis.2016.46.5.350_ref4","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1111\/cid.12145","volume":"17","author":"Mangano","year":"2015","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref5","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1089\/ten.tea.2012.0724","volume":"19","author":"Choi","year":"2013","journal-title":"Tissue Eng Part A"},{"key":"10.5051\/jpis.2016.46.5.350_ref6","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1034\/j.1600-0501.2002.130409.x","volume":"13","author":"Asai","year":"2002","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref7","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/1521-4036(200010)42:6<663::AID-BIMJ663>3.0.CO;2-7","volume":"42","author":"Brunner","year":"2000","journal-title":"Biom J"},{"key":"10.5051\/jpis.2016.46.5.350_ref8","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/cid.12354","volume":"18","author":"Torrecillas-Mart\u00ednez","year":"2016","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref9","author":"Hong","year":"2015","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref10","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1097\/00007632-200212010-00005","volume":"27","author":"Boden","year":"2002","journal-title":"Spine"},{"key":"10.5051\/jpis.2016.46.5.350_ref11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/jcpe.12329","volume":"42","author":"Yon","year":"2015","journal-title":"J Clin Periodontol"},{"key":"10.5051\/jpis.2016.46.5.350_ref12","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.joms.2014.03.027","volume":"72","author":"Kim","year":"2014","journal-title":"J Oral Maxillofac Surg"},{"key":"10.5051\/jpis.2016.46.5.350_ref13","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1023\/A:1018902720816","volume":"10","author":"Kenley","year":"1993","journal-title":"Pharm Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref14","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1007\/s10529-009-0100-8","volume":"31","author":"Haidar","year":"2009","journal-title":"Biotechnol Lett"},{"key":"10.5051\/jpis.2016.46.5.350_ref15","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1600-0501.2007.01431.x","volume":"19","author":"Jung","year":"2008","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref16","doi-asserted-by":"crossref","first-page":"3304","DOI":"10.1002\/jbm.a.34278","volume":"100","author":"Kim","year":"2012","journal-title":"J Biomed Mater Res A"},{"key":"10.5051\/jpis.2016.46.5.350_ref17","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.tripleo.2011.04.013","volume":"113","author":"Jang","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.5051\/jpis.2016.46.5.350_ref18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.5051\/jpis.2016.46.1.57","volume":"46","author":"Lim","year":"2016","journal-title":"J Periodontal Implant Sci"},{"key":"10.5051\/jpis.2016.46.5.350_ref19","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1111\/clr.12471","volume":"26","author":"Kim","year":"2015","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref20","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1111\/j.1600-0765.2012.01477.x","volume":"47","author":"Park","year":"2012","journal-title":"J Periodontal Res"},{"key":"10.5051\/jpis.2016.46.5.350_ref21","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1600-0501.2011.02222.x","volume":"23","author":"Choi","year":"2012","journal-title":"Clin Oral Implants Res"}],"container-title":["Journal of Periodontal &amp; Implant Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/synapse.koreamed.org\/pdf\/10.5051\/jpis.2016.46.5.350","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:14:49Z","timestamp":1589526889000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.5051\/jpis.2016.46.5.350","relation":{},"ISSN":["2093-2278","2093-2286"],"issn-type":[{"value":"2093-2278","type":"print"},{"value":"2093-2286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"http:\/\/www.jpis.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","URL":"http:\/\/www.jpis.org\/DOIx.php?id=10.5051\/jpis.2016.46.5.350","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2016-07-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-20","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2016 Korean Academy of Periodontology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/).","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}