{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T17:48:15Z","timestamp":1780681695794,"version":"3.54.1"},"reference-count":30,"publisher":"XMLink","issue":"2","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI15C1535"],"award-info":[{"award-number":["HI15C1535"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["synapse.koreamed.org"],"crossmark-restriction":false},"short-container-title":["J Periodontal Implant Sci"],"DOI":"10.5051\/jpis.2019.49.2.114","type":"journal-article","created":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T06:36:07Z","timestamp":1556606167000},"page":"114","update-policy":"https:\/\/doi.org\/10.5051\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Improvement of the osteogenic potential of ErhBMP-2-\/EGCG-coated biphasic calcium phosphate bone substitute: <i>in vitro<\/i> and <i>in vivo<\/i> activity"],"prefix":"10.5051","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8349-316X","authenticated-orcid":false,"given":"Jae-ho","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7250-721X","authenticated-orcid":false,"given":"Seunghan","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Dental Biomaterials, Institute of Biomaterials-Implant, Wonkwang University School of Dentistry, Iksan, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6361-4104","authenticated-orcid":false,"given":"Sungtae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2019]]},"reference":[{"key":"10.5051\/jpis.2019.49.2.114_ref1","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1054\/bjom.2000.0533","volume":"38","author":"Bessho","year":"2000","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.5051\/jpis.2019.49.2.114_ref2","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.1016\/j.biomaterials.2010.01.075","volume":"31","author":"Lee","year":"2010","journal-title":"Biomaterials"},{"key":"10.5051\/jpis.2019.49.2.114_ref3","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.pep.2005.09.025","volume":"46","author":"Long","year":"2006","journal-title":"Protein Expr Purif"},{"key":"10.5051\/jpis.2019.49.2.114_ref4","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0168-1656(01)00425-4","volume":"94","author":"Vallejo","year":"2002","journal-title":"J Biotechnol"},{"key":"10.5051\/jpis.2019.49.2.114_ref5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.5051\/jkape.2008.38.1.41","volume":"38","author":"Choi","year":"2008","journal-title":"J Korean Acad Periodontol"},{"key":"10.5051\/jpis.2019.49.2.114_ref6","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.spinee.2007.06.014","volume":"8","author":"Wong","year":"2008","journal-title":"Spine J"},{"key":"10.5051\/jpis.2019.49.2.114_ref7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S8756-3282(00)00358-6","volume":"27","author":"Kaneko","year":"2000","journal-title":"Bone"},{"key":"10.5051\/jpis.2019.49.2.114_ref8","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1097\/01.brs.0000245863.52371.c2","volume":"31","author":"Smucker","year":"2006","journal-title":"Spine(Phila Pa 1976)"},{"key":"10.5051\/jpis.2019.49.2.114_ref9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.5051\/jpis.2012.42.4.119","volume":"42","author":"Choi","year":"2012","journal-title":"J Periodontal Implant Sci"},{"key":"10.5051\/jpis.2019.49.2.114_ref10","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1093\/jn\/130.10.2409","volume":"130","author":"Yang","year":"2000","journal-title":"J Nutr"},{"key":"10.5051\/jpis.2019.49.2.114_ref11","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1002\/ijc.24677","volume":"125","author":"Tosetti","year":"2009","journal-title":"Int J Cancer"},{"key":"10.5051\/jpis.2019.49.2.114_ref12","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.bcp.2006.07.004","volume":"72","author":"Rahman","year":"2006","journal-title":"Biochem Pharmacol"},{"key":"10.5051\/jpis.2019.49.2.114_ref13","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1006\/bbrc.2002.6622","volume":"292","author":"Nakagawa","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"10.5051\/jpis.2019.49.2.114_ref14","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1600-0765.2004.00743.x","volume":"39","author":"Yun","year":"2004","journal-title":"J Periodontal Res"},{"key":"10.5051\/jpis.2019.49.2.114_ref15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jnutbio.2006.06.005","volume":"18","author":"Vali","year":"2007","journal-title":"J Nutr Biochem"},{"key":"10.5051\/jpis.2019.49.2.114_ref16","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1055\/s-2008-1073164","volume":"40","author":"Tokuda","year":"2008","journal-title":"Horm Metab Res"},{"key":"10.5051\/jpis.2019.49.2.114_ref17","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1002\/jcb.21104","volume":"100","author":"Tokuda","year":"2007","journal-title":"J Cell Biochem"},{"key":"10.5051\/jpis.2019.49.2.114_ref18","first-page":"297","volume":"4","author":"Kato","year":"2011","journal-title":"Mol Med Rep"},{"key":"10.5051\/jpis.2019.49.2.114_ref19","first-page":"265","volume":"26","author":"Kim","year":"2011","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.5051\/jpis.2019.49.2.114_ref20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1023\/A:1022842404495","volume":"14","author":"Daculsi","year":"2003","journal-title":"J Mater Sci Mater Med"},{"key":"10.5051\/jpis.2019.49.2.114_ref21","doi-asserted-by":"crossref","first-page":"166","DOI":"10.5051\/jpis.2012.42.5.166","volume":"42","author":"Choi","year":"2012","journal-title":"J Periodontal Implant Sci"},{"key":"10.5051\/jpis.2019.49.2.114_ref22","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/odi.12109","volume":"20","author":"Shin","year":"2014","journal-title":"Oral Dis"},{"key":"10.5051\/jpis.2019.49.2.114_ref23","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1021\/la980257z","volume":"14","author":"Xiao","year":"1998","journal-title":"Langmuir"},{"key":"10.5051\/jpis.2019.49.2.114_ref24","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1023\/B:JMSM.0000032818.09569.d9","volume":"15","author":"Durrieu","year":"2004","journal-title":"J Mater Sci Mater Med"},{"key":"10.5051\/jpis.2019.49.2.114_ref25","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1600-0501.2011.02222.x","volume":"23","author":"Choi","year":"2012","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2019.49.2.114_ref26","doi-asserted-by":"crossref","DOI":"10.1097\/00008505-199901000-00013","volume-title":"Contemporary implant dentistry","author":"Misch","year":"1999"},{"key":"10.5051\/jpis.2019.49.2.114_ref27","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1600-0765.2006.00935.x","volume":"42","author":"Yun","year":"2007","journal-title":"J Periodontal Res"},{"key":"10.5051\/jpis.2019.49.2.114_ref28","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.bjoms.2005.02.001","volume":"43","author":"Xu","year":"2005","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.5051\/jpis.2019.49.2.114_ref29","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1034\/j.1600-0501.2002.130409.x","volume":"13","author":"Asai","year":"2002","journal-title":"Clin Oral Implants Res"},{"key":"10.5051\/jpis.2019.49.2.114_ref30","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1600-0501.2009.01821.x","volume":"21","author":"Frenken","year":"2010","journal-title":"Clin Oral Implants Res"}],"container-title":["Journal of Periodontal &amp; Implant Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/synapse.koreamed.org\/pdf\/10.5051\/jpis.2019.49.2.114","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T07:15:37Z","timestamp":1589526937000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":30,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.5051\/jpis.2019.49.2.114","relation":{},"ISSN":["2093-2278","2093-2286"],"issn-type":[{"value":"2093-2278","type":"print"},{"value":"2093-2286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","URL":"https:\/\/synapse.koreamed.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","name":"synapse","label":"Synapse","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"https:\/\/www.jpis.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","URL":"https:\/\/www.jpis.org\/DOIx.php?id=10.5051\/jpis.2019.49.2.114","name":"the_journal","label":"the Journal","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2019-02-06","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-19","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2019. Korean Academy of Periodontology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/).","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}