{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T02:32:07Z","timestamp":1778207527334,"version":"3.51.4"},"reference-count":28,"publisher":"Weston Medical Publishing","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Opioid Management"],"abstract":"<jats:p>Objective: This study assessed the impact of erector spinae plane block (ESPB) and intravenous (IV) dexmedetomidine in reduction of perioperative opioid consumption following bariatric surgery and their impact on post-operative recovery, analgesia, and pulmonary functions.\r\nDesign: A randomized controlled trial.\r\nSetting: Tanta University Hospitals, Tanta, Gharboa, Egypt.\r\nPatients: Forty obese patients with obstructive sleep apnea syndrome (OSAS), aged 20-55 years, and eligible for bariatric surgery were included.\r\nInterventions: Patients randomized into group I (received general anesthesia [GA] with opioid, sham ESPB, and IV normal saline) or group II (received GA [without opioid], ESPB [at T7 level] using 20 mL bupivacaine 0.25 percent and bolus IV dexmedetomidine 1 \u03bcg\/kg and then 0.25 \u03bcg\/kg\/h).\r\nMain outcome measures: Fentanyl consumption (primary outcome), sevoflurane consumption, recovery time, Visual Analog Scale (VAS), and pulmonary functions (secondary outcomes) were recorded.\r\nResults: Perioperative fentanyl (intraoperative, post-operative, and total) consumption and sevoflurane consumption were substantially lower in group II compared to group I (p = 0.010, &lt;0.001, &lt;0.001, and &lt;0.001, respectively). Moreover, recovery time was shorter in group II (p &lt; 0.001). At 2, 4, 8, and 24 hours after surgery, group I patients had VAS values considerably higher. Relative to preoperative values, pulmonary function did not significantly alter after surgery. Oxygen desaturation was significantly lower in group II (p = 0.001).\r\nConclusions: The ESPB with IV dexmedetomidine is advantageous for OSAS patients having bariatric surgery as it provides anesthesia and opioid-sparing effect with short recovery, adequate analgesia, and nonsignificant complications. Yet, it had no effect on post-operative pulmonary function.<\/jats:p>","DOI":"10.5055\/jom.0873","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T23:22:19Z","timestamp":1720826539000},"page":"243-253","source":"Crossref","is-referenced-by-count":2,"title":["Opioid-sparing effect of erector spinae plane block and intravenous dexmedetomidine for obese patients with obstructive sleep apnea: A randomized controlled trial"],"prefix":"10.5055","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7087-864X","authenticated-orcid":false,"given":"Mona Raafat","family":"Elghamry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2866-1295","authenticated-orcid":false,"given":"Atteia Gad","family":"Anwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7835-3653","authenticated-orcid":false,"given":"Shaimaa Waheed","family":"Zahra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3008","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"91005","doi-asserted-by":"crossref","unstructured":"Lam KM: Multimodal analgesia model to achieve low postoperative opioid requirement following bariatric surgery. 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J Clin Anesth. 2018; 49: 101-106.","DOI":"10.1016\/j.jclinane.2018.06.019"},{"key":"91016","doi-asserted-by":"crossref","unstructured":"Alt\u0131parmak B, Toker MK, Uysal AI, et al.: Ultrasound-guided erector spinae plane block versus oblique subcostal transversus abdominis plane block for postoperative analgesia of adult patients undergoing laparoscopic cholecystectomy: Randomized, controlled trial. J Clin Anesth. 2019; 57: 31-36.","DOI":"10.1016\/j.jclinane.2019.03.012"},{"key":"91017","doi-asserted-by":"crossref","unstructured":"Elyazed MM, Mostafa SF, Abdelghany MS, et al.: Ultrasound-guided erector spinae plane block in patients undergoing open epigastric hernia repair: A prospective randomized controlled study. 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