{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T12:42:22Z","timestamp":1747226542292,"version":"3.40.5"},"reference-count":0,"publisher":"Weston Medical Publishing","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Opioid Management"],"abstract":"<jats:p>Objective: To assess the impact of extended-release (ER)\/long-acting (LA) opioid prescriber training on prescribing behaviors.Design: Retrospective cohort study.Setting: Prescriber training was evaluated from June 1, 2013 through December 31, 2016. The full study period was 2 years longer, from June 1, 2012 through December 31, 2017, to include data for all prescribers\u2019 1-year pretraining and post-training periods.Participants: 24,428 prescribers who wrote ER\/LA opioid prescriptions for eligible patients, with a record of training from the partner continuing education provider between June 1, 2013 and December 31, 2016.Intervention: ER\/LA opioid prescriber training. Main outcome measures: Prescribing behaviors 1-year before (pretraining) and after (post-training) prescribers completed training, specifically the proportion of opioid-nontolerant patients receiving ER\/LA opioids indicated for opioid-tolerant patients and for patients receiving \u2265100 morphine equivalents dose daily, and the proportion of concomitant users of central nervous system depressant drugs.Results: The differences in the proportion of opioid-nontolerant patients receiving ER\/LA opioids indicated for opioid-tolerant patients and for patients receiving \u2265100 morphine equivalents dose daily were \u20130.69 percent (95 percent confidence interval [CI]: \u20131.78 percent, 0.40 percent) and \u20130.23 percent (95 percent CI: \u20131.18 percent, 0.68 percent), respectively. The differences in the proportion of concomitant users of central nervous system depressant drugs were \u20130.94 percent (95 percent CI: \u20131.39 percent; \u20130.48 percent) for benzodiazepines, 0.06 percent (95 percent CI: \u20130.13 percent; 0.25 percent) for antipsychotics, \u20130.41 percent (95 percent CI: \u20130.69 percent; \u20130.13 percent) for hypnotics\/sedatives, and 0.08 percent (95 percent CI: \u20130.40 percent; 0.57 percent) for muscle relaxants.Conclusions: While prescribers showed some changes in prescribing behavior after completing training, training was not associated with clinically relevant changes in prescribing behaviors.<\/jats:p>","DOI":"10.5055\/jom.2023.0764","type":"journal-article","created":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T00:37:09Z","timestamp":1678495029000},"page":"99-110","source":"Crossref","is-referenced-by-count":0,"title":["Impact of the extended-release\/long-acting opioid analgesics risk evaluation and mitigation strategy on prescribing practices"],"prefix":"10.5055","volume":"19","author":[{"given":"Matthew H.","family":"Secrest, MSc","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9054-8587","authenticated-orcid":false,"given":"Syd","family":"Phillips, MPH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Soledad","family":"Cepeda, MD, PhD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Kern, MS, PhD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daina B.","family":"Esposito, MPH, PhD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory P.","family":"Wedin, PharmD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3008","published-online":{"date-parts":[[2023,3,1]]},"container-title":["Journal of Opioid Management"],"original-title":[],"link":[{"URL":"https:\/\/wmpllc.org\/ojs\/index.php\/jom\/article\/download\/3359\/3650","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/wmpllc.org\/ojs\/index.php\/jom\/article\/download\/3359\/3650","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T18:54:20Z","timestamp":1682967260000},"score":1,"resource":{"primary":{"URL":"https:\/\/wmpllc.org\/ojs\/index.php\/jom\/article\/view\/3359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.5055\/jom.2023.0764","relation":{},"ISSN":["1551-7489","1551-7489"],"issn-type":[{"type":"electronic","value":"1551-7489"},{"type":"print","value":"1551-7489"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}