{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:25:59Z","timestamp":1767374759106,"version":"3.40.3"},"reference-count":13,"publisher":"Termedia Sp. z.o.o.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesiol Intensive Ther"],"abstract":"Introduction<\/jats:title>Epidural volume extension is technique aiming to mitigate spinal anaesthesia induced hypotension, by reducing the dose of local anaesthetics. The present study was executed to determine the effect of epidural volume extension subarachnoid block with 0.5% hyperbaric bupivacaine in patients undergoing proximal femoral nailing (PFN) regarding characteristics of sensory-motor block and postoperative analgesia.<\/jats:p><\/jats:sec>Material and methods<\/jats:title>In this prospective, double-blind trial conducted from October 2021 to April 2022, 105 adult patients scheduled to undergo PFN were randomised into groups: control (C), 10 mL NS (E1), and 20 mL NS (E2), to receive 10 mg hyperbaric bupivacaine intrathecally plus additional epidural volume extension with 10 and 20 mL normal saline in groups E1 and E2, respectively. The primary outcome measured was the duration of postoperative analgesia. The secondary outcomes measured included onset of sensory- motor block and duration of sensory block. <i>P<\/i> < 0.05 was considered statistically significant.<\/jats:p><\/jats:sec>Results<\/jats:title>A significantly longer duration of postoperative analgesia was noted in patients receiving 10 and 20 mL epidural volume extension (365.09 \u00b1 101.83 and 330.06 \u00b1 35.22 vs. 265.77 \u00b1 38.01 min in the control group, <i>P<\/i> < 0.01). Patients who received any epidural volume extension with either 10 or 20 mL had significantly quicker onset of sensory and motor block as well as prolonged duration of sensory block. No significant difference in duration of postoperative analgesia, and onset and duration of block was observed between patients receiving either 10 or 20 mL epidural volume extension.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Epidural volume extension significantly shortened the onset of sensory-motor block and increased the duration of sensory block and postoperative analgesia in patients undergoing PFN under subarachnoid block; however, no such difference was observed between 10 and 20 mL epidural volume extension.<\/jats:p><\/jats:sec>","DOI":"10.5114\/ait.2023.134246","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T07:54:42Z","timestamp":1706514882000},"page":"366-371","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of impact of epidural volume extension on the quality of spinal anaesthesia in patients undergoing proximal femoral nailing surgeries \u2013 randomized controlled study"],"prefix":"10.5114","volume":"55","author":[{"given":"Vikram","family":"Bedi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanghamitra","family":"Debbarma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Navaria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anchal","family":"Jhawer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santosh","family":"Choudhary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3061","published-online":{"date-parts":[[2023,12,30]]},"reference":[{"key":"ref-1374142","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-021-00556-0"},{"key":"ref-1374143","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.91980"},{"key":"ref-1374144","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_1082_21"},{"key":"ref-1374145","doi-asserted-by":"publisher","DOI":"10.4103\/0259-1162.108350"},{"key":"ref-1374146","doi-asserted-by":"publisher","DOI":"10.4103\/ija.IJA_703_18"},{"key":"ref-1374147","doi-asserted-by":"crossref","first-page":"224","DOI":"10.18231\/j.ijca.2019.042","article-title":"A prospective randomised comparative study between 10 ml and 15 ml of normal saline for epidural volume expansion on 10 mg of 0.5% hyperbaric bupivacaine spinal anesthesia for elective infraumbilical surgeries in adult patients","volume":"6","author":"Singh S","year":"2019","unstructured":"Singh S, Vijayalakshmi BC, Kattishettar D. A prospective randomised comparative study between 10 ml and 15 ml of normal saline for epidural volume expansion on 10 mg of 0.5% hyperbaric bupivacaine spinal anesthesia for elective infraumbilical surgeries in adult patients. Indian J Clin Anaesth 2019; 6: 224-228.","journal-title":"Indian J Clin Anaesth"},{"key":"ref-1374148","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181734436"},{"key":"ref-1374149","first-page":"14","article-title":"Comparative study between sequential combined spinal epidural anaesthesia versus epidural volume extension in lower limb surgery","volume":"12","author":"Hakim KYK","year":"2020","unstructured":"Hakim KYK. Comparative study between sequential combined spinal epidural anaesthesia versus epidural volume extension in lower limb surgery. Ain-Shams J Anesthesiol 2020; 12: 14.","journal-title":"Ain-Shams J Anesthesiol"},{"key":"ref-1374150","doi-asserted-by":"publisher","DOI":"10.4103\/aer.AER_189_17"},{"key":"ref-1374151","doi-asserted-by":"crossref","first-page":"350","DOI":"10.4103\/1687-7934.139565","article-title":"Epidural volume extension with saline in combined spinal epidural anaesthesia for dynamic hip screw surgeries using low dose of intrathecal hyperbaric bupivacaine","volume":"7","author":"Okasha M","year":"2014","unstructured":"Okasha M, Kamal S, Ramzy A. Epidural volume extension with saline in combined spinal epidural anaesthesia for dynamic hip screw surgeries using low dose of intrathecal hyperbaric bupivacaine. Ain-Shams Journal of Anesthesiology 2014; 7: 350-355.","journal-title":"Ain-Shams Journal of Anesthesiology"},{"key":"ref-1374152","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1905-44"},{"key":"ref-1374153","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000850"},{"key":"ref-1374154","first-page":"279","article-title":"Effect of epidural volume extension and combined spinal-anaesthesia of parturient in women undergoing cesarean delivery","volume":"47","author":"Xiong Y","year":"2016","unstructured":"Xiong Y, Liao Z, Cai Y, Zhu Q, Tang Y. Effect of epidural volume extension and combined spinal-anaesthesia of parturient in women undergoing cesarean delivery. Sichuan Da Xue Xue Bao Yi Xue Ban 2016; 47: 279-282 [Article in Chinese].","journal-title":"Sichuan Da Xue Xue Bao Yi Xue Ban"}],"container-title":["Anaesthesiology Intensive Therapy"],"original-title":[],"link":[{"URL":"https:\/\/www.ait-journal.com\/pdf-172853-121695","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ait-journal.com\/pdf-172853-121695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T10:23:18Z","timestamp":1743070998000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ait-journal.com\/Evaluation-of-impact-of-epidural-volume-extension-on-the-quality-of-spinal-anaesthesia,172853,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,30]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023]]}},"alternative-id":["172853"],"URL":"https:\/\/doi.org\/10.5114\/ait.2023.134246","relation":{},"ISSN":["1642-5758","1731-2531"],"issn-type":[{"type":"print","value":"1642-5758"},{"type":"electronic","value":"1731-2531"}],"subject":[],"published":{"date-parts":[[2023,12,30]]}}}