{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T12:05:55Z","timestamp":1769342755900,"version":"3.49.0"},"reference-count":41,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007683","name":"Ministry of Education, Culture, Sports, Science and Technology of Japan and by a Nihon University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007683","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpis.org"],"crossmark-restriction":false},"short-container-title":["J Periodontal Implant Sci"],"DOI":"10.5051\/jpis.2101380069","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:37:26Z","timestamp":1628815046000},"page":"28","update-policy":"https:\/\/doi.org\/10.5051\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Dec2 inhibits macrophage pyroptosis to promote periodontal homeostasis"],"prefix":"10.5051","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2898-8175","authenticated-orcid":false,"given":"Dawei","family":"He","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Mucosa Disease, Dalian Stomatological Hospital, Dalian, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7166-0135","authenticated-orcid":false,"given":"Xiaoyan","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0516-4314","authenticated-orcid":false,"given":"Fengzhu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shenyang Medical College School of Stomatology, Shenyang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1962-1977","authenticated-orcid":false,"given":"Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Histology, Nihon University School of Dentistry at Matsudo, Matsudo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4998-5547","authenticated-orcid":false,"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Laboratory of Tissue Regeneration and Immunology and Department of Periodontics, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Capital Medical University School of Stomatology, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3746-009X","authenticated-orcid":false,"given":"Ujjal K.","family":"Bhawal","sequence":"additional","affiliation":[{"name":"Department of Oral Health, Kanagawa Dental University, Yokosuka, Japan."},{"name":"Department of Biochemistry and Molecular Biology, Nihon University School of Dentistry at Matsudo, Matsudo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3730-3430","authenticated-orcid":false,"given":"Jiang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Mucosa Disease, Dalian Stomatological Hospital, Dalian, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18617","published-online":{"date-parts":[[2022]]},"reference":[{"key":"10.5051\/jpis.2101380069_ref1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11130-019-00736-8","volume":"74","author":"Dia","year":"2019","journal-title":"Plant Foods Hum Nutr"},{"key":"10.5051\/jpis.2101380069_ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jep.2015.02.056","volume":"166","author":"Han","year":"2015","journal-title":"J Ethnopharmacol"},{"key":"10.5051\/jpis.2101380069_ref3","doi-asserted-by":"crossref","first-page":"L733","DOI":"10.1152\/ajplung.00419.2015","volume":"310","author":"D'Alessio","year":"2016","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.5051\/jpis.2101380069_ref4","doi-asserted-by":"crossref","first-page":"L231","DOI":"10.1152\/ajplung.00389.2016","volume":"312","author":"Jiang","year":"2017","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.5051\/jpis.2101380069_ref5","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1038\/ni.2705","volume":"14","author":"Davies","year":"2013","journal-title":"Nat Immunol"},{"key":"10.5051\/jpis.2101380069_ref6","doi-asserted-by":"crossref","first-page":"e1007105","DOI":"10.1371\/journal.ppat.1007105","volume":"14","author":"Wang","year":"2018","journal-title":"PLoS Pathog"},{"key":"10.5051\/jpis.2101380069_ref7","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/978-1-4939-9048-1_20","volume":"1921","author":"Mascarenhas","year":"2019","journal-title":"Methods Mol Biol"},{"key":"10.5051\/jpis.2101380069_ref8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000493585","volume":"11","author":"Riestra","year":"2019","journal-title":"J Innate Immun"},{"key":"10.5051\/jpis.2101380069_ref9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.15698\/mic2018.12.662","volume":"5","author":"O'Meara","year":"2018","journal-title":"Microb Cell"},{"key":"10.5051\/jpis.2101380069_ref10","doi-asserted-by":"crossref","first-page":"e85765","DOI":"10.1371\/journal.pone.0085765","volume":"9","author":"Hu","year":"2014","journal-title":"PLoS One"},{"key":"10.5051\/jpis.2101380069_ref11","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/ni.2231","volume":"13","author":"Franchi","year":"2012","journal-title":"Nat Immunol"},{"key":"10.5051\/jpis.2101380069_ref12","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.mib.2013.04.004","volume":"16","author":"Aachoui","year":"2013","journal-title":"Curr Opin Microbiol"},{"key":"10.5051\/jpis.2101380069_ref13","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1073\/pnas.1211521110","volume":"110","author":"Case","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.5051\/jpis.2101380069_ref14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nrmicro2070","volume":"7","author":"Bergsbaken","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.5051\/jpis.2101380069_ref15","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/nrmicro2873","volume":"10","author":"Hajishengallis","year":"2012","journal-title":"Nat Rev Microbiol"},{"key":"10.5051\/jpis.2101380069_ref16","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.yexcr.2017.03.028","volume":"354","author":"Yoshida","year":"2017","journal-title":"Exp Cell Res"},{"key":"10.5051\/jpis.2101380069_ref17","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1038\/cr.2015.139","volume":"25","author":"He","year":"2015","journal-title":"Cell Res"},{"key":"10.5051\/jpis.2101380069_ref18","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature10558","volume":"479","author":"Kayagaki","year":"2011","journal-title":"Nature"},{"key":"10.5051\/jpis.2101380069_ref19","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1902\/jop.2014.140403","volume":"86","author":"Huang","year":"2015","journal-title":"J Periodontol"},{"key":"10.5051\/jpis.2101380069_ref20","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1128\/IAI.00862-13","volume":"82","author":"Park","year":"2014","journal-title":"Infect Immun"},{"key":"10.5051\/jpis.2101380069_ref21","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1111\/j.1462-5822.2008.01185.x","volume":"10","author":"Wang","year":"2008","journal-title":"Cell Microbiol"},{"key":"10.5051\/jpis.2101380069_ref22","doi-asserted-by":"crossref","first-page":"e1004215","DOI":"10.1371\/journal.ppat.1004215","volume":"10","author":"Slocum","year":"2014","journal-title":"PLoS Pathog"},{"key":"10.5051\/jpis.2101380069_ref23","doi-asserted-by":"crossref","first-page":"6320","DOI":"10.4049\/jimmunol.0900975","volume":"183","author":"Liu","year":"2009","journal-title":"J Immunol"},{"key":"10.5051\/jpis.2101380069_ref24","doi-asserted-by":"crossref","first-page":"e00361","DOI":"10.1128\/IAI.00361-18","volume":"86","author":"Lacey","year":"2018","journal-title":"Infect Immun"},{"key":"10.5051\/jpis.2101380069_ref25","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/jre.12849","volume":"56","author":"Oka","year":"2021","journal-title":"J Periodontal Res"},{"key":"10.5051\/jpis.2101380069_ref26","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12903-016-0250-8","volume":"17","author":"Sun","year":"2016","journal-title":"BMC Oral Health"},{"key":"10.5051\/jpis.2101380069_ref27","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/jre.12578","volume":"53","author":"Zhang","year":"2018","journal-title":"J Periodontal Res"},{"key":"10.5051\/jpis.2101380069_ref28","doi-asserted-by":"crossref","first-page":"45126","DOI":"10.1038\/srep45126","volume":"7","author":"Man","year":"2017","journal-title":"Sci Rep"},{"key":"10.5051\/jpis.2101380069_ref29","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/j.celrep.2014.02.015","volume":"6","author":"Py","year":"2014","journal-title":"Cell Reports"},{"key":"10.5051\/jpis.2101380069_ref30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.imbio.2017.11.001","volume":"223","author":"Arora","year":"2018","journal-title":"Immunobiology"},{"key":"10.5051\/jpis.2101380069_ref31","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/mi.2015.44","volume":"9","author":"Schaale","year":"2016","journal-title":"Mucosal Immunol"},{"key":"10.5051\/jpis.2101380069_ref32","doi-asserted-by":"crossref","first-page":"10642","DOI":"10.1073\/pnas.1708194114","volume":"114","author":"Kuang","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.5051\/jpis.2101380069_ref33","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/s41419-019-2021-3","volume":"10","author":"Jia","year":"2019","journal-title":"Cell Death Dis"},{"key":"10.5051\/jpis.2101380069_ref34","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nature15514","volume":"526","author":"Shi","year":"2015","journal-title":"Nature"},{"key":"10.5051\/jpis.2101380069_ref35","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/nature15541","volume":"526","author":"Kayagaki","year":"2015","journal-title":"Nature"},{"key":"10.5051\/jpis.2101380069_ref36","doi-asserted-by":"crossref","first-page":"e3000047","DOI":"10.1371\/journal.pbio.3000047","volume":"16","author":"Xiao","year":"2018","journal-title":"PLoS Biol"},{"key":"10.5051\/jpis.2101380069_ref37","doi-asserted-by":"crossref","first-page":"e12414","DOI":"10.1111\/jpi.12414","volume":"63","author":"Liu","year":"2017","journal-title":"J Pineal Res"},{"key":"10.5051\/jpis.2101380069_ref38","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fmicb.2011.00015","volume":"2","author":"Skeldon","year":"2011","journal-title":"Front Microbiol"},{"key":"10.5051\/jpis.2101380069_ref39","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1007\/s10753-018-0858-8","volume":"41","author":"Yuan","year":"2018","journal-title":"Inflammation"},{"key":"10.5051\/jpis.2101380069_ref40","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/nri2873","volume":"10","author":"Chen","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"10.5051\/jpis.2101380069_ref41","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/jre.12849","volume":"56","author":"Oka","year":"2021","journal-title":"J Periodontal Res"}],"container-title":["Journal of Periodontal & Implant Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jpis.org\/pdf\/10.5051\/jpis.2101380069","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2101380069","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2101380069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T01:58:37Z","timestamp":1645063117000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpis.org\/DOIx.php?id=10.5051\/jpis.2101380069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.5051\/jpis.2101380069","relation":{},"ISSN":["2093-2278","2093-2286"],"issn-type":[{"value":"2093-2278","type":"print"},{"value":"2093-2286","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"2021-02-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-21","name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-12","name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"Copyright \u00a9 2022. Korean Academy of Periodontology","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/).","name":"license","label":"License","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}